Faculty

David A. Hill, MD, PhD, FAAP, FACAAI, FAAAI

faculty photo
Assistant Professor of Pediatrics
Department: Pediatrics
Graduate Group Affiliations

Contact information
Children's Hospital of Philadelphia
Division of Allergy and Immunology
Department of Pediatrics
Abramson Pediatric Research Center, Room 1208B
3615 Civic Center Blvd.
Philadelphia, PA 19104
Office: 215-590-2549
Fax: 267-426-0363
Lab: 267-426-7777
Education:
BS (Biological Sciences, with honors)
Carnegie Mellon University, 2005.
PhD (Cell and Molecular Biology)
University of Pennsylvania School of Medicine, David Artis Lab, 2011.
MD (Medicine)
University of Pennsylvania School of Medicine, 2013.
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Description of Clinical Expertise

Food allergy, eosinophilic esophagitis, obesity-associated asthma.

Description of Research Expertise

The Hill Lab seeks to understand the causes of allergy and obesity, as well as the immunometabolic overlap between these two highly prevalent conditions. We use the unique approach of letting clinical data guide our mechanistic studies of the innate and adaptive arms of the immune system in transgenic and gene-targeted mice and patient samples. Our goal is to translate our discoveries into the development of novel preventative, diagnostic, and therapeutic approaches for human disease.

Selected Publications

Capucilli P, Hill DA: Effects of oral immunotherapy on immune tolerance. Annals of Allergy, Asthma & Immunology 129(6): 659-660, Dec 2022.

Sterling JK, Baumann B, Foshe S, Voigt A, Guttha S, Alnemri A, McCright SJ, Li M, Zauhar RJ, Montezuma SR, Kapphahn RJ, Chavali VRM, Hill DA, Ferrington DA, Stambolian D, Mullins RF, Merrick D, and Dunaief JL: Inflammatory adipose activates a nutritional immunity pathway leading to retinal dysfunction. Cell Reports 39(11): 110942, Jun 2022.

Spergel BS, Ruffner MA, Godwin B, Liacouras CA, Cianferoni A, Gober L, Hill DA, Brown-Whitehorn TA, Chaiboonma K, Aceves SA, Muir AM, Spergel JM: Improvement in Eosinophilic Esophagitis when using Dupilumab for other Indications or Compassionate Use. Annals of Allergy, Asthma, and Immunology 128(5): 589-593, May 2022.

Hill DA: The importance of using core outcome measures during therapeutic studies of eosinophilic esophagitis. The Journal of Allergy and Clinical Immunology 149(2): 541-542, Feb 2022.

Gabryszewski SJ, Dudley J, Grundmeier RW, Fiks AG, Hill DA: Analysis of a Multi-State Pediatric Birth Cohort Reveals Incidence of Pediatric Allergy. American Academy of Allergy, Asthma & Immunology Annual Meeting, Phoenix, AZ; The Journal of Allergy and Clinical Immunology 149(2): AB227, Feb 2022 Notes: Oral presentation.

Rodríguez-López EM, Dilollo J, Eisenlohr L, Hill DA: Esophageal Epithelial Cells Present Antigen on MHCII in an IFNy and Promoter IV-Dependent Manner. American Academy of Allergy, Asthma & Immunology Annual Meeting, Phoenix, AZ; The Journal of Allergy and Clinical Immunology 149(2): AB136, Feb 2022 Notes: Oral presentation.

Sayed S, Diwadkar AR, Dudley JW, O’Brien J, Dvorin D, Kenyon CK, Himes BE, Hill DA*, Henrickson SE: COVID-19 Pandemic-Related Reductions in Pediatric Asthma Exacerbations Corresponded with an Overall Decrease in Respiratory Viral Infections. The Journal of Allergy and Clinical Immunology: In Practice 10(1): 91-99, Jan 2022.

Dilollo J, Pratt M, Rodriguez-Lopez EM, Spergel JM, Hill DA: Antigenicity and HLA Locus Restriction of Milk Proteins in Eosinophilic Esophagitis. Gordon Research Seminar in Food Allergy, Ventura CA. Jan 2022 Notes: Oral presentation. Cancelled due to COVID.

Gabryszewski SJ, Hill DA, Spergel JM: The Atopic March. World Allergy Association In Press 2022.

Vakili S, Paneru B, Guerrier CM, Miller J, Baumrin E, Forrestel A, Lynn K, Frank I, Lo Re V, Collman RG, and Hill DA: Altered adipose tissue macrophage populations in people with HIV on integrase inhibitor-containing ART. AIDS In Press 2022.

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Last updated: 01/10/2023
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