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Joel Babdor, PhD
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Assistant Professor of Pharmacology
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Department: Systems Pharmacology and Translational Therapeutics
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Contact information
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University of Pennsylvania Perelman School of Medicine
23 3600 Civic Center Boulevard
29 12-114
Philadelphia, PA 19104
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23 3600 Civic Center Boulevard
29 12-114
Philadelphia, PA 19104
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Education:
21 7 BS 14 (Biology) c
35 Paris-EST Creteil University, 2008.
21 7 MS 17 (Immunology) c
2b Sorbone University, 2010.
21 8 PhD 28 (Immunology and Cell Biology) c
2c University of Paris, 2015.
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Permanent link21 7 BS 14 (Biology) c
35 Paris-EST Creteil University, 2008.
21 7 MS 17 (Immunology) c
2b Sorbone University, 2010.
21 8 PhD 28 (Immunology and Cell Biology) c
2c University of Paris, 2015.
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212 The Precision Immunology & Microbiome Medicine lab aims at understanding immune health, through a multi-systems approach that explores the dialogue between the human immune system and the microbial exposome. We use high-throughput, high-dimensional profiling approaches and multimodal computational methods to study clinical and model system data. Our long-term goal is to better define immune health and contribute to the development of precision microbiome-medicine therapies to improve immune interventions for patients.
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Description of Research Expertise
24 Research Interests:212 The Precision Immunology & Microbiome Medicine lab aims at understanding immune health, through a multi-systems approach that explores the dialogue between the human immune system and the microbial exposome. We use high-throughput, high-dimensional profiling approaches and multimodal computational methods to study clinical and model system data. Our long-term goal is to better define immune health and contribute to the development of precision microbiome-medicine therapies to improve immune interventions for patients.
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f7 Woitowich NC, Hengel SR, Solis C, Vilgalys TP, Babdor J, Tyrrell DJ.: Analysis of NIH K99/R00 Awards and the Career Progression of Awardees. bioRxiv Dec 2023 Notes: Preprint.
f3 Escalante V, Nayak RR, Noecker C, Babdor J, Spitzer M, Deutschbauer AM, Turnbaugh PJ.: Simvastatin induces human gut bacterial cell surface genes. Mol Microbiol Sep 2023.
279 Rossignol J, Belaid Z, Fouquet G, Guillem F, Rignault R, Milpied P, Renand A, Coman T, D’Aveni M, Dussiot M, Colin E, Levy J, Carvalho C, Goudin N, Cagnard N, Côté F, Babdor J, Bhukhai K, Polivka L, Bigorgne A, Halse H, Marabelle A, Mouraud S, Lepelletier Y, Maciel T, Rubio MT, Heron D, Robert C, Girault I, Lebeherec D, Scoazec JY, Moura I, Condon L, Weimershaus M, Pages F, Davoust J, Gross D, Hermine O: Neuropilin-1 cooperates with PD-1 in CD8+ T-cells predicting outcomes in melanoma patients treated with anti-PD1. IScience 25(6): 104353, June 2022.
27c Rossignol J, Belaid Z, Fouquet G, Guillem F, Rignault R, Milpied P, Renand A, Coman T, D'Aveni M, Dussiot M, Colin E, Levy J, Carvalho C, Goudin N, Cagnard N, Côté F, Babdor J, Bhukhai K, Polivka L, Bigorgne AE, Halse H, Marabelle A, Mouraud S, Lepelletier Y, Maciel TT, Rubio MT, Heron D, Robert C, Girault I, Lebeherec D, Scoazec JY, Moura I, Condon L, Weimershaus M, Pages F, Davoust J, Gross D, Hermine O.: Neuropilin-1 cooperates with PD-1 in CD8(+) T cells predicting outcomes in melanoma patients treated with anti-PD1. iScience 25(6): 104353, May 2022.
193 Ishiyama K, Arakawa-Hoyt J, Aguilar OA, Damm I, Towfighi P, Sigdel T, Tamaki S, Babdor J, Spitzer MH, Reed EF, Sarwal MM, Lanier LL and CMV Systems Immunobiology Group: Mass cytometry reveals single-cell kinetics of cytotoxic lymphocyte evolution in CMV-infected renal transplant patients. PNAS 119(8): e2116588119, February 2022.
1e4 Sanders L, Yang J, Scott R, Qutub A, Martin H, Berrios D, Hastings J, Rask J, Mackintosh, Graham & Hoarfrost, Adrienne & Chalk, Stuart & Kalantari, John & Khezeli, Kia & Antonsen, Erik & Babdor, Joel & Barker, Richard & Baranzini S, Beheshti A, Delgado-Aparicio G, Costes S.: Beyond Low Earth Orbit: Biological Research, Artificial Intelligence, and Self-Driving Labs. arXiv preprint 2112: 12582, December 2021.
149 Babdor J, Fan AC, Wane M, Mbiribindi B, Mobley AS, Noel JC, Kouame E.: Black In Immuno: harnessing social media and digital platforms to connect the dots. Nat Rev Immunol 21(12): 756-757, December 2021 Notes: DOI:https://doi.org/10.1038/s41577-021-00645-5.
1ae Scott R, Antonsen E, Sanders L, Hastings J, Park S, Mackintosh G, Reynolds R, Hoarfrost A, Sawyer A, Greene C, Glicksberg B, Theriot C, Berrios D, Miller J, Babdor J, Barker R, Baranzini S, Beheshti A, Chalk S, Costes S.: Beyond Low Earth Orbit: Biomonitoring, Artificial Intelligence, and Precision Space Health. arXiv preprint 2112: 12554, December 2021.
155 Kouame E, Noel JC, Wane M, Babdor J, Caslin HL, Fan A, Mbiribindi B, Sattler S, Mobley AS: Black in Immuno Week: Who We Are, What We Did, and Why It Matters. The Journal of Immunology 207(8): 1941-1947, October 2021 Notes: DOI:https://doi.org/10.4049/jimmunol.2100667.
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Selected Publications
1cc Joel Babdor, Ravi K. Patel, Brittany Davidson, Cecilia Noecker, Maha Rahim, Jordan E. Bisanz, Iliana Tenvooren, Diana Marquez, Maria Calvo11Calvo, Vrinda Johri, Elizabeth McCarthy, Avneet Shaheed, Christina Ekstrand, Allison M. Weakley, Feiqiao B. Yu, Oliver Fiehn, Peter J. Turnbaugh, Alexis J. Combes, Gabriela K. Fragiadakis, Matthew H. Spitzer: Coordinated variation in the immune systems and microbiomes 8c of healthy humans is linked to tonic interferon states. BioRxiv Page: DOI: 10.1101/2024.11.27.625750, December 2024.f7 Woitowich NC, Hengel SR, Solis C, Vilgalys TP, Babdor J, Tyrrell DJ.: Analysis of NIH K99/R00 Awards and the Career Progression of Awardees. bioRxiv Dec 2023 Notes: Preprint.
f3 Escalante V, Nayak RR, Noecker C, Babdor J, Spitzer M, Deutschbauer AM, Turnbaugh PJ.: Simvastatin induces human gut bacterial cell surface genes. Mol Microbiol Sep 2023.
279 Rossignol J, Belaid Z, Fouquet G, Guillem F, Rignault R, Milpied P, Renand A, Coman T, D’Aveni M, Dussiot M, Colin E, Levy J, Carvalho C, Goudin N, Cagnard N, Côté F, Babdor J, Bhukhai K, Polivka L, Bigorgne A, Halse H, Marabelle A, Mouraud S, Lepelletier Y, Maciel T, Rubio MT, Heron D, Robert C, Girault I, Lebeherec D, Scoazec JY, Moura I, Condon L, Weimershaus M, Pages F, Davoust J, Gross D, Hermine O: Neuropilin-1 cooperates with PD-1 in CD8+ T-cells predicting outcomes in melanoma patients treated with anti-PD1. IScience 25(6): 104353, June 2022.
27c Rossignol J, Belaid Z, Fouquet G, Guillem F, Rignault R, Milpied P, Renand A, Coman T, D'Aveni M, Dussiot M, Colin E, Levy J, Carvalho C, Goudin N, Cagnard N, Côté F, Babdor J, Bhukhai K, Polivka L, Bigorgne AE, Halse H, Marabelle A, Mouraud S, Lepelletier Y, Maciel TT, Rubio MT, Heron D, Robert C, Girault I, Lebeherec D, Scoazec JY, Moura I, Condon L, Weimershaus M, Pages F, Davoust J, Gross D, Hermine O.: Neuropilin-1 cooperates with PD-1 in CD8(+) T cells predicting outcomes in melanoma patients treated with anti-PD1. iScience 25(6): 104353, May 2022.
193 Ishiyama K, Arakawa-Hoyt J, Aguilar OA, Damm I, Towfighi P, Sigdel T, Tamaki S, Babdor J, Spitzer MH, Reed EF, Sarwal MM, Lanier LL and CMV Systems Immunobiology Group: Mass cytometry reveals single-cell kinetics of cytotoxic lymphocyte evolution in CMV-infected renal transplant patients. PNAS 119(8): e2116588119, February 2022.
1e4 Sanders L, Yang J, Scott R, Qutub A, Martin H, Berrios D, Hastings J, Rask J, Mackintosh, Graham & Hoarfrost, Adrienne & Chalk, Stuart & Kalantari, John & Khezeli, Kia & Antonsen, Erik & Babdor, Joel & Barker, Richard & Baranzini S, Beheshti A, Delgado-Aparicio G, Costes S.: Beyond Low Earth Orbit: Biological Research, Artificial Intelligence, and Self-Driving Labs. arXiv preprint 2112: 12582, December 2021.
149 Babdor J, Fan AC, Wane M, Mbiribindi B, Mobley AS, Noel JC, Kouame E.: Black In Immuno: harnessing social media and digital platforms to connect the dots. Nat Rev Immunol 21(12): 756-757, December 2021 Notes: DOI:https://doi.org/10.1038/s41577-021-00645-5.
1ae Scott R, Antonsen E, Sanders L, Hastings J, Park S, Mackintosh G, Reynolds R, Hoarfrost A, Sawyer A, Greene C, Glicksberg B, Theriot C, Berrios D, Miller J, Babdor J, Barker R, Baranzini S, Beheshti A, Chalk S, Costes S.: Beyond Low Earth Orbit: Biomonitoring, Artificial Intelligence, and Precision Space Health. arXiv preprint 2112: 12554, December 2021.
155 Kouame E, Noel JC, Wane M, Babdor J, Caslin HL, Fan A, Mbiribindi B, Sattler S, Mobley AS: Black in Immuno Week: Who We Are, What We Did, and Why It Matters. The Journal of Immunology 207(8): 1941-1947, October 2021 Notes: DOI:https://doi.org/10.4049/jimmunol.2100667.
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