Max B. Kelz, MD PhD

faculty photo
Anesthesia Distinguished Professor
Department: Anesthesiology and Critical Care
Graduate Group Affiliations

Contact information
3620 Hamilton Walk,
John Morgan Building - Room 334
Philadelphia, PA 19104
Office: 215 573-8208
Fax: 215 349-5078
Lab: 215 898-8929
BS (Molecular Biophysics and Biochemistry)
Yale University, 1993.
MS (Molecular Biophysics and Biochemistry)
Yale University, 1993.
PhD (Neuroscience)
Yale University, 1999.
MD (Medicine)
Yale University, 2000.
Permanent link

Description of Research Expertise

Molecular Mechanisms of Anesthetic Action
Neurobiology of Sleep Wake Regulation
Mouse Genetics
Molecular Biology
Anesthetic pharmacology

Selected Publications

Proekt A and Kelz MB: Explaining anaesthetic hysteresis with effect-site equilibration. Br J Anaesth 126: 265-278, Jan 2021 Notes: Comment in Resisting neural inertia: an exercise in floccinaucinihilipilification? Eleveld DJ, Colin PJ, Absalom AR, Struys MMRF. Br J Anaesth. 2021 Jan;126(1):31-34.

Reitz SL, Wasilczuk AZ, Beh GH, Proekt A, Kelz MB: Activation of Preoptic Tachykinin 1 Neurons Promotes Wakefulness Over Sleep and Volatile Anesthetic-Induced Unconsciousness. Current Biology in press, 2021.

Culley DJ, Kelz MB, Koch CG, Eisenach JC, Neuman MD, Whitlock EL, Robertson RM, Cooper T, Pomerans P: Creation of the Anesthesia Research Council Anesth Analg. 131(4): 1300-1303, Oct 2020.

Wasilczuk AZ, Harrison BA, Kwasniewska P, Ku B, Kelz MB, McKinstry-Wu AR,Proekt A: Resistance to State Transitions is Differentially Modulated by Different Volatile Anaesthetics. Br J Anaesth 125(3): 308-320, Sep 2020.

McKinstry-Wu AR, Proekt A, Kelz MB: Neural Inertia: A Sticky Situation for Anesthesia. J Neurosurg Anesthesiol 32(3): 190-192, July 2020.

Ferreira AL, Correia R, Vide S, Ferreira AD, Kelz MB, Mendes JG, Nunes CS, Amorim P.: Patterns of Hysteresis Between Induction and Emergence of Neuroanesthesia Are Present in Spinal and Intracranial Surgeries. J Neurosurg Anesthesiol. 32(1): 82-89, Jan 2020.

Ramayya AG, Yang AI, Buch VP, Burke JF, Richardson AG, Brandon C, Stein JM, Davis KA, Chen HI, Proekt A, Kelz MB, Litt B, Gold JI, Lucas TH.: Theta synchrony is increased near neural populations that are active when initiating instructed movement. eNeuro 2020.

McKinstry-Wu AR, Wasilczuk AZ, Harrison BA, Bedell VA, Sridharan MJ, Breig JJ, Pack M, Kelz MB, Proekt A: Analysis of Stochastic Fluctuations in Responsiveness is a Critical Step Towards Personalized Anesthesia. eLife 8: e50143, Dec 2019.

Shortal BP, Hickman LB, Mak-McCully RA, Wang W, Brennan C, Ung H, Litt B, Tarnal V, Janke E, Picton P, Blain-Moraes S, Maybrier HR, Muench MR, Lin N, Avidan MS, Mashour GA, McKinstry-Wu AR, Kelz MB, Palanca BJ, Proekt A; ReCCognition Study Group: Duration of EEG suppression does not predict recovery time or degree of cognitive impairment after general anaesthesia in human volunteers. Br J Anaesth 123(2): 206-18, Aug 2019.

Li D, Vlisides PE, Kelz MB, Avidan MS, Mashour GA, ReCCognition Study Group: Dynamic Cortical Connectivity during General Anesthesia in Healthy Volunteers. Anesthesiology 130(6): 870-884, Jun 2019.

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Last updated: 01/26/2021
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