The RVCL Research Center
Retinal vasculopathy with cerebral leukoencephalopathy (RVCL or RVCL-S) is a rare disease that affects ~50% of the people in families that have the disease. RVCL is caused by mutations in the TREX1 gene.
The University of Pennsylvania (Penn) was our nation's first university and medical school. Today, the University of Pennsylvania and its hospital are leading the way in gene therapy.
The RVCL Research Center at Penn is performing cutting-edge research. Our goal is to develop precision and personalized therapies for RVCL.
We have assembled a team of expert clinicians, researchers, and genetic counselors, who support patients and families with RVCL.