Personnel
Principal Investigator
Garret A. FitzGerald, MD, FRS
garret@upenn.edu
215-898-1185
Dr. FitzGerald's research has been characterized by an integrative approach to elucidating the mechanisms of drug action, drawing on work in cells, model organisms and humans. His work contributed substantially to the development of low-dose aspirin for cardioprotection. FitzGerald's lab was the first to predict and then mechanistically explain the cardiovascular harzard from NSAIDs. He has also discovered many products of lipid peroxidation and established their utility as indices of oxidant stress in vivo. His laboratory was the first to discover a molecular clock in the cardiovascular system and has studied the importance of peripheral clocks in the regulation of cardiovascular and metabolic function.
Faculty
Tilo Grosser, MD
Research Associate Professor
tilo@pennmedicine.upenn.edu
215-573-7600
Research Expertise: Non-steroidal anti-inflammatory drugs (NSAIDs)
George Paschos, PhD
Research Assistant Professor
gpaschos@pennmedicine.upenn.edu
215-898-8360
Research Expertise: Circadian regulation of metabolism
Emanuela Ricciotti, PharmD, PhD
Research Assistant Professor
emanuela@pennmedicine.upenn.edu
215-898-9391
Research Expertise: Genomic, proteomic and metabolomics analysis of inflammatory pathways in vascular cells.
Shaon Sengupta, MBBS, MPH
Attending Neonatolgist, CHOP & Instructor, Penn
SenguptaS@email.chop.edu
Research Interests: Circadian underpinnings of lung inflammation
Carsten C. Skarke, MD
Research Assistant Professor
cskarke@pennmedicine.upenn.edu
215-662-7186
Research Expertise: Human Clock Biology and Human Phenomics
Staff
LaVenia Banas
Clinical Research Nurse
banas@pennmedicine.upenn.edu
Susanne Fries
Sr. Research Investigator
fries@upenn.edu
Damien Lekkas
Research Specialist A
dlekkas@sas.upenn.edu
Sarah Teegarden
Associate Director / Lab Manager
sarahtee@pennmedicine.upenn.edu
Research Interests: Circadian rhythms, fitness, and metabolism
Weili Yan
Research Specialist C
weiliyan@pennmedicine.upenn.edu
Research Interests: Small animal surgical models
Postdocs
Sean Anderson
Postdoc Researcher
seanth@pennmedicine.upenn.edu
Soumita Ghosh
Postdoc Researcher
soumita@pennmedicine.upenn.edu
Research Interests: Interindividual variability of NSAID pharmacokinetics and pharmacodynamics
Abbie Glascock
Postdoc Researcher
Abigail.Glascock@pennmedicine.upenn.edu
Research Interests: Gut microbiome and drug metabolism
Liz Hennessy
Postdoc Researcher
ehenn@pennmedicine.upenn.edu
Research Interests: Long non-coding RNAs as regulators of cardiovascular disease and inflammation
Luda Mazaleuskaya
Research Associate
mazali@pennmedicine.upenn.edu
Research Interests: Lipidomics, pharmacology of NSAIDs, cyclooxygenase and mPGES-1 biology
Hu Meng
Postdoc Researcher
menghu@pennmedicine.upenn.edu
Research Interests: Proteomics in circadian biology, systems biology of prostaglandins, liquid chromatography - mass spectrometry
Soon Yew Tang
Research Associate
tangsoon@pennmedicine.upenn.edu
Research Interests: The role of prostaglandins in cardiometabolic function
Katie Theken
Research Associate
ktheken@pennmedicine.upenn.edu
Research Interests: Interindividual variability in NSAID response, dose-dependent effects of COX-2 deletion
Students
Kayla Barekat
PhD Student - Pharmacology
kbarekat@pennmedicine.upenn.edu
Research Interests: NSAID-microbiome interactions and gastroenteropathy
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