Perelman School of Medicine at the University of Pennsylvania

The Center for Interdisciplinary Research on Nicotine Addiction

CIRNA

Participate in Research

Please click on the research study for more information!

Smoking Cessation Optimization for Individuals living with HIV

Quit-Smoking Study

The University of Pennsylvania's Tobacco Use Research Center is conducting a research study examining the effects of personalized smoking cessation medication treatment (in addition to smoking cessation counseling) to help people with HIV quit smoking.

Participants will:

  • Attend up to 4 in person sessions (2 definite) and complete 7 phone sessions
  • Take a study medication (either varenicline or nicotine patch) for up to 12 weeks
  • Provide biological samples and complete physiological assessments
  • Complete brief psychiatric assessments and a routine medical history.

If you are a daily cigarette smoker, over the age of 18, and have a confirmed diagnosis of HIV, you may be eligible to participate in this study. 

For more information and to see if you are eligible, please call 215-746-2715 or visit http://www.philaquits.com/. It may take a few days to return your call due to the volume of interest. Thank you!

 

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Tobacco Product Advertising Study

Non-Quit Study

The University of Pennsylvania's Tobacco Research Center is recruiting young adult smokers and non-smokers who are between the ages of 21-29 for a research study evaluating reactions to tobacco product advertising.

Eligible participants will complete one virtual session and on in-person visit, each lasting no more than one hour. Sessions will be scheduled Monday through Friday during business hours (8am-6pm) only. Participants will be compensated $50 for their time and effort at the end of the in-person visit.

This is not a quit smoking program.

To find out more about the study and see if you may be eligible, go to https://redcap.link/yla_prescreen

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Neural Basis of Eating Behavior in Abstinent Smokers

Non-Quit Study

The purpose of this research study is to better understand why people gain weight when they quit smoking by examining food intake and changes in brain activity in smokers when they are smoking as usual compared to when they have been deprived of cigarettes (i.e., have not smoked for 4 days) as compared to a non-smoker control group.

The Study includes up to 10 in-person visits. You will be asked to complete two 4-day study periods (days 1-4 & 29-32): one while smoking as usual and the other while not smoking (even a single puff) for the entire period. During these periods, you will be contacted to complete a total of 6 24-hour dietary recalls (3 per study period). You will be asked to come to our Center on 4 consecutive days of each period for a monitoring visit; on the 4th visit of each period you will be asked to complete an MRI scan session. These scans will take place in a standard, closed MRI scanner and your brain activity will be measured using a technique called functional magnetic resonance imaging (fMRI). Between each of the 4-day study periods (days 5-28) you will not be required to attend any in-person visits and will be asked to smoke as usual; this is called a “washout period”. You will be compensated for time and travel.

Phone Number: 215-746-7144

Website: www.phillyquit.com

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CENIC Marketplace Study

Non-Quit Study

The Strasser team at the Center for Interdisciplinary Research on Nicotine Addiction (CIRNA) is recruiting smokers, 21 and older for a research study examining the effects of different levels of nicotine on tobacco use patterns and overall health. 

Eligible participants will complete 14 sessions over 20 weeks and receive investigational cigarettes and access to a study marketplace for 12 weeks at no cost. Most sessions will take about 2 hours to complete. All study visits will start with a telehealth portion which will be completed by video call and will include, questionnaires, breath sample collection and blood pressure assessment. Participants will be asked to complete a curbside visit following each telehealth visits in order to receive study products, return biological samples and sign study paperwork. Subjects will be asked to complete a follow up appointment 4 weeks after stopping study product. 

Sessions will be scheduled Monday through Friday during business hours.  Participants will be compensated for their time and effort for each session they complete. This is NOT a quit smoking program. Our research center will follow strict COVID-19 precautions by running telehealth visits followed by  (i.e. by video call). 

For more information and to see if you are Eligible call (215) 746-8421.

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Cigarette Packaging of Low Nicotine Cigarettes

Non-Quit Study

The Strasser team at the Center for Interdisciplinary Research on Nicotine Addiction (CIRNA) is recruiting smokers of at least 5 filtered, non-menthol cigarettes a day between the ages of 21-65 for a research study examining the effects of different levels of nicotine  

Eligible participants will complete 9 sessions over 5 weeks and receive investigational low nicotine cigarettes for 30 days at no cost. Most sessions will take about 1-2 hours to complete. The study will begin with a remote Intake visit (completed by video call). During 5 in-person sessions at our Center, participants will provide breath samples, answer questionnaires, and smoke a cigarette in our Center’s well-ventilated smoking rooms. Participants will also be asked to provide a urine sample at 2 of the in-person sessions. During 3 remote sessions, participants will complete a brief check in with staff and smoke a cigarette at home. Over the course of the study, participants will be asked to collect their used cigarette filters in bags provided by the Center.  

Sessions will be scheduled Monday through Friday during business hours.  Participants will be compensated for their time and effort for each session they complete. This is NOT a quit smoking program. Our research center will follow strict COVID-19 precautions and 4 of the 9 sessions will be completed remotely (i.e. by video call). 

For more information and to see if you are Eligible call (215) 746-5786 or visit https://clinicalresearch.itmat.upenn.edu/clinicaltrial/6356/medical-research-effects-cigarette-package-color/?qd=2258119

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Cigar Packaging Study

Non-Quit Study

The Strasser team at the Center for Interdisciplinary Research on Nicotine Addiction (CIRNA) is recruiting cigarillo smokers between the ages of 21-65 for a research study examining the effects of smoking cigarillos supplied by our research team.  

Eligible participants will complete 6 sessions over 3 weeks and receive study-provided cigarillos for 15 days at no cost. Most sessions will take about 1.5 hours to complete. During 2 in-person sessions at our Center, participants will answer questionnaires, provide a small urine sample and smoke a cigarillo in one of our Center’s well-ventilated smoking rooms. During 4 remote sessions (completed by phone or video call), participants will answer questionnaires and smoke a cigarillo at home. We will also ask participants to collect their used cigarillo “tips/ends” in bags provided by the Center.  

Sessions will be scheduled Monday through Friday during business hours. Participants will be compensated for their time and effort for each session they complete. This is NOT a quit smoking program. Our research center will follow strict COVID-19 precautions and 4 of the 6 sessions will be completed remotely (i.e. by video call). 

For more information and to see if you are Eligible call (215) 898-9933 or visit https://clinicalresearch.itmat.upenn.edu/D5J7/

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Impact of Nicotine Messaging on Beliefs and Behavior

Non-Quit Study

The Strasser team at the Center for Interdisciplinary Research on Nicotine Addiction (CIRNA) is recruiting smokers of at least 5 filtered, non-menthol cigarettes a day ages 21+ for a research study exploring the impact of nicotine messaging on beliefs and behavior while using investigational cigarettes with either normal nicotine levels or reduced nicotine levels.  

Eligible participants will complete 6 in-person sessions over 6 weeks, view messages on a computer while having their eye movements recorded and receive investigational cigarettes for 28 days at no cost. Most sessions will take about 1.5-2 hours to complete. During sessions at our center, participants will provide breath samples, answer questionnaires, and smoke cigarettes in our Center’s well-ventilated smoking rooms. Participants will also be asked to provide a small urine sample at 2 of the sessions. Over the course of the study, participants will be asked to collect their used cigarette filters in bags provided by the Center. 

Sessions will be scheduled Monday through Friday during business hours.  Participants will be compensated for their time and effort for each session they complete. This is NOT a quit smoking program. Our research center will follow strict COVID-19 precautions.  

For more information and to see if you are eligible, call 215-746-7876 or visit https://clinicalresearch.itmat.upenn.edu/clinicaltrial/7086/impact-of-nicotine-messaging-on-beliefs-and-behavior/

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IQOS Study

Non-Quit Study

The University of Pennsylvania's Tobacco Use Research Center is conducting a research study examining the effects of IQOS use on cigarette smoking behavior. IQOS is a commercially available Heat-Not-Burn tobacco product, which is an electronic device that heats tobacco at a constant temperature rather than burning it. Participants will attend up to 8 in-person sessions, provide breath samples, answer questionnaires, use an IQOS device in one of our well-ventilated smoking labs, and return their used cigarette filters and IQOS HeatSticks to the Center.

If you are a daily cigarette smoker between the ages of 18 and 65, you may be eligible to participate in this study. For more information and to see if you are eligible, please call 215-746-2100 or visit iqosandsmokingbehavior.com.  

It may take a few days to return your call due to the volume of interest. Thank you!

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FLAV Study

Non-Quit Study

The University of Pennsylvania's Tobacco Use Research Center is recruiting young adults between the ages of 18 and 24 for a research study examining flavoring in cigarillos. Eligible participants will complete 3 in-person sessions lasting 1-2.5 hours and receive study-provided flavored and non-flavored cigarillos to smoke in-center at no cost. Eligible persons will also be asked to abstain from tobacco use for 10 hours prior to 2 visits. Sessions will be scheduled Monday through Friday at approximately 1:00PM. Participants will be compensated for their time and travel for each session they complete.


This is NOT a quit smoking program.

For more information and to see if you are eligible, please call 215-746-2100 or visit www.cigarilloflavoring.com. It may take a few days to return your call due to the volume of interest. Thank you!

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