Faculty

Daniel C Douek, MD, PhD

Adjunct Professor of Pathology and Laboratory Medicine

Department: Pathology and Laboratory Medicine

Graduate Group Affiliations

Immunology

Contact information

40 Convent Drive, Room 3509
Bethesda, MD 20892

Office: 301 594 8484
Fax: 301 480 2565

Email:
ddouek@nih.gov

Education:
BA (Physiological Sciences (Medicine))
University of Oxford, 1987.
M.B.B.S.
University of London, 1990.
M.A. (Physiological Sciences (Medicine))
University of Oxford, 1996.
PhD (Immunology)
University of London, 1996.

Permanent link

> Perelman School of Medicine > Faculty > Details

Selected Publications

Schuetz Alexandra, Deleage Claire, Sereti Irini, Rerknimitr Rungsun, Phanuphak Nittaya, Phuang-Ngern Yuwadee, Estes Jacob D, Sandler Netanya G, Sukhumvittaya Suchada, Marovich Mary, Jongrakthaitae Surat, Akapirat Siriwat, Fletscher James L K, Kroon Eugene, Dewar Robin, Trichavaroj Rapee, Chomchey Nitiya, Douek Daniel C, O Connell Robert J, Ngauy Viseth, Robb Merlin L, Phanuphak Praphan, Michael Nelson L, Excler Jean-Louis, Kim Jerome H, de Souza Mark S, Ananworanich Jintanat: Initiation of ART during Early Acute HIV Infection Preserves Mucosal Th17 Function and Reverses HIV-Related Immune Activation. PLoS pathogens 10(12): e1004543, Dec 2014.

Hill Brenna J, Darrah Patricia A, Ende Zachary, Ambrozak David R, Quinn Kylie M, Darko Sam, Gostick Emma, Wooldridge Linda, van den Berg Hugo A, Venturi Vanessa, Larsen Martin, Davenport Miles P, Seder Robert A, Price David A, Douek Daniel C: Epitope specificity delimits the functional capabilities of vaccine-induced CD8 T cell populations. Journal of immunology (Baltimore, Md. : 1950) 193(11): 5626-36, Dec 2014.

Sandler Netanya G, Zhang Xinyan, Bosch Ronald J, Funderburg Nicholas T, Choi Andrew I, Robinson Janet K, Fine Derek M, Coombs Robert W, Jacobson Jeffrey M, Landay Alan L, Douek Daniel C, Tressler Randall, Read Sarah W, Wilson Cara C, Deeks Steven G, Lederman Michael M, Gandhi Rajesh T: Sevelamer does not decrease lipopolysaccharide or soluble CD14 levels but decreases soluble tissue factor, low-density lipoprotein (LDL) cholesterol, and oxidized LDL cholesterol levels in individuals with untreated HIV infection. The Journal of infectious diseases 210(10): 1549-54, Nov 2014.

Calantone Nina, Wu Fan, Klase Zachary, Deleage Claire, Perkins Molly, Matsuda Kenta, Thompson Elizabeth A, Ortiz Alexandra M, Vinton Carol L, Ourmanov Ilnour, Loré Karin, Douek Daniel C, Estes Jacob D, Hirsch Vanessa M, Brenchley Jason M: Tissue myeloid cells in SIV-infected primates acquire viral DNA through phagocytosis of infected T cells. Immunity 41(3): 493-502, Sep 2014.

Bashford-Rogers Rachael Jm, Palser Anne L, Idris Saad F, Carter Lisa, Epstein Michael, Callard Robin E, Douek Daniel C, Vassiliou George S, Follows George A, Hubank Mike, Kellam Paul: Capturing needles in haystacks: a comparison of B-cell receptor sequencing methods. BMC immunology 15(1): 29, Aug 2014.

Sandler Netanya G, Bosinger Steven E, Estes Jacob D, Zhu Richard T R, Tharp Gregory K, Boritz Eli, Levin Doron, Wijeyesinghe Sathi, Makamdop Krystelle Nganou, del Prete Gregory Q, Hill Brenna J, Timmer J Katherina, Reiss Emma, Yarden Ganit, Darko Samuel, Contijoch Eduardo, Todd John Paul, Silvestri Guido, Nason Martha, Norgren Robert B, Keele Brandon F, Rao Srinivas, Langer Jerome A, Lifson Jeffrey D, Schreiber Gideon, Douek Daniel C: Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression. Nature 511(7511): 601-5, Jul 2014.

Laydon Daniel J, Melamed Anat, Sim Aaron, Gillet Nicolas A, Sim Kathleen, Darko Sam, Kroll J Simon, Douek Daniel C, Price David A, Bangham Charles R M, Asquith Becca: Quantification of HTLV-1 clonality and TCR diversity. PLoS computational biology 10(6): e1003646, Jun 2014.

Mandell Daniel T, Kristoff Jan, Gaufin Thaidra, Gautam Rajeev, Ma Dongzhu, Sandler Netanya, Haret-Richter George, Xu Cuiling, Aamer Hadega, Dufour Jason, Trichel Anita, Douek Daniel C, Keele Brandon F, Apetrei Cristian, Pandrea Ivona: Pathogenic features associated with increased virulence upon Simian immunodeficiency virus cross-species transmission from natural hosts. Journal of virology 88(12): 6778-92, Jun 2014.

Jing Huie, Zhang Qian, Zhang Yu, Hill Brenna J, Dove Christopher G, Gelfand Erwin W, Atkinson T Prescott, Uzel Gulbu, Matthews Helen F, Mustillo Peter J, Lewis David B, Kavadas Fotini D, Hanson I Celine, Kumar Ashish R, Geha Raif S, Douek Daniel C, Holland Steven M, Freeman Alexandra F, Su Helen C: Somatic reversion in dedicator of cytokinesis 8 immunodeficiency modulates disease phenotype. The Journal of allergy and clinical immunology 133(6): 1667-75, Jun 2014.

Gros Alena, Robbins Paul F, Yao Xin, Li Yong F, Turcotte Simon, Tran Eric, Wunderlich John R, Mixon Arnold, Farid Shawn, Dudley Mark E, Hanada Ken-Ichi, Almeida Jorge R, Darko Sam, Douek Daniel C, Yang James C, Rosenberg Steven A: PD-1 identifies the patient-specific CD8⁺ tumor-reactive repertoire infiltrating human tumors. The Journal of clinical investigation 124(5): 2246-59, May 2014.