Faculty

Max B. Kelz, MD PhD

faculty photo
Lee A. Fleisher, MD Professor of Anesthesiology and Critical Care
Department: Anesthesiology and Critical Care
Graduate Group Affiliations

Contact information
3620 Hamilton Walk,
John Morgan Building - Room 334
Philadelphia, PA 19104
Office: 215 573-8208
Fax: 215 349-5078
Lab: 215 898-8929
Education:
MS (Molecular Biophysics and Biochemistry)
Yale University, 1993.
BS (Molecular Biophysics and Biochemistry)
Yale University, 1993.
PhD (Neuroscience)
Yale University, 1999.
MD (Medicine)
Yale University, 2000.
Permanent link
 

Description of Research Expertise

Molecular Mechanisms of Anesthetic Action
Neurobiology of Sleep Wake Regulation
Mouse Genetics
Molecular Biology
Anesthetic pharmacology

Selected Publications

Aggarwal A, Luo J, Chung H, Contreras D, Kelz MB, Proekt A.: Neural assemblies coordinated by cortical waves are associated with waking and hallucinatory brain states. Cell Rep 43: 114017, Apr 2024.

Wasilczuk AZ, Rinehart C, Aggarwal A, Stone ME, Mashour GA, Avidan MS, Kelz MB, Proekt A; ReCCognition Study Group.: Hormonal basis of sex differences in anesthetic sensitivity. Proc Natl Acad Sci U S A 121: e2312913120, Jan 2024.

McKinstry-Wu AR, Wasilczuk AZ, Dailey WP, Eckenhoff RG, Kelz MB.: In Vivo Photoadduction of Anesthetic Ligands in Mouse Brain Markedly Extends Sedation and Hypnosis. J Neurosci 43(13): 2338-48, Mar 2023.

Labonte AK, Kafashan MM, Huels ER, Blain-Moraes S, Basner M, Kelz MB, Mashour GA, Avidan MS, Palanca BJ, ReCCognition Study Group: The posterior dominant rhythm: An electroencephalographic biomarker for cognitive recovery after general anaesthesia. Br J Anaesth 130(2): e233-e242, Feb 2023.

Lennertz R, Pryor KO, Raz A, Parker M, Bonhomme V, Schuller P, Schneider G, Moore M, Coburn M, Root JC, Emerson JM, Hohmann AL, Azaria H, Golomb N, Defresne A, Montupil J, Pilge S, Obert DP, van Waart H, Seretny M, Rossaint R, Kowark A, Blair A, Krause B, Proekt A, Kelz M, Sleigh J, Gaskell A, Sanders RD.: Connected consciousness after tracheal intubation in young adults: an international multicentre cohort study. Br J Anaesth 130(2): e217-e224, Feb 2023.

Cichon J, Wasilczuk AZ, Looger LL, Contreras D, Kelz MB, Proekt A.: Ketamine triggers a switch in excitatory neuronal activity across neocortex. Nat Neurosci 26(1): 39-52, Jan 2023.

Kafashan M, Brian Hickman L, Labonte AK, Huels ER, Maybrier H, Guay CS, Subramanian S, Farber NB, Ching S, Hogan RE, Kelz MB, Avidan MS, Mashour GA, Palanca BJA.: Quiescence during burst suppression and postictal generalized EEG suppression are distinct patterns of activity. Clin Neurophysiol 142: 125-32, Oct 2022.

Aggarwal A, Brennan C, Luo J, Chung H, Contreras D, Kelz MB, Proekt A.: Visual evoked feedforward-feedback traveling waves organize neural activity across the cortical hierarchy in mice. Nat Commun 13: 4754, Aug 2022.

Rokos A, Mišić B, Berkun K, Duclos C, Tarnal V, Janke E, Picton P, Golmirzaie G, Basner M, Avidan MS, Kelz MB, Mashour GA, Blain-Moraes S.: Distinct and Dissociable EEG Networks Are Associated With Recovery of Cognitive Function Following Anesthesia-Induced Unconsciousness. Front Hum Neurosci 15: 706693, Sep 2021.

Duclos C, Maschke C, Mahdid Y, Berkun K, Castanheira JDS, Tarnal V, Picton P, Vanini G, Golmirzaie G, Janke E, Avidan MS, Kelz MB, Liuzzi L, Brookes MJ, Mashour GA, Blain-Moraes S.: Differential classification of states of consciousness using envelope- and phase-based functional connectivity. Neuroimage euroimage, Aug 2021.

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Last updated: 06/04/2024
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