Arterial Hemodynamics and Cardiac Imaging Quantification Core Laboratory

Our Arterial Hemodynamics and Cardiac Imaging Quantification Core Laboratory offers advanced, noninvasive analysis of cardiac and arterial function for human research, with a focus on early-phase clinical trials in hypertension and heart failure.

Using state-of-the-art imaging techniques, we specialize in noninvasive assessments of cardiac and arterial structure and function using a combination of deep phenotyping quantification and imaging modalities (e.g., echocardiography and cardiac MRI), including the assessment of arterial stiffness and pulsatile hemodynamics.

Our lab has served as the Core Lab for numerous population studies (MESA, PREVENCION), industry trials (Barostim HOPE4HF, NeoHF), and NIH-funded projects (HeartShare, KNOCK OUT HFpEF, BLOCK HFpEF, and more).

The foundation to any successful study is the production of high quality data. Our Core Lab provides a comprehensive Quality Control system from data submission to data transmission. All data that is transmitted to the Core Lab is checked for completeness and quality by our highly trained and knowledgeable staff. Feedback to the site is provided based on the study specific requirements and guidelines. This ensures that study sites adhere to their stated goals and receive constructive assessments on acquired data to assist in surpassing these standards. Furthermore, once all data has been checked for quality upon transmission to the Core Lab, all quantified and processed data that is transmitted from the Core Lab is thoroughly inspected by our modality-specific experts and Dr. Chirinos. This additional level of scrutiny, prior to data transmission, ensures that our collaborators receive quantified data of the best possible quality.

These Services include: