Yejia Zhang, MD, PhD

faculty photo
Associate Professor of Physical Medicine and Rehabilitation at the Hospital of the University of Pennsylvania
Department: Physical Medicine and Rehabilitation

Contact information
Penn Medicine at Rittenhouse
1800 Lombard Street/1st Floor
Philadelphia, PA 19146
Office: 215-893-2645
Education:
MD (Medicine)
Second Military Medical University, People's Republic of China (PRC), 1989.
PhD (Cell and Molecular Biology)
University of Pennsylvania, 1997.
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Description of Clinical Expertise

Non-operative care of the spine.
Acupuncture to treat chronic pain and promote well being.
Wheel Chair assessment.

Description of Research Expertise

Cell and Molecular Biology
Spine
Intervertebral Disc

Selected Publications

Tian Z, Chen K, Shofer FS, Ciesielski B, Wang H, O'Brien WT, Qin L, Zhang Y.: Gene Expression Changes Precede Elevated Mechanical Sensitivity in the Mouse Intervertebral Disc Injury Model. JOR Spine 8(1), Feb 23 2025.

Jiawei Lu, Zuozhen Tian, Frances S Shofer, Ling Qin, Honghong Sun, Yejia Zhang: Tnfaip8 and Tipe2 Gene Deletion Ameliorates Immediate Proteoglycan Loss and Inflammatory Responses in the Injured Mouse Intervertebral Disc. Am J Phys Med Rehabil 103(10): 918-924, Oct 2024.

Chen K, Tian Z, Wang H, Qin L, Enomoto-Iwamoto M, Zhang Y.: Gene Expression Profiles Perturbed by Injury to the Mouse Intervertebral Disc. Am J Phys Med Rehabil Jul 2024.

Li J, Gui T, Yao L, Guo H, Lin YL, Lu J, Duffy M, Zgonis M, Mauck R, Dyment N, Zhang Y, Scanzello C, Seale P, Qin L.: Synovium and infrapatellar fat pad share common mesenchymal progenitors and undergo coordinated changes in osteoarthritis. J Bone Miner Res 39: 161-176, Mar 2024.

Chen K, Tian Z, Wang H, Enomoto-Iwamoto M, Zhang Y: ADAM8 Inactivation Modulates Cellular Component Assembly Gene Expression in the Mouse Intervertebral Disc. Genes & Diseases 11 2024.

Lu J, Tian Z, Shofer FS, Yao L, Sandroni AZ, Sun H, Qin L, Zhang Y.: Tnfa , Il6 , Cxcl1 , and Adam8 Genes Are the Early Markers After Mouse Tail Intervertebral Disc Injury. Am J Phys Med Rehabil 102: 1063-1069, Dec 2023.

Tian Z, Shofer FS, Fan M, Sandroni AZ, Yao L, Han L, Qin L, Enomoto-Iwamoto M, Zhang Y.: ADAM8 inactivation retards intervertebral disc degeneration in mice. Genes Diseases 11: 101059, Aug 2023.

Lu K, Wang Q, Jiang H, Li J, Yao Z, Huang Y, Chen J, Zhang Y, Xiao G, Hu X, Luo Z, Yang L, Tong L, Chen D.: Upregulation of β-catenin signaling represents a single common pathway leading to the various phenotypes of spinal degeneration and pain. Bone Res 11: 18, Apr 2023.

Tian Z, Shofer FS, Sandroni AZ, Zhao L, Scanzello CR, Zhang Y.: Expression of Human Interleukin 8 in Mice Alters Their Natural Behaviors. J Inflamm Res 15: 2413-2424, Apr 2022.

Song N, Xie P, Shen W, Oh H, Zhang Y, Vitale F, Javanmard M, Allen MG.: A microwell-based impedance sensor on an insertable microneedle for real-time in vivo cytokine detection. Microsyst Nanoeng 7: 96, Nov 2021.

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Last updated: 04/23/2025
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