Publications

Letter to the Editor: Molecularly defined oligodendroglioma evolving to osseous metastases.
Journal of neuropathology and experimental neurology. 2025 Apr 18; Authors: Pai EL, Matsumoto Y, Dou D, Nelluri S, Devi P, Priori S, Amankulor N, Alonso-Basanta M, Singh O, Abdullaev Z, Aldape K, Desai A, Mohan S, Nasrallah MP

Corticosteroid-Dependent Association between Prognostic Peripheral Blood Cell-Free DNA Levels and Neutrophil-Mediated NETosis in Patients with Glioblastoma.
Clinical cancer research : an official journal of the American Association for Cancer Research. 2025 Apr 1;31(7):1292-1304; Authors: Till JE, Seewald NJ, Yazdani Z, Wang Z, Ballinger D, Samberg H, Dandu S, Macia C, Yin M, Abdalla A, Prior T, Shah SS, Patel T, McCoy E, Mansour M, Wills CA, Bochenek V, Serrano J, Snuderl M, Phillips RE, O'Rourke DM, Amankulor NM, Nabavizadeh A, Desai AS, Gollomp K, Binder ZA, Zhou W, Bagley SJ, Carpenter EL

A multi-institutional phase 1 clinical trial exploring upfront multimodal standard of care and combined immunotherapies for newly diagnosed glioblastoma.
Neuro-oncology. 2025 Mar 22; Authors: Wen PY, Manzanera A, Duault C, Gonzalez-Kozlova E, Lopez L, Grossman SA, Ye X, Fisher J, Lee I, Walbert T, Snyder J, Brem S, Desai A, Bagley SJ, Kakani C, Strowd R, Tatter S, Laxton A, Lesser G, Amankulor N, Lieberman F, Drappatz J, Mantica M, Triggs D, Haymaker C, Wistuba II, Al-Atrash G, Mendoza Perez J, Futreal A, Little LD, Islam MDH, Duose D, Jiang P, Reuben A, Lawler SE, Pichavant M, Gentles A, Bendall S, Kong A, Camacho C, Del Valle D, Kim-Schulze S, Gnjatic S, Sharon E, Nowicki MO, Peruzzi P, Lane D, Aguilar-Cordova E, Aguilar LK, Nichols G, Dwyer J, Tak PP, Maecker H, Barone F, Chiocca EA

Machine Learning-based Prognostic Subgrouping of Glioblastoma: A Multi-center Study.
Neuro-oncology. 2024 Dec 12; Authors: Akbari H, Bakas S, Sako C, Fathi Kazerooni A, Villanueva-Meyer J, Garcia JA, Mamourian E, Liu F, Cao Q, Shinohara RT, Baid U, Getka A, Pati S, Singh A, Calabrese E, Chang S, Rudie J, Sotiras A, LaMontagne P, Marcus DS, Milchenko M, Nazeri A, Balana C, Capellades J, Puig J, Badve C, Barnholtz-Sloan JS, Sloan AE, Vadmal V, Waite K, Ak M, Colen RR, Park YW, Ahn SS, Chang JH, Choi YS, Lee SK, Alexander GS, Ali AS, Dicker AP, Flanders AE, Liem S, Lombardo J, Shi W, Shukla G, Griffith B, Poisson LM, Rogers LR, Kotrotsou A, Booth TC, Jain R, Lee M, Mahajan A, Chakravarti A, Palmer JD, DiCostanzo D, Fathallah-Shaykh H, Cepeda S, Santonocito OS, Di Stefano AL, Wiestler B, Melhem ER, Woodworth GF, Tiwari P, Valdes P, Matsumoto Y, Otani Y, Imoto R, Aboian M, Koizumi S, Kurozumi K, Kawakatsu T, Alexander K, Satgunaseelan L, Rulseh AM, Bagley SJ, Bilello M, Binder ZA, Brem S, Desai AS, Lustig RA, Maloney E, Prior T, Amankulor N, Nasrallah MLP, O'Rourke DM, Mohan S, Davatzikos C, ReSPOND consortium

Cerebrospinal Fluid Seeding Versus Inflammation in Setting of Ventriculoperitoneal Shunt as a Potential Cause for Distant Recurrence of Glioblastoma.
Brain tumor research and treatment. 2024 Jul;12(3):181-185; Authors: Gersey ZC, Plute T, Jaman E, Zhang X, Mitha R, Zinn PO, Pearce TM, Amankulor NM

Preoperative stereotactic radiosurgery for cerebral metastases: safe, effective, and decreases steroid dependency.
Journal of neurosurgery. 2024 Nov 1;141(5):1332-1342 Epub 2024 May 10; Authors: Mallela AN, Iheagwara UK, Fogg D, Anthony A, Gersey ZC, Zhang X, Abou-Al-Shaar H, Anand SK, Xu E, Zinn PO, Burton S, Quinn A, Ozhasoglu C, Clump DA, Siddiqui Z, Amankulor NM

BRAF V600E in a preclinical model of pleomorphic Xanthoastrocytoma: Analysis of the tumor microenvironment and immune cell infiltration dynamics in vivo.
Molecular therapy. Oncology. 2024 Jun 20;32(2):200808 Epub 2024 Apr 25; Authors: Canella A, Nazzaro M, Artomov M, Rao Venkata LP, Thomas D, Lyberger J, Ukhatov A, Xing YL, Miller K, Behbehani G, Amankulor NM, Petritsch CK, Rajappa P

All-trans retinoic acid induces durable tumor immunity in IDH-mutant gliomas by rescuing transcriptional repression of the CRBP1-retinoic acid axis.
bioRxiv : the preprint server for biology. 2024 Apr 13; Authors: Rao A, Zhang X, Cillo AR, Sussman JH, Sandlesh P, Tarbay AC, Mallela AN, Cardello C, Krueger K, Xu J, Li A, Xu J, Patterson J, Akca E, Angione A, Jaman E, Kim WJ, Allen J, Venketeswaran A, Zinn PO, Parise R, Beumer J, Duensing A, Holland EC, Ferris R, Bagley SJ, Bruno TC, Vignali DAA, Agnihotri S, Amankulor NM

A longitudinal single-cell and spatial multiomic atlas of pediatric high-grade glioma.
bioRxiv : the preprint server for biology. 2024 Mar 8; Authors: Sussman JH, Oldridge DA, Yu W, Chen CH, Zellmer AM, Rong J, Parvaresh-Rizi A, Thadi A, Xu J, Bandyopadhyay S, Sun Y, Wu D, Emerson Hunter C, Brosius S, Ahn KJ, Baxter AE, Koptyra MP, Vanguri RS, McGrory S, Resnick AC, Storm PB, Amankulor NM, Santi M, Viaene AN, Zhang N, Raedt T, Cole K, Tan K

An ERK5-PFKFB3 axis regulates glycolysis and represents a therapeutic vulnerability in pediatric diffuse midline glioma.
Cell reports. 2024 Jan 23;43(1):113557 Epub 2023 Dec 18; Authors: Casillo SM, Gatesman TA, Chilukuri A, Varadharajan S, Johnson BJ, David Premkumar DR, Jane EP, Plute TJ, Koncar RF, Stanton AJ, Biagi-Junior CAO, Barber CS, Halbert ME, Golbourn BJ, Halligan K, Cruz AF, Mansi NM, Cheney A, Mullett SJ, Land CV, Perez JL, Myers MI, Agrawal N, Michel JJ, Chang YF, Vaske OM, MichaelRaj A, Lieberman FS, Felker J, Shiva S, Bertrand KC, Amankulor N, Hadjipanayis CG, Abdullah KG, Zinn PO, Friedlander RM, Abel TJ, Nazarian J, Venneti S, Filbin MG, Gelhaus SL, Mack SC, Pollack IF, Agnihotri S

A novel ARIH1::BRAF fusion in a glioma.
Journal of neuropathology and experimental neurology. 2023 Oct 20;82(11):966-969; Authors: Xu E, Stone SL, Zhong Y, Golenberg N, Qiu L, Abdullaev Z, Aldape K, Bagley L, Halpern CH, Amankulor N, Nasrallah MP

TP53-PTEN-NF1 depletion in human brain organoids produces a glioma phenotype in vitro.
Frontiers in oncology. 2023;13:1279806 Epub 2023 Oct 10; Authors: Singh SK, Wang Y, Habib A, Priyadarshini M, Kodavali CV, Chen A, Ma W, Wang J, Hameed NUF, Hu B, Fuller GN, Kulich SM, Amankulor N, Colen RR, Edwards LA, Zinn PO

Super-enhancer hijacking drives ectopic expression of hedgehog pathway ligands in meningiomas.
Nature communications. 2023 Oct 7;14(1):6279; Authors: Youngblood MW, Erson-Omay Z, Li C, Najem H, Coșkun S, Tyrtova E, Montejo JD, Miyagishima DF, Barak T, Nishimura S, Harmancı AS, Clark VE, Duran D, Huttner A, Avşar T, Bayri Y, Schramm J, Boetto J, Peyre M, Riche M, Goldbrunner R, Amankulor N, Louvi A, Bilgüvar K, Pamir MN, Özduman K, Kilic T, Knight JR, Simon M, Horbinski C, Kalamarides M, Timmer M, Heimberger AB, Mishra-Gorur K, Moliterno J, Yasuno K, Günel M

Outcomes and Treatment Algorithm in Glioblastoma Patients 80 Years and Older.
World neurosurgery. 2023 Oct;178:e540-e548 Epub 2023 Jul 28; Authors: Fogg D, Gersey ZC, Pease M, Mallela AN, Andrews E, Plute T, Pearce TM, Njoku-Austin C, Anthony A, Amankulor NM, Zinn P

Genetically modified IL2 bone-marrow-derived myeloid cells reprogram the glioma immunosuppressive tumor microenvironment.
Cell reports. 2023 Aug 29;42(8):112891 Epub 2023 Jul 28; Authors: Canella A, Nazzaro M, Rajendran S, Schmitt C, Haffey A, Nigita G, Thomas D, Lyberger JM, Behbehani GK, Amankulor NM, Mardis ER, Cripe TP, Rajappa P

Dissecting the tumor microenvironment of epigenetically driven gliomas: Opportunities for single-cell and spatial multiomics.
Neuro-oncology advances. 2023 Jan-Dec;5(1):vdad101 Epub 2023 Aug 21; Authors: Sussman JH, Xu J, Amankulor N, Tan K

Headlight and loupe-based fluorescein detection system in brain tumor surgery: a first-in-human experience.
Journal of neurosurgical sciences. 2023 Jun;67(3):374-379 Epub 2021 Oct 14; Authors: Zhang X, Habib A, Jaman E, Mallela AN, Amankulor NM, Zinn PO

Distinguishing Progression from Pseudoprogression in Glioblastoma Using (18)F-Fluciclovine PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2023 Jun;64(6):852-858 Epub 2022 Dec 22; Authors: Nabavizadeh A, Bagley SJ, Doot RK, Ware JB, Young AJ, Ghodasara S, Zhao C, Anderson H, Schubert E, Carpenter EL, Till J, Henderson F Jr, Pantel AR, Chen HI, Lee JYK, Amankulor NM, O'Rourke DM, Desai A, Nasrallah MP, Brem S

PHGDH-mediated endothelial metabolism drives glioblastoma resistance to chimeric antigen receptor T cell immunotherapy.
Cell metabolism. 2023 Mar 7;35(3):517-534.e8 Epub 2023 Feb 17; Authors: Zhang D, Li AM, Hu G, Huang M, Yang F, Zhang L, Wellen KE, Xu X, Conn CS, Zou W, Kahn M, Rhoades SD, Weljie AM, Fuchs SY, Amankulor N, Yoshor D, Ye J, Koumenis C, Gong Y, Fan Y

Clinical Features Associated with Outcomes and Biomarker Analysis of Dabrafenib plus Trametinib Treatment in Patients with BRAF-Mutant Melanoma Brain Metastases.
Clinical cancer research : an official journal of the American Association for Cancer Research. 2023 Feb 1;29(3):521-531; Authors: Wilmott JS, Tawbi H, Engh JA, Amankulor NM, Shivalingam B, Banerjee H, Vergara IA, Lee H, Johansson PA, Ferguson PM, Saiag P, Robert C, Grob JJ, Butterfield LH, Scolyer RA, Kirkwood JM, Long GV, Davies MA

Risk of intracranial hemorrhage with direct oral anticoagulants vs low molecular weight heparin in glioblastoma: A retrospective cohort study.
Neuro-oncology. 2022 Dec 1;24(12):2172-2179; Authors: Reed-Guy L, Desai AS, Phillips RE, Croteau D, Albright K, O'Neill M, Brem S, O'Rourke DM, Amankulor NM, Bagley SJ

Matched analysis of patient gender and meningioma resection outcomes.
British journal of neurosurgery. 2022 Oct;36(5):613-619 Epub 2022 Apr 21; Authors: Howard SD, Kvint S, Borja AJ, Dimentberg R, Shultz K, Amankulor NM, McClintock SD, Malhotra NR

Machine Learning Identification of Immunotherapy Targets in Low-Grade Glioma Using RNA Sequencing Expression Data.
World neurosurgery. 2022 Jul;163:e349-e362 Epub 2022 Apr 4; Authors: Agarwal P, Beale OM, Zhang X, Sandlesh P, Jaman E, Amankulor N

Author Correction: Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome.
Nature cancer. 2022 Jul;3(7):899; Authors: Golbourn BJ, Halbert ME, Halligan K, Varadharajan S, Krug B, Mbah NE, Kabir N, Stanton AJ, Locke AL, Casillo SM, Zhao Y, Sanders LM, Cheney A, Mullett SJ, Chen A, Wassell M, Andren A, Perez J, Jane EP, Premkumar DRD, Koncar RF, Mirhadi S, McCarl LH, Chang YF, Wu YL, Gatesman TA, Cruz AF, Zapotocky M, Hu B, Kohanbash G, Wang X, Vartanian A, Moran MF, Lieberman F, Amankulor NM, Wendell SG, Vaske OM, Panigrahy A, Felker J, Bertrand KC, Kleinman CL, Rich JN, Friedlander RM, Broniscer A, Lyssiotis C, Jabado N, Pollack IF, Mack SC, Agnihotri S

Targeting the translational machinery in gastrointestinal stromal tumors (GIST): a new therapeutic vulnerability.
Scientific reports. 2022 May 18;12(1):8275; Authors: Lee DM, Sun A, Patil SS, Liu L, Rao AV, Trent PT, Ali AA, Liu C, Rausch JL, Presutti LD, Kaczorowski A, Schneider F, Amankulor NM, Shuda M, Duensing A

A Novel 5-Aminolevulinic Acid-Enabled Surgical Loupe System-A Consecutive Brain Tumor Series of 11 Cases.
Operative neurosurgery (Hagerstown, Md.). 2022 May 1;22(5):298-304; Authors: Zhang X, Jaman E, Habib A, Ozpinar A, Andrews E, Amankulor NM, Zinn PO

Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome.
Nature cancer. 2022 May;3(5):629-648 Epub 2022 Apr 14; Authors: Golbourn BJ, Halbert ME, Halligan K, Varadharajan S, Krug B, Mbah NE, Kabir N, Stanton AJ, Locke AL, Casillo SM, Zhao Y, Sanders LM, Cheney A, Mullett SJ, Chen A, Wassell M, Andren A, Perez J, Jane EP, Premkumar DRD, Koncar RF, Mirhadi S, McCarl LH, Chang YF, Wu YL, Gatesman TA, Cruz AF, Zapotocky M, Hu B, Kohanbash G, Wang X, Vartanian A, Moran MF, Lieberman F, Amankulor NM, Wendell SG, Vaske OM, Panigrahy A, Felker J, Bertrand KC, Kleinman CL, Rich JN, Friedlander RM, Broniscer A, Lyssiotis C, Jabado N, Pollack IF, Mack SC, Agnihotri S

The Subventricular Zone in Glioblastoma: Genesis, Maintenance, and Modeling.
Frontiers in oncology. 2022;12:790976 Epub 2022 Mar 10; Authors: Beiriger J, Habib A, Jovanovich N, Kodavali CV, Edwards L, Amankulor N, Zinn PO

A liquid fraction of extracellular matrix inhibits glioma cell viability in vitro and in vivo.
Oncotarget. 2022;13:426-438 Epub 2022 Feb 21; Authors: Murdock MH, Hussey GS, Chang JT, Hill RC, Nascari DG, Rao AV, Hansen KC, Foley LM, Hitchens TK, Amankulor NM, Badylak SF

Percutaneous fixation for the treatment of metastatic spinal disease provides effective symptom palliation with low rates of hardware failure.
Surgical neurology international. 2022;13:50 Epub 2022 Feb 11; Authors: Jaman E, Zhang X, Allen J, Saraiya RG, Tollefson S, Hamilton DK, Amankulor NM

Characterization of systemic immunosuppression by IDH mutant glioma small extracellular vesicles.
Neuro-oncology. 2022 Feb 1;24(2):197-209; Authors: Ludwig N, Rao A, Sandlesh P, Yerneni SS, Swain AD, Bullock KM, Hansen KM, Zhang X, Jaman E, Allen J, Krueger K, Hong CS, Banks WA, Whiteside TL, Amankulor NM

In vivo efficacy of decitabine as a natural killer cell-mediated immunotherapy against isocitrate dehydrogenase mutant gliomas.
Neurosurgical focus. 2022 Feb;52(2):E3; Authors: Zhang X, Kim WJ, Rao AV, Jaman E, Deibert CP, Sandlesh P, Krueger K, Allen JC, Amankulor NM

The dominant TP53 hotspot mutation in IDH -mutant astrocytoma, R273C, has distinctive pathologic features and sex-specific prognostic implications.
Neuro-oncology advances. 2022 Jan-Dec;4(1):vdab182 Epub 2021 Dec 11; Authors: Marker DF, Agnihotri S, Amankulor N, Murdoch GH, Pearce TM

The Evolving Role of Induced Pluripotent Stem Cells and Cerebral Organoids in Treating and Modeling Neurosurgical Diseases.
World neurosurgery. 2021 Nov;155:171-179 Epub 2021 Aug 25; Authors: Jovanovich N, Habib A, Kodavali C, Edwards L, Amankulor N, Zinn PO

History of atopy confers improved outcomes in IDH mutant and wildtype lower grade gliomas.
Journal of neuro-oncology. 2021 Nov;155(2):133-141 Epub 2021 Oct 29; Authors: Jaman E, Zhang X, Sandlesh P, Habib A, Allen J, Saraiya RG, Amankulor NM, Zinn PO

Autophagy inhibition is the next step in the treatment of glioblastoma patients following the Stupp era.
Cancer gene therapy. 2021 Sep;28(9):971-983 Epub 2020 Aug 5; Authors: Zhang X, Deibert CP, Kim WJ, Jaman E, Rao AV, Lotze MT, Amankulor NM

Chitinase-3-like 1 protein complexes modulate macrophage-mediated immune suppression in glioblastoma.
The Journal of clinical investigation. 2021 Aug 16;131(16); Authors: Chen A, Jiang Y, Li Z, Wu L, Santiago U, Zou H, Cai C, Sharma V, Guan Y, McCarl LH, Ma J, Wu YL, Michel J, Shi Y, Konnikova L, Amankulor NM, Zinn PO, Kohanbash G, Agnihotri S, Lu S, Lu X, Sun D, Gittes GK, Wang Q, Xiao X, Yimlamai D, Pollack IF, Camacho CJ, Hu B

Re-evaluating Biopsy for Recurrent Glioblastoma: A Position Statement by the Christopher Davidson Forum Investigators.
Neurosurgery. 2021 Jun 15;89(1):129-132; Authors: Nduom EK, Gephart MH, Chheda MG, Suva ML, Amankulor N, Battiste JD, Campian JL, Dacey RG, Das S, Fecci PE, Hadjipanayis CG, Hoang KB, Jalali A, Orringer D, Patel AJ, Placantonakis D, Rodriguez A, Yang I, Yu JS, Zipfel GJ, Dunn GP, Leuthardt EC, Kim AH

TIGIT and PD-1 Immune Checkpoint Pathways Are Associated With Patient Outcome and Anti-Tumor Immunity in Glioblastoma.
Frontiers in immunology. 2021;12:637146 Epub 2021 May 7; Authors: Raphael I, Kumar R, McCarl LH, Shoger K, Wang L, Sandlesh P, Sneiderman CT, Allen J, Zhai S, Campagna ML, Foster A, Bruno TC, Agnihotri S, Hu B, Castro BA, Lieberman FS, Broniscer A, Diaz AA, Amankulor NM, Rajasundaram D, Pollack IF, Kohanbash G

Associations of meningioma molecular subgroup and tumor recurrence.
Neuro-oncology. 2021 May 5;23(5):783-794; Authors: Youngblood MW, Miyagishima DF, Jin L, Gupte T, Li C, Duran D, Montejo JD, Zhao A, Sheth A, Tyrtova E, Özduman K, Iacoangeli F, Peyre M, Boetto J, Pease M, Avşar T, Huttner A, Bilguvar K, Kilic T, Pamir MN, Amankulor N, Kalamarides M, Erson-Omay EZ, Günel M, Moliterno J

Oncolytic HSV Vectors and Anti-Tumor Immunity.
Current issues in molecular biology. 2021;41:381-468 Epub 2020 Sep 17; Authors: Glorioso JC, Cohen JB, Goins WF, Hall B, Jackson JW, Kohanbash G, Amankulor N, Kaur B, Caligiuri MA, Chiocca EA, Holland EC, Quéva C

A contemporary update on glioblastoma: molecular biology, current management, and a vision towards bio-adaptable personalized care.
Journal of neuro-oncology. 2021 Jan;151(2):103-112 Epub 2021 Jan 4; Authors: Habib A, Pease M, Kodavali CV, Amankulor N, Zinn PO

Long-term control of leptomeningeal disease after radiation therapy and nivolumab in a metastatic melanoma patient.
Immunotherapy. 2020 Aug;12(11):763-769 Epub 2020 Jun 22; Authors: Wu RC, Newman W, Patanowitz L, Branstetter BF, Amankulor N, Tarhini AA

Blockade of Cell Volume Regulatory Protein NKCC1 Increases TMZ-Induced Glioma Apoptosis and Reduces Astrogliosis.
Molecular cancer therapeutics. 2020 Jul;19(7):1550-1561 Epub 2020 May 11; Authors: Luo L, Guan X, Begum G, Ding D, Gayden J, Hasan MN, Fiesler VM, Dodelson J, Kohanbash G, Hu B, Amankulor NM, Jia W, Castro MG, Sun B, Sun D

Correlations between genomic subgroup and clinical features in a cohort of more than 3000 meningiomas.
Journal of neurosurgery. 2020 Nov 1;133(5):1345-1354 Epub 2019 Oct 25; Authors: Youngblood MW, Duran D, Montejo JD, Li C, Omay SB, Özduman K, Sheth AH, Zhao AY, Tyrtova E, Miyagishima DF, Fomchenko EI, Hong CS, Clark VE, Riche M, Peyre M, Boetto J, Sohrabi S, Koljaka S, Baranoski JF, Knight J, Zhu H, Pamir MN, Avşar T, Kilic T, Schramm J, Timmer M, Goldbrunner R, Gong Y, Bayri Y, Amankulor N, Hamilton RL, Bilguvar K, Tikhonova I, Tomak PR, Huttner A, Simon M, Krischek B, Kalamarides M, Erson-Omay EZ, Moliterno J, Günel M

GBM-Targeted oHSV Armed with Matrix Metalloproteinase 9 Enhances Anti-tumor Activity and Animal Survival.
Molecular therapy oncolytics. 2019 Dec 20;15:214-222 Epub 2019 Oct 24; Authors: Sette P, Amankulor N, Li A, Marzulli M, Leronni D, Zhang M, Goins WF, Kaur B, Bolyard C, Cripe TP, Yu J, Chiocca EA, Glorioso JC, Grandi P

Identification of Novel RAS Signaling Therapeutic Vulnerabilities in Diffuse Intrinsic Pontine Gliomas.
Cancer research. 2019 Aug 15;79(16):4026-4041 Epub 2019 Jun 14; Authors: Koncar RF, Dey BR, Stanton AJ, Agrawal N, Wassell ML, McCarl LH, Locke AL, Sanders L, Morozova-Vaske O, Myers MI, Hamilton RL, Carcaboso AM, Kohanbash G, Hu B, Amankulor NM, Felker J, Kambhampati M, Nazarian J, Becher OJ, James CD, Hashizume R, Broniscer A, Pollack IF, Agnihotri S

Neoadjuvant Anti-PD-1 Immunotherapy Leads to Survival Benefit in Recurrent Glioblastoma.
Neurosurgery. 2019 Aug 1;85(2):E190-E191; Authors: Newman WC, Amankulor NM

Arming oHSV with ULBP3 drives abscopal immunity in lymphocyte-depleted glioblastoma.
JCI insight. 2019 Jul 11;4(13); Authors: Wirsching HG, Zhang H, Szulzewsky F, Arora S, Grandi P, Cimino PJ, Amankulor N, Campbell JS, McFerrin L, Pattwell SS, Ene C, Hicks A, Ball M, Yan J, Zhang J, Kumasaka D, Pierce RH, Weller M, Finer M, Quéva C, Glorioso JC, Houghton AM, Holland EC

Elevated Na/H exchanger 1 (SLC9A1) emerges as a marker for tumorigenesis and prognosis in gliomas.
Journal of experimental & clinical cancer research : CR. 2018 Oct 17;37(1):255; Authors: Guan X, Luo L, Begum G, Kohanbash G, Song Q, Rao A, Amankulor N, Sun B, Sun D, Jia W

Long-Term Survivorship Following Stereotactic Radiosurgery Alone for Brain Metastases: Risk of Intracranial Failure and Implications for Surveillance and Counseling.
Neurosurgery. 2018 Aug 1;83(2):203-209; Authors: Gogineni E, Vargo JA, Glaser SM, Flickinger JC, Burton SA, Engh JA, Amankulor NM, Beriwal S, Quinn AE, Ozhasoglu C, Heron DE

Stereotactic body radiation therapy for benign spine tumors: is dose de-escalation appropriate?
Journal of neurosurgery. Spine. 2018 Aug;29(2):220-225 Epub 2018 May 25; Authors: Kalash R, Glaser SM, Flickinger JC, Burton S, Heron DE, Gerszten PC, Engh JA, Amankulor NM, Vargo JA

Long-Term Outcomes After Stereotactic Radiosurgery for Spine Metastases: Radiation Dose-Response for Late Toxicity.
International journal of radiation oncology, biology, physics. 2018 Jul 1;101(3):602-609 Epub 2018 Mar 6; Authors: Ling DC, Flickinger JC, Burton SA, Heron DE, Quinn AE, Bejjani GK, Engh JA, Gerszten PC, Amankulor NM, Vargo JA

Core Entrustable Professional Activities in Clinical Pharmacology for Entering Residency: Value of Interprofessional Health-Care Teams in Medication Prescribing and Medication Error Prevention.
Journal of clinical pharmacology. 2018 Jul;58(7):843-848 Epub 2018 May 3; Authors: Cohen LJ, Donnenberg VS, Wiernik PH, Newman WC, Amankulor N

The Utility of Early Postoperative Head Computed Tomography in Brain Tumor Surgery: A Retrospective Analysis of 755 Cases.
World neurosurgery. 2018 Mar;111:e206-e212 Epub 2017 Dec 16; Authors: Alkhalili K, Zenonos G, Tataryn Z, Amankulor N, Engh J

Single-cell profiling of human gliomas reveals macrophage ontogeny as a basis for regional differences in macrophage activation in the tumor microenvironment.
Genome biology. 2017 Dec 20;18(1):234; Authors: Müller S, Kohanbash G, Liu SJ, Alvarado B, Carrera D, Bhaduri A, Watchmaker PB, Yagnik G, Di Lullo E, Malatesta M, Amankulor NM, Kriegstein AR, Lim DA, Aghi M, Okada H, Diaz A

Genomic analysis of 220 CTCLs identifies a novel recurrent gain-of-function alteration in RLTPR (p.Q575E).
Blood. 2017 Sep 21;130(12):1430-1440 Epub 2017 Jul 10; Authors: Park J, Yang J, Wenzel AT, Ramachandran A, Lee WJ, Daniels JC, Kim J, Martinez-Escala E, Amankulor N, Pro B, Guitart J, Mendillo ML, Savas JN, Boggon TJ, Choi J

Phase I/II Trial of Combination of Temozolomide Chemotherapy and Immunotherapy With Fusions of Dendritic and Glioma Cells in Patients With Glioblastoma.
Neurosurgery. 2017 Jul 1;81(1):N11; Authors: Kim WJ, Newman WC, Amankulor NM

BRCA1-Regulated RRM2 Expression Protects Glioblastoma Cells from Endogenous Replication Stress and Promotes Tumorigenicity.
Neurosurgery. 2017 May 1;80(5):N34; Authors: Newman WC, Kim WJ, Amankulor NM

Mutant IDH1 regulates the tumor-associated immune system in gliomas.
Genes & development. 2017 Apr 15;31(8):774-786 Epub 2017 May 2; Authors: Amankulor NM, Kim Y, Arora S, Kargl J, Szulzewsky F, Hanke M, Margineantu DH, Rao A, Bolouri H, Delrow J, Hockenbery D, Houghton AM, Holland EC

Isocitrate dehydrogenase mutations suppress STAT1 and CD8+ T cell accumulation in gliomas.
The Journal of clinical investigation. 2017 Apr 3;127(4):1425-1437 Epub 2017 Mar 20; Authors: Kohanbash G, Carrera DA, Shrivastav S, Ahn BJ, Jahan N, Mazor T, Chheda ZS, Downey KM, Watchmaker PB, Beppler C, Warta R, Amankulor NA, Herold-Mende C, Costello JF, Okada H

Focused Ultrasound Enhances Central Nervous System Delivery of Bevacizumab for Malignant Glioma Treatment.
Neurosurgery. 2016 Dec;79(6):N12; Authors: Newman WC, Amankulor NA

IDH mutant gliomas escape natural killer cell immune surveillance by downregulation of NKG2D ligand expression.
Neuro-oncology. 2016 Oct;18(10):1402-12 Epub 2016 Apr 25; Authors: Zhang X, Rao A, Sette P, Deibert C, Pomerantz A, Kim WJ, Kohanbash G, Chang Y, Park Y, Engh J, Choi J, Chan T, Okada H, Lotze M, Grandi P, Amankulor N

Control of Glioblastoma Tumorigenesis by Feed-Forward Cytokine Signaling.
Neurosurgery. 2016 Oct;79(4):N9-N10; Authors: Newman WC, Amankulor NA

Hyalinizing Clear Cell Carcinoma with Biopsy-Proven Spinal Metastasis: Case Report and Review of Literature.
World neurosurgery. 2016 Jun;90:699.e7-699.e10 Epub 2016 Feb 6; Authors: Newman WC, Williams L, Duvvuri U, Clump DA 2nd, Amankulor N

Targeted Treatment of Experimental Spinal Cord Glioma With Dual Gene-Engineered Human Neural Stem Cells.
Neurosurgery. 2016 Jun;78(6):N15-7; Authors: Newman WC, Amankulor NA

Targeted next-generation sequencing panel (GlioSeq) provides comprehensive genetic profiling of central nervous system tumors.
Neuro-oncology. 2016 Mar;18(3):379-87 Epub 2015 Dec 17; Authors: Nikiforova MN, Wald AI, Melan MA, Roy S, Zhong S, Hamilton RL, Lieberman FS, Drappatz J, Amankulor NM, Pollack IF, Nikiforov YE, Horbinski C

Tumor bed radiosurgery following resection and prior stereotactic radiosurgery for locally persistent brain metastasis.
Frontiers in oncology. 2015;5:84 Epub 2015 Apr 8; Authors: Holt DE, Gill BS, Clump DA, Leeman JE, Burton SA, Amankulor NM, Engh JA, Heron DE

Ommaya reservoir with ventricular catheter placement for chemotherapy with frameless and pinless electromagnetic surgical neuronavigation.
Clinical neurology and neurosurgery. 2015 Mar;130:61-6 Epub 2015 Jan 5; Authors: Weiner GM, Chivukula S, Chen CJ, Ding D, Engh JA, Amankulor N

Postoperative stereotactic radiosurgery to the resection cavity for large brain metastases: clinical outcomes, predictors of intracranial failure, and implications for optimal patient selection.
Neurosurgery. 2015 Feb;76(2):150-6; discussion 156-7; quiz 157; Authors: Ling DC, Vargo JA, Wegner RE, Flickinger JC, Burton SA, Engh J, Amankulor N, Quinn AE, Ozhasoglu C, Heron DE

Induction of robust type-I CD8+ T-cell responses in WHO grade 2 low-grade glioma patients receiving peptide-based vaccines in combination with poly-ICLC.
Clinical cancer research : an official journal of the American Association for Cancer Research. 2015 Jan 15;21(2):286-94 Epub 2014 Nov 25; Authors: Okada H, Butterfield LH, Hamilton RL, Hoji A, Sakaki M, Ahn BJ, Kohanbash G, Drappatz J, Engh J, Amankulor N, Lively MO, Chan MD, Salazar AM, Shaw EG, Potter DM, Lieberman FS

Use of miRNA response sequences to block off-target replication and increase the safety of an unattenuated, glioblastoma-targeted oncolytic HSV.
Molecular therapy : the journal of the American Society of Gene Therapy. 2015 Jan;23(1):99-107 Epub 2014 Sep 9; Authors: Mazzacurati L, Marzulli M, Reinhart B, Miyagawa Y, Uchida H, Goins WF, Li A, Kaur B, Caligiuri M, Cripe T, Chiocca EA, Amankulor N, Cohen JB, Glorioso JC, Grandi P

The SHH/Gli pathway is reactivated in reactive glia and drives proliferation in response to neurodegeneration-induced lesions.
Glia. 2014 Oct;62(10):1595-607 Epub 2014 Jun 4; Authors: Pitter KL, Tamagno I, Feng X, Ghosal K, Amankulor N, Holland EC, Hambardzumyan D

The incidence and patterns of hardware failure after separation surgery in patients with spinal metastatic tumors.
The spine journal : official journal of the North American Spine Society. 2014 Sep 1;14(9):1850-9 Epub 2013 Nov 8; Authors: Amankulor NM, Xu R, Iorgulescu JB, Chapman T, Reiner AS, Riedel E, Lis E, Yamada Y, Bilsky M, Laufer I

Osteopontin-CD44 signaling in the glioma perivascular niche enhances cancer stem cell phenotypes and promotes aggressive tumor growth.
Cell stem cell. 2014 Mar 6;14(3):357-69; Authors: Pietras A, Katz AM, Ekström EJ, Wee B, Halliday JJ, Pitter KL, Werbeck JL, Amankulor NM, Huse JT, Holland EC

Resection of glioma in an fMRI-defined "split" Broca's area.
Neurocase. 2014;20(5):481-6 Epub 2013 Aug 13; Authors: Kim JH, Amankulor NM, Peck KK, Brennan N, Gutin PH, Holodny AI

GM-CSF promotes the immunosuppressive activity of glioma-infiltrating myeloid cells through interleukin-4 receptor-α.
Cancer research. 2013 Nov 1;73(21):6413-23 Epub 2013 Sep 12; Authors: Kohanbash G, McKaveney K, Sakaki M, Ueda R, Mintz AH, Amankulor N, Fujita M, Ohlfest JR, Okada H

Stereotactic laser induced thermotherapy (LITT): a novel treatment for brain lesions regrowing after radiosurgery.
Journal of neuro-oncology. 2013 Jul;113(3):495-503 Epub 2013 May 16; Authors: Torres-Reveron J, Tomasiewicz HC, Shetty A, Amankulor NM, Chiang VL

A novel cranioplasty technique incorporating cancellous femoral bone and recombinant bone morphogenic protein 2.
The Journal of craniofacial surgery. 2012 Jul;23(4):1083-6; Authors: Wang F, Hoang D, Medvecky M, Amankulor N, Teng E, Narayan D

Astrocyte-specific expression patterns associated with the PDGF-induced glioma microenvironment.
PloS one. 2012;7(2):e32453 Epub 2012 Feb 29; Authors: Katz AM, Amankulor NM, Pitter K, Helmy K, Squatrito M, Holland EC

Extracranial carotid plaque length and parent vessel diameter significantly affect baseline ipsilateral intracranial blood flow.
Neurosurgery. 2011 Oct;69(4):767-73; discussion 773; Authors: Douglas AF, Christopher S, Amankulor N, Din R, Poullis M, Amin-Hanjani S, Ghogawala Z

Sonic hedgehog pathway activation is induced by acute brain injury and regulated by injury-related inflammation.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 2009 Aug 19;29(33):10299-308; Authors: Amankulor NM, Hambardzumyan D, Pyonteck SM, Becher OJ, Joyce JA, Holland EC

Modeling Adult Gliomas Using RCAS/t-va Technology.
Translational oncology. 2009 May;2(2):89-95; Authors: Hambardzumyan D, Amankulor NM, Helmy KY, Becher OJ, Holland EC

Cerebrovascular disease associated with Aarskog-Scott syndrome.
Neuroradiology. 2007 May;49(5):457-61 Epub 2007 Feb 10; Authors: Diluna ML, Amankulor NM, Johnson MH, Gunel M

Krev1 interaction trapped-1/cerebral cavernous malformation-1 protein expression during early angiogenesis.
Journal of neurosurgery. 2004 May;100(5 Suppl Pediatrics):481-7; Authors: Guzeloglu-Kayisli O, Kayisli UA, Amankulor NM, Voorhees JR, Gokce O, DiLuna ML, Laurans MS, Luleci G, Gunel M

KRIT1/cerebral cavernous malformation 1 protein localizes to vascular endothelium, astrocytes, and pyramidal cells of the adult human cerebral cortex.
Neurosurgery. 2004 Apr;54(4):943-9; discussion 949; Authors: Guzeloglu-Kayisli O, Amankulor NM, Voorhees J, Luleci G, Lifton RP, Gunel M