Shaon Sengupta, MBBS, MPH, FAAP

faculty photo
Assistant Professor of Pediatrics (Neonatology & Newborn Services)
Department: Pediatrics

Contact information
Children's Hospital of Philadelphia
Abramson Research Center
3615 Curie Blvd
Office: 1102C
Lab 1103
Philadelphia, PA 19104
Office: 267-426-6628
Fax: 215-590-4267
All India Institute of Medical Sciences, India (Medicine and Surgery) , 2006.
Johns Hopkins Bloomberg School of Public Health (Epidemiology and Statistics), 2008.
Permanent link

Description of Research Expertise

Circadian biology, Lung inflammation, Neonatal lung injury, Influenza, Lung regeneration, Lung organoids

Selected Publications

Abdulafiz O. Musa1*, Sydney R. Faber1*, Kaitlyn Forest, Kenneth P. Smith, Shaon Sengupta and Carolina B. López: Identification of distinct genotypes in circulating RSV A strains based on variants on the virus replication-associated genes (under review) 2024.

Joseph Stevens, Erica Culberson, Jeremy Kinder, Alicia Ramiriqui, Jerilyn Gray, Madeline Bonfield, Tzu-Yu Shao, Faris Al Gharabieh, Laura Peterson, Shelby Steinmeyer, William Zacharias, Gloria Pryhuber, Oindrila Paul, Shaon Sengupta, Theresa Alenghat, Sing Sing Way, Hitesh Deshmukh: Microbiota-derived inosine programs protective CD8+ T cell responses against influenza in newborns bioRxiv .04.09.588427; doi: https://doi.org/10.1101/2024.04.09.588427 2024.

Thomas Brooks , Nicholas Lahens , Antonijo Mrčela , Dimitra Sarantopoulou , Soumyashant Nayak , Amruta Naik , Shaon Sengupta , Peter Choi, G.R. Grant: BEERS2: RNA-Seq simulation through high fidelity in silico modeling. Briefings in Bioinformatics 2024.

Naik A, Forrest K, Paul O, Issah Y, Valekunja UK, Tang SY, Reddy AB, Hennessy E, Brooks TS, Chaudhry F, Babu A, Morley M, Zepp JA, Grant GR, FitzGerald GA, Sehgal A, Worthen GS, Frank DB, Morrisey EE, Sengupta S.: Circadian regulation of lung repair and regeneration JCI Insight Page: e164720. doi: 10.1172/jci.insight.164720. August 2023.

Cox SL, O’Siorain JR, He Y, Lordan R, Naik A, Tang SY, Sengupta S, FitzGerald GA, Carroll RG, Curtis AM.: Circadian disruption in lung fibroblasts enhances NF-κB activity to exacerbate neutrophil recruitment. FASEB J 37(2): e22753 Feb 2023.

Christopher M. Cielo, Janet Lioy, Darko Stefanovski, Shaon Sengupta,, Sagori Mukhopadhyay, Mary Anne Cornaglia, Ignacio E. Tapia: Respiratory indices during sleep in healthy infants: a prospective longitudinal study and metanalysis Sleep Medicine 99(1): 49-57, Nov 2022.

S Sengupta, Y Lee, J Q Tao, A Sehgal and S Chatterjee: Circadian Control of Pulmonary Endothelial Signaling occurs via NADPH oxidase 2-NLRP3 pathway. Bioarchives Page: doi: https://doi.org/10.1101/2022.06.05.493624, June 2022 Notes: online pub.

Theken KN, Tang SY, Sengupta S, FitzGerald GA.2021 : The roles of lipids in SARS-CoV-2 viral replication and the host immune response. J Lipid Res. 62(100129): doi: 10.1016/j.jlr.2021.100129, Sep 2021.

Felt SA, Sun Y, Jozwik A, Paras A, Habibi MS, Nickle D, Anderson L, Achouri E, Feemster KA, Cárdenas AM, Turi KN, Chang M, Hartert TV, Sengupta S, Chiu C, López CB: Detection of respiratory syncytial virus defective genomes in nasal secretions is associated with distinct clinical outcomes. Nature Microbiology 6(5): 672-681, May 2021.

Issah Y, Naik A, Tang SY, Forrest K, Brooks TG, Lahens N, Theken KN, Mermigos M, Sehgal A, Worthen GS, FitzGerald GA, Sengupta S: Loss of circadian Protection against Influenza Infection in Adult mice Exposed to Hyperoxia as neonates. eLife (eds.). 2(10): e61241, March 2021.

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Last updated: 04/29/2024
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