Roy Hoshi Hamilton, MD, MS, FAAN, FANA

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Associate Professor of Neurology
Department: Neurology
Graduate Group Affiliations

Contact information
Goddard Laboratories, Room 518
University of Pennsylvania
3710 Hamilton Walk
Philadelphia, PA 19104
Office: 215-573-7065
Fax: 215-898-1982
B.A. (Psychology, magna cum laude)
Harvard University, 1995.
M.D. (Medicine, cum laude)
Harvard Medical School, 2001.
M.S. (Health Sciences and Technology)
Massachusetts Institute of Technology , 2001.
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Description of Research Expertise

My research focus is on the characteristics and limits of functional neuroplasticity in the adult human brain. I investigate how the brain reorganizes itself in response to injury, and whether or not it is possible to enhance the brain’s potential for reorganization in order to speed rehabilitation using noninvasive electrical or magnetic brain stimulation. A second area of interest for me is on the use of noninvasive brain stimulation to elucidate and enhance mechanisms of cognition in healthy individuals, and the biological, social, and ethical implications of neural enhancement.

Selected Publications

Schwab, P.J., Miller, A. Raphail, A., Levine, A., Haslam, C., Coslett, H.B., Hamilton, R.H.: Virtual reality tools for assessing unilateral spatial neglect: A novel opportunity for data collection. Journal of Visual Experimentation 169, Mar 2021.

Shah-Basak, P., Harvey, D.Y., Parchure, S., Faseyitan, O., Sacchetti, D., Ahmed, A., Thiam, A., Lohoff, F.W., Hamilton, R.H.: Brain-derived neurotrophic factor polymorphism influences response to single-pulse transcranial magnetic stimulation at rest. Neuromodulation: Technology at the Neural Interface Oct 2020 Notes: Online ahead of print.

Nissim, N.R., Moberg, P.J., Hamilton, R.H. : Efficacy of noninvasive brain stimulation (tDCS or TMS) paired with language therapy in the treatment of primary progressive aphasia: an exploratory meta-analysis. Brain Sciences 10(9): E597, August 2020.

Ling, S., Raine, A., Choy, O., Hamilton, R. : The effect of prefrontal cortical stimulation on aggressive and antisocial behavior: A double-Blind, stratified, randomized, sham-Controlled, parallel-group trial. Journal of Experimental Criminology 16: 367–387, May 2020.

Markman, T.M., Hamilton, R.H., Marchlinski, F.E., Nazarian, S.: Case series of transcutaneous magnetic stimulation for ventricular tachycardia storm. Journal of the American Medical Association (JAMA) 323(21): 2200-2202, May 2020.

Coronel, J.C., O'Donnell, M.B., Beard, E.C., Hamilton, R.H., Falk, E.B.: Evaluating didactic and exemplar information: Non-invasive brain stimulation reveals message-processing mechanisms. Communication Research Sept 2019.

Harvey, D.Y., DeLoretta, L., Wurzman, R., Sacchetti, D., Ahmed, A., Thiam, A., Lohoff, F., Faseyitan, O., Hamilton, R.H. : BDNF polymorphism predicts plasticity in motor cortex following continuous theta burst stimulation (published proceedings). Brain Stimulation 12(4), Jul-Aug 2019.

Petrovsky, D.V., Johnson, J.K., Tkacs, N., Mechanic-Hamilton, D., Hamilton, R. H., Cacchione, P.Z. : Musical and cognitive abilities in older adults with mild cognitive impairment. Psychology of Music May 2019.

Harvey, D.Y., Mass, J.A., Shah-Basak, P.P. Wurzman, R., Faseyitan, O., Sacchetti, D.L., DeLoretta, L., Hamilton, R.H.: Continuous theta burst stimulation over right pars triangularis facilitates naming abilities in chronic post-stroke aphasia by enhancing phonological access. Brain and Language 192: 25-34, May 2019.

Hosseini, M., McConathey, E.M., Ungrady, M. Grossman, M., Coslett, H.B., Hamilton, R.H. : Transcranial direct current stimulation mediates improvements in verbal fluency for patients with primary progressive aphasia (published proceedings). Brain Stimulation 12: e69-e70, Mar 2019.

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Last updated: 05/12/2021
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