Agenda
Thursday, May 1, 2025
KEYNOTE | PLENARY SESSIONS | CONCURRENT SESSIONS | EXHIBITS
Check-In
Irvine Auditorium
Breakfast, Visit Exhibits and View Posters
Houston Hall
Welcome Remarks
Irvine Auditorium
Carl H. June, MD | Penn Medicine | Symposium Co-Chair
Larry Jameson, MD, PhD | President of the University of Pennsylvania
KEYNOTE PANEL: Closing the Gap: Philanthropy's Role in Equitable CAR-T Access
Moderators:
Carl H. June, MD | Penn Medicine | Symposium Co-Chair
David L. Porter, MD | Penn Medicine | Symposium Co-Chair
Panel:
Valerie A. Arkoosh, MD, MPH | Pennsylvania Secretary of Human Services
Tricia A. Bruning | Penn Medicine Development
Lee Greenberger, PhD | LMG Bio1 Consulting
Stephen Kelly | Children's Hospital of Philadelphia
Tom Whitehead | Emily Whitehead Foundation
PLENARY SESSION 1: Risk and Cost vs. Reward and Benefit for Cell and Gene Therapies
Moderator: Stephan A. Grupp, MD, PhD | Children’s Hospital of Philadelphia | Symposium Co-Chair
Balancing CAR T Promise and Rare Events: Precision, doubt, and assessing risk
Bruce L. Levine, PhD | Penn Medicine | Symposium Co-Chair
Ensuring Access: Policy Challenges and Opportunities in Cell and Gene Therapy
Scott McGoohan, JD | Vertex Pharmaceuticals
Immune Reconstitution after CAR-T: Restoration, Renewal, or Beyond Repair?
Stephen J. Schuster, MD | Penn Medicine
Discussion
Oral Presentation Winner
Gene Delivery and Editing for Better CARs; Enhanced Conversion of T Cells into CAR T Cells by Modulation of the MAPK/ERK Pathway
Elham Adabi, MSc | Paul-Ehrlich-Institut
PLENARY SESSION 2: Leadership in Cell and Gene Therapies: The XX Factor
Moderator: Amanda Finck, PhD | Penn Medicine
Enhancing CAR T Cell Therapy for Pancreatic Cancer
M. Angela Aznar Gomez, PhD | Penn Medicine | The Muriel Joan Drew Hege, MD, Fund Oral Abstract Winner
Leading the Charge For In Vivo Cell Therapy for The Treatment of Autoimmune Disorders
Laura Shawver, PhD | Capstan Therapeutics
Harnessing the Tumor Microenvironment by Genome Editing of T Cells
Chiara Bonini, MD | Vita-Salute San Raffaele University
CAR-T Trailblazers: Grand Adventures and the Power of Women Leadership in Cell and Gene Therapy
Kristen M. Hege, MD | Adaptimmune, EvolveImmune, Kelonia, KSQ, Mersana
Discussion
CONCURRENT SESSION I
There are a total of 6 tracks. Scroll left and right to view all tracks.
Track 1 Pediatric Medical Care - Café 58, Irvine
Track 2 Clinical & Business Operations - Amado Recital Hall, Irvine
Track 3 Nursing Keynotes - Hall of Flags, Ground Fl Houston Hall
Track 4 The Next Disruptions in Cell and Gene Therapy: Hot Topics Lightning Talks from Muriel Joan Drew Hege Fund Scholars - Irvine Auditorium
Track 5 Commercial Partnering & Creating Products for Patients - Class of '49, 2nd Fl Houston Hall
Track 6 Expanding Access While Maintaining Quality: Going Where No CAR T Cell Has Gone Before - Benjamin Franklin, 2nd Fl Houston Hall
Track 1 Pediatric Medical Care - Café 58, Irvine 11:20 am EDT
All speakers from Children’s Hospital of Philadelphia
Moderator:
Stephan Grupp, MD, PhD
Emerging Gene Therapies for Inherited Bone Marrow Failure Syndromes
Julia T. Warren, MD, PhD
Immune Related Adverse Events of CART: What can we learn from pediatric B-ALL?
Caroline Diorio, MD, FRCPC, FAAP
Leveraging Cell Therapies to Treat Autoimmunity in Pediatric Patients
Caitlin Elgarten, MD, MSCE
Discussion
Track 2 Clinical & Business Operations - Amado Recital Hall, Irvine 11:20 am EDT
Moderators:
Mark Duckworth
Children's Hospital of Philadelphia
Robert (Robb) E. Richards, MS, MBA
Penn Medicine
Welcome
Legal Considerations for Cell and Gene Therapies
Denene M. Wambach, Esq
Penn Medicine
Keith Stroup, Esq
Children's Hospital of Philadelphia
Discussion
Data Science in Cell Therapy: From collection to dissemination
Lindsey MacDonald MSN, MBA, RN, OCN
Penn Medicine
Chris Catania, MPH
Penn Medicine
Discussion
Collaborating for Success: A Nurse and Systems Analyst Perspective on Implementing the Epic Cell Therapy Module at CHOP
Roni Devassy, BS
Children's Hospital of Philadelphia
Ryan Burke, BSN, RN, CPHON, BMTCN
Children's Hospital of Philadelphia
Discussion
Track 3 Nursing Keynotes - Hall of Flags, Ground Fl Houston Hall 11:20 am EDT
Moderators:
Heather Difilippo, CRNP
Children's Hospital of Philadelphia
Anna Sparrow, MSN, MPH,RN
Children's Hospital of Philadelphia
Special Welcome Remarks
KEYNOTES
Afami-cel for Synovial Sarcoma: The First Approved TCR Therapy
Daniel Lefler, MD
Penn Medicine
Creating A Space for All: The Pursuit of Belonging
Anna D’Aprile, MPH, CCRP
Children's Hospital of Philadelphia
Hope Heffner-Solimeo, MA, ATR-BC, LPC
Children's Hospital of Philadelphia
Panel Discussion
Session speakers and
Katherine Ebby, MSN, RN, CPHON
Children's Hospital of Philadelphia
Eleni Hindle, BSN, RN, CPHON
Children's Hospital of Philadelphia
Selina Plummersturgis, BSN, RN
Children's Hospital of Philadelphia
Marissa Zangardi, BSN, RN, CPN
Children's Hospital of Philadelphia
Track 4 The Next Disruptions in Cell and Gene Therapy: Hot Topics Lightning Talks from Muriel Joan Drew Hege Fund Scholars - Irvine Auditorium 11:20 am EDT
Moderator:
Kristen M. Hege,MD
Adaptimmune, EvolveImmune, Kelonia, KSQ, Mersana
All speakers are from The Center for Cellular Immunotherapies and The Muriel Joan Drew Hege, MD, Fund awardees
IL-9 Redirects CAR T Cell Fate, Enhancing Efficacy Against Solid Tumors
Sofia Castelli, PhD
Transient Overexpression of IKZF1 Enhances Memory Precursor Phenotype in CAR-T Cells
Sisi Chen, PhD
Modulation of the Gut Microbiota Engages Antigen Cross-Presentation to Enhance Antitumor Effects of CAR T Cells
Francesca Costabile, MSc, PhD
Overcoming Resistance; Deciphering the Glycan and Protein Interactome of Siglec-15: Unraveling its Role in Tumor-Associated Immunosuppression
Nohelly Derosiers, BE
Deciphering the Impact of Immunological Aging in CLL CAR T Cell Therapy
Julia Han Noll, MS
p:Hishing for T Cells: Using ‘Chimeric Antigen-Presenting’ (CAP) T cells to Target and Eliminate Antigen-Specific T cell Populations
Kaitlin A. Read, PhD
Off-the-Shelf CAR-Invariant NKT Cells for Human and Canine Solid Tumors
Antonia Rotolo, MD, PhD
Novel CAR T Cells for Prostate Cancer
Nour Shobaki, PharmD, PhD
Chimeric Autoantigen Receptor T-Cells for Treatment of Antineutrophil Cytoplasmic Antibody Vasculitis
Heather Sosnoski, BS
Discussion
Track 5 Commercial Partnering & Creating Products for Patients - Class of '49, 2nd Fl Houston Hall 11:20 am EDT
Moderator:
John Swartley, MBA, PhD
Penn Medicine
Workshop on Filing, Partnering, and Licensing Cell and Gene Therapy Intellectual Property
Panel
Mark Engleka, PhD
Penn Medicine
Tess Cameron, BA
RA Capital Management
Mir Masud-Elias, JD, MBE
Arnold & Porter
Discussion
Track 6 Expanding Access While Maintaining Quality: Going Where No CAR T Cell Has Gone Before - Benjamin Franklin, 2nd Fl Houston Hall 11:20 am EDT
Moderator:
David L. Porter, MD
Penn Medicine
Expanding Access to Cell Therapies
Steven Devine, MD
National Marrow Donor Program (NMDP) /Be The Match
Discussion
Accelerating Global Access to Point of Care Cell Therapy
Stephan Kadauke, MD, PhD
Children’s Hospital of Philadelphia
Discussion
Quality Program Considerations for Cell Therapies Outside Heme Malignancies
PANEL:
Jenna Fetters MSHS, MLS (ASCP)
Penn Medicine
Victoria Collier, RN, BSN
Children's Hospital of Philadelphia
Becca Pesce-Noga, MS, CSSBB
Penn Medicine
LUNCH BREAK
Lunch | Visit Exhibits | View Posters
Houston Hall
CONCURRENT SESSION II
There are a total of 6 tracks. Scroll left and right to view all tracks.
Track 1 Pediatric Nursing Care - Cafe 58, Irvine
Track 2 Clinical & Business Operations - Amado Recital Hall, Irvine
Track 3 Adult Nursing Care - Hall of Flags, Ground Fl Houston Hall
Track 4 Hot Topics in Cell Therapies - Irvine Auditorium
Track 5 Commercial Partnering & Creating Products for Patients - Class of '49, 2nd Fl Houston Hall
Track 6 Expanding Access While Maintaining Quality: Going Where No CAR T Cell Has Gone Before - Benjamin Franklin, 2nd Fl Houston Hall
Track 1 Pediatric Nursing Care - Cafe 58, Irvine 1:30 pm EDT
All speakers from Children’s Hospital of Philadelphia
Moderators:
Diane Baniewicz MSN, CPNP
Samantha Barone MSN, CPNP-AC, CPHON
Toxicity Management
Immune Effector Cell Associated Hemophagocytic Lymphohistiocytosis Syndrome with CAR 19/22
Colleen Callahan, RN, MSN, CRNP
Mackenzie Stewart, CPNP-AC
Discussion
Improving Patient Partnership in Care
Implementation and Compliance with ICE Scores in AYA Patients Post-CART
Katie A. Smith, DNP, MPH, RN, ACCNS-P, CPN, CHES
Anna Sparrow, MSN, MPH,RN
All Smiles for Clabsi Prevention: Improving Oral Care Completion on the Inpatient Oncology and Blood and Marrow Transplant Units
Catherine Aronowitz, CPN, CPHON
Improving Provider Practice
Teamwork Makes the Marrow Work: Interprofessional Rounds on Inpatient Oncology and Blood and Marrow Transplant Units
Emily Roth, BSN, RN, CPN, CPHON
Sara Gunnoe, MPAS, PA-C
BMT Bootcamp: Education and training best practices for new BMT nurses
Ryan Burke, BSN, RN, CPHON, BMTCN
Megan Atkinson, BS, CHTC
Discussion
Track 2 Clinical & Business Operations - Amado Recital Hall, Irvine 1:30 pm EDT
Moderators:
Mark Duckworth
Children's Hospital of Philadelphia
Robert (Robb) E. Richards, MS, MBA
Penn Medicine
From Coverage Policies to Prior Authorization: Financial Clearance for Cell and Gene Therapies
Panel
Claire White, MSN, RN
Children's Hospital of Philadelphia
Denise Belcher, MBA
Children's Hospital of Philadelphia
Kimberly Sacco, MS
Children's Hospital of Philadelphia
Blueprint for Success: Constructing a Unified Approach for the Future of Cell & Gene Therapy
Kaitlyn Lyons, MBA
Penn Medicine
Discussion
Track 3 Adult Nursing Care - Hall of Flags, Ground Fl Houston Hall 1:30 pm EDT
All speakers from Penn Medicine
Moderators:
Heather Difilippo, CRNP
Patricia Mangan, RN, MSN, CRNP, APRN-BC
CART T Cell Therapy and Bispecifics for Multiple Myeloma
Patricia Mangan, RN, MSN, CRNP, APRN-BC
Overcoming Challenges and Complexities for Cell Therapy Coordinators
Matthew P. Casazza, RN
Natalie K. Stefano, RN
Harnessing EPIC for Cell Therapy Workflows and Data Management
Lindsey MacDonald, MSN, MBA, RN, OCN
Elizabeth A. Weber, RN, BSN
TIL therapy and Inpatient Process Management of Infusion and IL2 toxicities
Lauren B. Hollander, NP
Rachel E. Hartman, PharmD
Discussion
Track 4 Hot Topics in Cell Therapies - Irvine Auditorium 1:30 pm EDT
Moderator:
Elizabeth O. Hexner, MD
Penn Medicine
Lessons from Spatial Biology on CAR HLH/MAS
Andrew J. Rech, MD, PhD
Penn Medicine
Novel CAR Targets for Prostate Cancer and Potential Applications in Renal Cancer
Naomi B. Haas, MD
Penn Medicine
Cytokine Biology behind CAR T Toxicity and Patient Management
David T. Teachey, MD
Children's Hospital of Philadelphia
Discussion
Track 5 Commercial Partnering & Creating Products for Patients - Class of '49, 2nd Fl Houston Hall 1:30 pm EDT
Moderator:
Audrey E. Greenberg, CPA, MBA
Discovery Labs Center for Breakthrough Medicines
Amplifying the Academia and Industry Ecosystem in Cellicon Valley
Panel
R. Carter Caldwell, MBA
Penn Medicine
Jen Gilburg, BS, MS
Pennsylvania Department of Community and Economic Development
John Grady, MPA
Wexford Science & Technology
Discussion
Track 6 Expanding Access While Maintaining Quality: Going Where No CAR T Cell Has Gone Before - Benjamin Franklin, 2nd Fl Houston Hall 1:30 pm EDT
Moderator:
Zev Binder, MD, PhD
Penn Medicine
LATE BREAKERS
Cell Therapies in Brain Cancer
Donald M. O'Rourke, MD
Penn Medicine
Hideho Okada, MD, PhD
University of California San Francisco
Discussion
BREAK
VISIT EXHIBITS | VIEW POSTERS
Houston Hall