Peter Carman
Graduate student

B.S. 2017 Rutgers University - School of Environmental and Biological Sciences- Biotechnology, Biochemistry

E-mail: pcarman at pennmedicine . upenn . edu
Phone: (215) 573-0983

Publications

Carman PJ, Barrie KR, Rebowski G, Dominguez R (2023) Structures of the free and capped ends of the actin filament. Science.
DOI: 10.1126/science.adg6812
Highlighted in Penn Today and in Faculty Opinions

Carman PJ, Rebowski G, Dominguez R, Alqassim SS (2023) Single particle cryo-EM analysis of Rickettsia conorii Sca2 reveals a formin-like core.
J Struct Biol. DOI: 10.1016/j.jsb.2023.107960

Zapater CIM, Carman PJ, Soffar DB, Windner SE, Dominguez R, Baylies MK (2023) Drosophila Tropomodulin is required for multiple actin-dependent processes within developing myofibers. Development. DOI: 10.1242/dev.201194

Ceron RH, Carman PJ, Rebowski G, Boczkowska M, Heuckeroth RO, Dominguez R (2022) A solution to the long-standing problem of actin expression and purification. PNAS 119(41). DOI: 10.1073/pnas.2209150119

Carman PJ, Dominguez R (2022) Novel Protein Production Method Combining Native Expression in Human Cells with an Intein-based Affinity Purification and Self-cleavable Tag. Bio-Protocol 12(6): e4363. DOI: 10.21769/BioProtoc.4363

Carman PJ, Barrie KR, Dominguez R (2021) Novel human cell expression method reveals the role and prevalence of posttranslational modification in non-muscle tropomyosins bioRxiv, DOI: https://doi.org/10.1101/2021.04.05.438513

Cason SE, Carman PJ , Van Duyne C, Goldsmith J, Dominguez R, Holzbaur ELF (2021) Sequential dynein effectors regulate axonal autophagosome motility in a maturation-dependent pathway J Cell Biol, 220(7):e202010179, DOI: https://doi.org/10.1083/jcb.202010179

Baker RW, Reimer JM, Carman PJ, Turegun B, Arakawa T, Dominguez R, Leschziner AE (2020) Structural insights into assembly and function of the RSC chromatin remodeling complex. Nat Struct Mol Biol DOI: 10.1038/s41594-020-00528-8

Kumari R, Jiu Y, Carman PJ, Tojkander S, Kogan K, Varjosalo M, Gunning PW, Dominguez R, Lappalainen P (2020) Tropomodulins Control the Balance between Protrusive and Contractile Structures by Stabilizing Actin-Tropomyosin Filaments. Current Biology 30: 1–12. doi.org/10.1016/j.cub.2019.12.049

Tariq A, Lin J, Jackrel ME, Hesketh CD, Carman PJ, Mack KL, Weitzman R, Gambogi C, Hernandez Murillo OA, Sweeny EA, Gurpinar E, Yokom AL, Gates SN, Yee K, Sudesh S, Stillman J, Rizo AN, Southworth DR, Shorter J (2019) Mining Disaggregase Sequence Space to Safely Counter TDP-43, FUS, and α-Synuclein Proteotoxicity. Cell Reports 28: 2080–2095. doi.org/10.1016/j.celrep.2019.07.069

Carman PJ and Dominguez R (2018) BAR domain proteins – a linkage between cellular membranes, signaling pathways and the actin cytoskeleton. Biophys Rev 10:1587–1604. DOI: 10.1007/s12551-018-0467-7