Current Students
Degree: PhD
Matriculation Year: 2019
Project Title: CRISPR/Cas9 Genome Targeting for the Implementation of Next Generation of CAR-T Therapies
Advisor(s):
- Daniel Powell
Rotations:
- Marco Ruella
- Daniel Powell
Degree: PhD
Matriculation Year: 2019
Project Title: Neutrophils and chemokines in venous thrombosis
Advisor(s):
- Morty Poncz
Rotations:
- Mark Kahn
- Morty Poncz
- Rodney Camire
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- James Riley
Rotations:
- Lewis Chodosh
- Avery Posey
- Donald O'Rourke
- James Riley
Degree: PhD
Matriculation Year: 2019
Project Title: Application of Targeted Recombination in Active Population to Access Neurons Activated by Social Defeat Stress
Advisor(s):
- Seema Bhatnagar
Rotations:
- Mariella De Biasi
- Seema Bhatnagar
Degree: PhD
Matriculation Year: 2019
Project Title: Reprogramming glioma microenvironment for immunotherapy
Advisor(s):
- Yi Fan
Rotations:
- Yi Fan
- Ellen Pure
Degree: PhD
Matriculation Year: 2019
Project Title: Discovering Regulators of Macrophage Identity in Brain
Advisor(s):
- Frederick (Christian) Bennett
Rotations:
- Frederick (Christian) Bennett
- Shelley Berger
- Elizabeth Heller-Mesznik
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Matt Kayser
Rotations:
- Julie Blendy
- Heath Schmidt
- Matt Kayser
Degree: PhD
Matriculation Year: 2019
Project Title: Transient receptor potential mucolipin 1 (TRPML1) localization patterns and protein binding partners in Mucolipidosis type IV (ML4) mild-to-severe disease mutants
Advisor(s):
- Vera Moiseenkova-Bell
Rotations:
- Vera Moiseenkova-Bell
- Kevin Foskett
Degree: PhD
Matriculation Year: 2019
Project Title: Pro-drug design of DNA-encoded, immune cell engaging, bispecific antibodies to mitigate on-target, off-tumor toxicity in cancer immunotherapy
Advisor(s):
- David Weiner
Rotations:
- Daniel Rader
- David Weiner
Degree: PhD
Matriculation Year: 2019
Advisor(s):
- Kristen Lynch
Rotations:
- Junwei Shi
- James Shorter
- Kristen Lynch
Degree: PhD
Matriculation Year: 2019
Project Title: Development of fratricide resistant CAR-T cells for the treatment of acute myeloid leukemia
Advisor(s):
- Carl June
Degree: PhD
Matriculation Year: 2019
Project Title: Characterizing B7-H3 as an immunotherapeutic target in neuroblastoma
Advisor(s):
- John Maris
Degree: PhD
Matriculation Year: 2018
Project Title: Protecting the retina by removing ferrous iron through chemical chelation or viral gene transfer of the ferroxidase ceruloplasmin
Advisor(s):
- Joshua Duniaef
Rotations:
- Roderic Eckenhoff
- Joshua Duniaef
- Kelly Jordan-Sciutto
Degree: PhD
Matriculation Year: 2017
Project Title: Evaluating the Role of α-Cell Glucokinase in Metabolic Disease
Advisor(s):
- Klaus Kaestner
Rotations:
- Park Cho-Park
- Klaus Kaestner
- Doris Stoffers
Degree: PhD
Matriculation Year: 2015
Project Title: Exploring the role of the gut microbiome in NSAID-induced gastroenteropathy
Advisor(s):
- Garret Fitzgerald
Rotations:
- Caryn Lerman
- Rebecca Simmons
- Tracy Bale
Degree: PhD
Matriculation Year: 2017
Project Title: Extracellular vesicles as biomarkers for monitoring inflammation after traumatic brain injury
Advisor(s):
- David Meaney
Rotations:
- Kelly Jordan-Sciutto
- James Eberwine
- David Meaney
Degree: PhD
Matriculation Year: 2016
Project Title: Epigenetic Reprogramming to Promote Human Antigen-Specific CD8+ T cell Immunity
Advisor(s):
- Beatriz Carreno
Rotations:
- Carl June
- Gerald Linette
- Daniel Powell
Degree: PhD
Matriculation Year: 2017
Project Title: A novel gene therapy strategy for precise fusion oncogene targeting
Advisor(s):
- Saar Gill
Rotations:
- Daniel Powell
- Saar Gill
- Margaret Chou
Degree: PhD
Matriculation Year: 2015
Project Title: Enhancing degradation of amyloid beta in lysosomes of presenilin mutant microglia
Advisor(s):
- Claire Mitchell
Rotations:
- Robert Christopher Pierce
- Benjamin Garcia
- Claire Mitchell
Degree: PhD
Matriculation Year: 2014
Project Title: Insights Into Epigenetic Drug Memories
Advisor(s):
- Elizabeth Heller-Mesznik
Rotations:
- Akiva Cohen
- Elizabeth Heller-Mesznik
- Julie Blendy
Degree: PhD
Matriculation Year: 2015
Project Title: TISSUE-SPECIFIC REGULATION OF IMPRINTED H19/IGF2 CLUSTER
Advisor(s):
- Marisa Bartolomei
Rotations:
- Kelly Jordan-Sciutto
- Klaus Kaestner
- Marisa Bartolomei
Degree: PhD
Matriculation Year: 2015
Project Title: Discovery of a human mitochondrial protein disaggregase
Advisor(s):
- James Shorter
Rotations:
- James Shorter
- Garret Fitzgerald
- Michael Robinson
Degree: PhD
Matriculation Year: 2018
Project Title: Assessing Immune Cell Activation and Function with Novel PET Imaging Probes
Advisor(s):
- Mark Sellmyer
Rotations:
- Dmitry Gabrilovich
- Mark Sellmyer
- Robert Mach
Degree: PhD
Matriculation Year: 2016
Project Title: Dissecting Developmental Patterning and Function of Hydroxymethylcytosine in the Epigenome of Maturing Neurons
Advisor(s):
- Hao Wu
Rotations:
- Julie Blendy
- Zhaolan (Joe) Zhou
- Klaus Kaestner
- Hao Wu
Full descriptionfor EmilyFabyanic
Degree: PhD
Matriculation Year: 2016
Project Title: Elucidating the therapeutic tractability and functional role of SHP2 in ALK-driven high-risk neuroblastoma
Advisor(s):
- Yael Mosse
Rotations:
- Margaret Chou
- Yael Mosse
- Donita Brady
Degree: PhD
Matriculation Year: 2017
Project Title: Effects of PERK haplotype on APP pathology in Alzheimer's disease
Advisor(s):
- Kelly Jordan-Sciutto
Rotations:
- Kelly Jordan-Sciutto
- David Lynch
- Benjamin Garcia
Degree: PhD
Matriculation Year: 2015
Project Title: Mitochondrial lipid peroxidation products as markers and drivers of rotenone toxicity"
Advisor(s):
- Ian Blair
Rotations:
- Ian Blair
- Aalim Weljie
- Marilyn Howarth
- Michael Pack
Degree: PhD
Matriculation Year: 2016
Project Title: Development and Validation of a pH-Sensitive Probe for Cerenkov Imaging of the Tumor Microenvironment"
Advisor(s):
- Edward Delikatny
Rotations:
- Andrew Tsourkas
- Donita Brady
- Edward Delikatny
Degree: PhD
Matriculation Year: 2017
Project Title: Elucidation of the optical and therapeutic properties of near-infrared fluorescent inhibitors of choline kinase α for the treatment of lung cancers
Advisor(s):
- Edward Delikatny
Rotations:
- Kelly Jordan-Sciutto
- Yair Argon
- Edward Delikatny
Degree: PhD
Matriculation Year: 2016
Project Title: Investigating the role of ADAMTS proteases and versican in the molecular pathogenesis of cerebral cavernous malformations
Advisor(s):
- Mark Kahn
Rotations:
- Mark Kahn
- Margaret Chou
- Nancy Speck
Degree: PhD
Matriculation Year: 2017
Project Title: Development of a Small Molecule Sensor for Cell-Cell Interactions
Advisor(s):
- Mark Sellmyer
Rotations:
- Robert Mach
- Saar Gill
- Mark Sellmyer
Degree: PhD
Matriculation Year: 2016
Project Title: The role of acute frataxin deficiency on mitochondrial bioenergetic impairments in Friedreich Ataxia
Advisor(s):
- David Lynch
Degree: PhD
Matriculation Year: 2016
Project Title: Credentialing Delta-like 3 as an oncoprotein and immunotherapeutic target in neuroblastoma
Advisor(s):
- John Maris
Rotations:
- James Shorter
- Klaus Kaestner
- John Maris
Degree: PhD
Matriculation Year: 2017
Project Title: Characterizing ALCAM as an oncoprotein an immunotherapeutic target in neuroblastoma
Advisor(s):
- John Maris
Rotations:
- Donita Brady
- Margaret Chou
- John Maris
Degree: PhD
Matriculation Year: 2016
Project Title: Deciphering Chronometabolic Dysfunction in Drosophila Short Sleep Models
Advisor(s):
- Aalim Weljie
Rotations:
- Margaret Chou
- David Lynch
- Aalim Weljie
Degree: PhD
Matriculation Year: 2017
Project Title: Neuronal and homeostatic regulation of sleep by the preoptic area and tuberomammillary nucleus
Advisor(s):
- Shinjae Chung
Rotations:
- Mariella De Biasi
- Elizabeth Heller-Mesznik
- Seema Bhatnagar
- Shinjae Chung
Degree: PhD
Matriculation Year: 2014
Project Title: Development and validation of a novel mouse model to evaluate the cell-type specific contribution of E2F1 to age-associated neurodegeneration
Advisor(s):
- Kelly Jordan-Sciutto
Rotations:
- Steve Thomas
- Kelly Jordan-Sciutto
- Paul Axelsen
Degree: PhD
Matriculation Year: 2014
Project Title: APC Regulation of GSK-3 Activity
Advisor(s):
- Peter Klein
Rotations:
- Patrick Viatour
- Peter Klein
- Xianxin Hua
Degree: PhD
Matriculation Year: 2015
Project Title: Near-Infrared Fluorescent Choline Kinase α Inhibitor for Intraoperative Lung Cancer Imaging
Advisor(s):
- Edward Delikatny
Rotations:
- James Shorter
- Ian Blair
- Edward Delikatny
Degree: PhD
Matriculation Year: 2018
Project Title: Evaluating pharmacokinetic profile and T-cell-mediated cytotoxicity of DNA-encoded bispecific antibody in a mouse GBM model
Advisor(s):
- David Weiner
Rotations:
- Margaret Chou
- Michael Farwell
- David Weiner
Degree: PhD
Matriculation Year: 2014
Project Title: Effects of Sweet Flavorants in E-cigarettes on Nicotine Reward in Adolescent Mice
Advisor(s):
- Mariella De Biasi
Rotations:
- Julie Blendy
- Mariella De Biasi
- Tracy Bale
Degree: PhD
Matriculation Year: 2018
Project Title: The Androgenic Impact of AKR1C3 and the 11-Oxygenated Androgens on PCOS
Advisor(s):
- Trevor Penning
Rotations:
- Margaret Chou
- Trevor Penning
- Garret Fitzgerald
Degree: PhD
Matriculation Year: 2017
Project Title: Identification of Post-Translational Modification State-Based Liver Injury Biomarker
Advisor(s):
- Ian Blair
Rotations:
- Aalim Weljie
- Ian Blair
- Robert Levy
Degree: PhD
Matriculation Year: 2018
Project Title: The role of the nuclear receptor co-repressor RIP140 in the control of muscle fitness
Advisor(s):
- Daniel Kelly
Rotations:
- Kirk Wangensteen
- Yael Mosse
- Daniel Kelly
- Doris Stoffers
Degree: PhD
Matriculation Year: 2016
Project Title: From Therapeutic to Companion Diagnostic: Characterizing a Brain Penetrable PARP inhibitor in Glioblastoma
Advisor(s):
- Robert Mach
Rotations:
- Robert Mach
- Vladimir Muzykantov
- Eric Brown
Degree: PhD
Matriculation Year: 2015
Project Title: Investigating molecular and genetic influencers of alcohol-related behaviors in mice
Advisor(s):
- Mariella De Biasi
Rotations:
- Mariella De Biasi
- Robert Christopher Pierce
- Elizabeth Heller-Mesznik
Degree: PhD
Matriculation Year: 2017
Project Title: Elucidating the Epigenetic Mechanisms Involved in the Origins of Adult Metabolic Outcomes Following in utero DEHP Exposure
Advisor(s):
- Marisa Bartolomei
Rotations:
- Trevor Penning
- Rebecca Simmons
- Marisa Bartolomei
Degree: PhD
Matriculation Year: 2017
Project Title: Molecular synchronization of protein homeostasis by 4EBP1-PI31
Advisor(s):
- Park Cho-Park
Rotations:
- Jeffrey Field
- Benjamin Garcia
- Park Cho-Park
Degree: PhD
Matriculation Year: 2016
Project Title: Investigating the role of ∆133p53α in improving persistence and cytotoxicity of chimeric antigen receptor T cells
Advisor(s):
- Carl June
Rotations:
- Mitchell Lazar
- Carl June
- Roger Greenberg
Degree: PhD
Matriculation Year: 2015
Project Title: Mechanisms of White Matter Loss due to HIV infection and Antiretroviral Therapies
Advisor(s):
- Kelly Jordan-Sciutto
- Judith Grinspan
Rotations:
- Julie Blendy
- Kelly Jordan-Sciutto
- Roderic Eckenhoff
Degree: PhD
Matriculation Year: 2017
Project Title: TCRVb CAR T cell therapy for precision targeting of T cell malignant clones
Advisor(s):
- Daniel Powell
Rotations:
- Julie Blendy
- Tzipora (Karin) Eisinger
- Michael Farwell
- Daniel Powell
Degree: PhD
Matriculation Year: 2018
Project Title: Modulation of the NLRP3 inflammasome by cannabinoids in hiPSC models of HAND
Advisor(s):
- Kelly Jordan-Sciutto
Rotations:
- Kelly Jordan-Sciutto
- Frances Jensen
- James Shorter
Degree: PhD
Matriculation Year: 2017
Project Title: Roles of G Protein-Coupled Receptor Kinase-2 (GRK2) on MRGPRX2/Mrgprb2 and FcεRI-mediated responses in mast cells
Advisor(s):
- Hydar Ali
Degree: PhD
Matriculation Year: 2017
Project Title: Ontogeny and molecular determinants of tumor migratory dendritic cells
Advisor(s):
- Malay Haldar
Degree: PhD
Matriculation Year: 2018
Project Title: The Role of ROCK2 in Resistance of Hepatocellular Carcinoma to Sorafenib Treatment
Advisor(s):
- Kirk Wangensteen
Degree: PhD
Matriculation Year: 2015
Project Title: The consequences of progerin expression on mechanosensation and arterial stiffening in Hutchinson-Gilford Progeria Syndrome
Advisor(s):
- Richard Assoian
Degree: PhD
Matriculation Year: 2018
Project Title: Investigating the Role of β-Cell Senescence in Type 2 Diabetes Pathology
Advisor(s):
- Klaus Kaestner
Degree: PhD
Matriculation Year: 2017
Project Title: Elucidating the role of the medial habenula in the co-abuse of nicotine and opioids
Advisor(s):
- Mariella De Biasi
Degree: PhD
Matriculation Year: 2018
Project Title: Neuronal and homeostatic regulation of sleep and wake by corticotropin-releasing hormone neurons in the paraventricular nucleus of the hypothalamus
Advisor(s):
- Shinjae Chung
Degree: PhD
Matriculation Year: 2017
Project Title: Elucidating the pathomechanism of germline histone H3.3 mutations on neurodevelopment
Advisor(s):
- Benjamin Garcia
Degree: PhD
Matriculation Year: 2016
Project Title: Elucidating the role of Anaplastic Lymphoma Kinase signaling in Neuroblastoma
Advisor(s):
- Yael Mosse
- Ravi Radhakrishnan
Degree: PhD
Matriculation Year: 2018
Project Title: Exploring Mechanisms of MEK Inhibitor Resistance in Malignant Peripheral Nerve Sheath Tumors by Targeting the Hippo Pathway
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