Faculty

Kathryn Leigh Wofford

Assistant Professor of Neurosurgery

Department: Neurosurgery

Graduate Group Affiliations

Neuroscience

Contact information

3900 Woodland Avenue
Philadelphia, PA 19104

Email:
kate.wofford@drexel.edu

Education:
BA (Biophysics and Psychology)
Austin College, 2012.
MS (Biomedical Engineering)
Drexel University, 2015.
PhD (Biomedical Engineering)
Drexel University, 2019.

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Description of Research Expertise

Neuroinflammation, traumatic brain injury, immunoengineering, cellular therapies, biomaterials

Selected Publications

Song H, Tomasevich A, Paolini A, Browne KD, Wofford KL, Kelley B, Kantemneni E, Kennedy J, Dolle JP, Cullen DK, Smith DH: Sex differences in the extent of acute axonal pathologies after experimental concussion. Acta Neuropathologica 147(1): 79, May 2024.

Harris JP, Mietus CJ, Browne KD, Keating CE, Brown DP, Wofford KL, Johnson BN, Wolf JA, Smith DH, Cohen AS, Duda JE, Cullen DK: Neuronal somatic plasmalemmal permeability and dendritic beading caused by head rotational traumatic brain injury in pigs – an exploratory study. Frontiers in Cellular Neuroscience 17, July 2023.

Struzyna LA, Browne KD, Burrell JC, Gordián-Vélez WJ, Wofford KL, Kaplan HM, Murthy NS, Chen HI, Duda JE, España RA, Cullen DK: Axonal Tract Reconstruction Using a Tissue-Engineered Nigrostriatal Pathway in a Rat Model of Parkinson's Disease International Journal of Molecular Sciences 23(22): 13985, Nov 2022.

O’Donnell JC, Swanson RL, Wofford KL, Grovola MR, Purvis EM, Petrov D, Cullen DK: Emerging Approaches for Regenerative Rehabilitation following Traumatic Brain Injury. Regenerative Rehabilitation - From Basic Science to the Clinic Sarah M. Greising & Jarrod A Call (eds.). Springer Nature, Page: 409-459, Jun 2022.

Wofford KL, Shultz RB, Burrell JC, Cullen DK: Neuroimmune Interactions and Immunoengineering Strategies in Peripheral Nerve Repai. Progress in Neurobiology 208: 102172, Jan 2022.

Wofford KL, Grovola MR, Adewole DO, Browne KD, Putt ME, O’Donnell JC, Cullen DK: Relationships between injury kinematics, neurological recovery, and pathology following concussion. Brain Communications 3(4): fcab268, Nov 2021.

Grovola MR, Paleologos N, Brown DP, Tran N, Wofford KL, Harris JP, Browne KD, Shewokis PA, Wolf JA, Cullen DK, Duda JE.: Diverse changes in microglia morphology and axonal pathology during the course of 1 year after mild traumatic brain injury in pigs. Brain Pathology 31(5): e12953, Sep 2021.

Huber CM, Patton DA, Wofford KL, Margulies SS, Cullen DK, Arbogast KB: Laboratory assessment of a headband-mounted sensor for measurement of head impact rotational kinematics. Journal of Biomechanical Engineering 143(2): 024502, Feb 2021.

Grovola MR, Paleologos N, Wofford KL, Harris JP, Browne KD, Johnson VE, Duda JE, Wolf JA, Cullen DK.: Mossy cell hypertrophy and synaptic changes in the hilus following mild diffuse traumatic brain injury in pigs. Journal of Neuroinflammation 17(1): 44, Jan 2020.

Wofford KL, Singh BS, Cullen DK, Spiller KL.: Biomaterial-mediated reprogramming of monocytes via microparticle phagocytosis for sustained modulation of macrophage phenotype. Acta Biomaterialia 101: 237-248, Jan 2020.