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Jonathan J Miner, M.D., Ph.D.

Associate Professor of Medicine (Rheumatology)
Associate Professor of Medicine, University of Pennsylvania
Director of the RVCL Research Center, University of Pennsylvania
Department: Medicine
Graduate Group Affiliations

Contact information
522B Johnson Pavilion
3610 Hamilton Walk
Philadelphia, PA 19104
Office: 215-573-4109
Education:
B.S. (Zoology)
BYU, 2002.
B.A. (Russian)
BYU, 2002.
Ph.D. (Biochemistry and Molecular Biology)
University of Oklahoma, 2008.
M.D. (Medicine)
University of Oklahoma, 2010.
Post-Graduate Training
Resident in Internal Medicine, Barnes-Jewish Hospital / Washington University in Saint Louis, 2010-2012.
Fellowship in Rheumatology, Barnes-Jewish Hospital / Washington University in Saint Louis, 2012-2015.
Postdoctoral Fellow, Washington University in St. Louis, 2013-2016.
Certifications
Board Certified in Internal Medicine (ABIM), 2014.
Board Certified in Rheumatology (ABIM), 2015.
Permanent link
 
> Perelman School of Medicine   > Faculty   > Details

Selected Publications

Chauvin SD, Ando S, Holley JA, Sugie A, Zhao FR, Poddar S, Kato R, Miner CA, Nitta Y, Krishnamurthy SR, Saito R, Ning Y, Hatano Y, Kitahara S, Koide S, Stinson WA, Fu J, Surve N, Kumble L, Qian W, Polishchuk O, Andhey PS, Chiang C, Liu G, Colombeau L, Rodriguez R, Manel N, Kakita A, Artyomov MN, Schultz DC, Coates PT, Roberson EDO, Belkaid Y, Greenberg RA, Cherry S, Gack MU, Hardy T, Onodera O, Kato T, Miner JJ.: Inherited C-terminal TREX1 variants disrupt homology-directed repair to cause senescence and DNA damage phenotypes in Drosophila, mice, and humans. Nature Communications 15(1): 4696, Jun 2024.

Miner JJ, Fitzgerald KA.: A path towards personalized medicine for autoinflammatory and related diseases. Nature Reviews Rheumatol 19(3): 182-189, Mar 2023.

Chauvin SD, Stinson WA, Platt DJ, Poddar S, Miner JJ.: Regulation of cGAS and STING signaling during inflammation and infection. Journal of Biological Chemistry 299(7): 104866, July 2023.

Platt DJ, Lawrence D, Qian W, Rodger R, Schriefer L, Miner CA, Menos AM, Kennedy EA, Peterson ST, Stinson WA, Baldridge MT, Miner, JJ: Transferrable protection by gut microbes against STING-associated lung disease. Cell Rep 35(6): 109133, May 2021.

Bennion BG, Croft CA, Ai TL, Qian W, Menos AM, Miner CA, Fremond ML, Doisne JM, Andhey PS, Platt DJ, Bando JK, Wang ER, Luksch H, Molina TJ, Robison EDO, Artyomov MN, Rosen-Wolff A, Colonna M, Rieux-Laucat F, Di Santo JP, Neven B, Miner JJ. : STING gain-of-function disrupts lymph node organogenesis and innate lymphoid cell development in mice. Cell Rep. 31(11): 107771, Jun 2020.

Luksch H, Stinson WA, Platt DJ, Qian W, Kalugotla G, Miner CA, Bennion BG, Gerbaulet A, Rösen-Wolff A, Miner JJ.: STING-associated lung disease in mice relies on T cells but not type I interferon. J Allergy Clin Immunol. 144(1): 154-266, July 2019.

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Last updated: 09/30/2024
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