Participate in Research

Quit Smoking Studies

The University of Pennsylvania's Tobacco Use Research Center is conducting a research study examining the effects of personalized smoking cessation medication treatment (in addition to smoking cessation counseling) to help people with HIV quit smoking.

Participants will:

  • Attend up to 4 in person sessions (2 definite) and complete 7 phone sessions
  • Take a study medication (either varenicline or nicotine patch) for up to 12 weeks
  • Provide biological samples and complete physiological assessments
  • Complete brief psychiatric assessments and a routine medical history.

If you are a daily cigarette smoker, over the age of 18, and have a confirmed diagnosis of HIV, you may be eligible to participate in this study. Participants are compensated for their time and effort.

For more information and to see if you are eligible, please call 215-746-2715 or visit our survey page. It may take a few days to return your call due to the volume of interest. Thank you!

The University of Pennsylvania’s Tobacco use Research Center is conducting a research study to investigate if using e-cigarettes and oral nicotine pouches help smokers to transition away from combustible cigarette smoking and reduce their exposure to harmful chemicals.

Participants will:

  • Attend up to 9 in-person sessions.
  • Provide breath samples.
  • Provide urine samples.
  • Answer questionnaires.
  • Be randomly assigned to either e-cigarettes or oral nicotine pouches.
  • Use an e-cigarette or oral nicotine pouch in one of our well-ventilated smoking rooms.
  • Return their used cigarette filters and e-cigarette pods or nicotine pouches to the Center.

If you are a daily cigarette smoker who is at least 21 years old and is interested in quitting smoking by switching to a less harmful form of nicotine delivery, you may be eligible to participate in this study.

For more information and to see if you are eligible, please call 215-746-8420 or visit our survey page. It may take a few days to return your call due to the volume of interest. Thank you!

The University of Pennsylvania’s Tobacco Use Research Center is conducting a research study examining the effect of flavor on the ability to switch from combustible cigarettes to electronic cigarettes among smokers who have been unable to quit with traditional approaches.

Participants will:

  • Attend up to 9 in-person sessions.
  • Provide breath samples.
  • Provide urine samples.
  • Answer questionnaires.
  • Be randomly assigned to tobacco-, menthol-, or fruit-flavored e-cigarettes.
  • Use an e-cigarette in one of our well-ventilated smoking rooms.
  • Return their used cigarette filters and e-cigarette pods to the Center.

If you are a daily cigarette smoker who is at least 21 years old and is interested in quitting smoking by switching to an electronic cigarette, you may be eligible to participate in this study.

For more information and to see if you are eligible, please call 215-746-8420 or visit our survey page. It may take a few days to return your call due to the volume of interest. Thank you!

Non-Quit Studies

The Strasser team at the Center for Interdisciplinary Research on Nicotine Addiction (CIRNA) is recruiting smokers of at least 5 filtered, non-menthol cigarettes a day between the ages of 21-65 for a research study examining the effects of different levels of nicotine  

Eligible participants will complete 9 sessions over 5 weeks and receive investigational low nicotine cigarettes for 30 days at no cost. Most sessions will take about 1-2 hours to complete. The study will begin with a remote Intake visit (completed by video call). During 5 in-person sessions at our Center, participants will provide breath samples, answer questionnaires, and smoke a cigarette in our Center’s well-ventilated smoking rooms. Participants will also be asked to provide a urine sample at 2 of the in-person sessions. During 3 remote sessions, participants will complete a brief check in with staff and smoke a cigarette at home. Over the course of the study, participants will be asked to collect their used cigarette filters in bags provided by the Center.  

Sessions will be scheduled Monday through Friday during business hours.  Participants will be compensated for their time and effort for each session they complete. This is NOT a quit smoking program. Our research center will follow strict COVID-19 precautions and 4 of the 9 sessions will be completed remotely (i.e. by video call). 

For more information and to see if you are Eligible call (215) 746-5786 or visit our Cigarette Packaging of Low Nicotine Cigarettes Study page.