Publications
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Circadian regulation of lung repair and regeneration.
JCI insight. 2024 Mar 8;9(5); Authors: Naik A, Forrest KM, Paul O, Issah Y, Valekunja UK, Tang SY, Reddy AB, Hennessy EJ, Brooks TG, Chaudhry F, Babu A, Morley M, Zepp JA, Grant GR, FitzGerald GA, Sehgal A, Worthen GS, Frank DB, Morrisey EE, Sengupta S -
Prostanoids in Cardiac and Vascular Remodeling.
Arteriosclerosis, thrombosis, and vascular biology. 2024 Mar;44(3):558-583 Epub 2024 Jan 25; Authors: Ricciotti E, Haines PG, Chai W, FitzGerald GA -
Designer high-density lipoprotein particles enhance endothelial barrier function and suppress inflammation.
Science signaling. 2024 Feb 20;17(824):eadg9256; Authors: Lin YC, Swendeman S, Moreira IS, Ghosh A, Kuo A, Rosário-Ferreira N, Guo S, Culbertson A, Levesque MV, Cartier A, Seno T, Schmaier A, Galvani S, Inoue A, Parikh SM, FitzGerald GA, Zurakowski D, Liao M, Flaumenhaft R, Gümüş ZH, Hla T -
Challenges and best practices in omics benchmarking.
Nature reviews. Genetics. 2024 Jan 12; Authors: Brooks TG, Lahens NF, Mrčela A, Grant GR -
Prognostic utility of rhythmic components in 24-h ambulatory blood pressure monitoring for the risk stratification of chronic kidney disease patients with cardiovascular co-morbidity.
Journal of human hypertension. 2024 Jan 11; Authors: El Jamal N, Brooks TG, Cohen J, Townsend RR, Sosa GR, Shah V, Chronic Renal Insufficiency Cohort Study (CRIC) Consortium, Nelson RG, Drawz PE, Rao P, Bhat Z, Chang A, Yang W, FitzGerald GA, Skarke C -
COX Postulates: Remember the Fibroblast.
Arteriosclerosis, thrombosis, and vascular biology. 2024 Jan;44(1):287-289 Epub 2023 Nov 16; Authors: FitzGerald GA -
PGF2α signaling drives fibrotic remodeling and fibroblast population dynamics in mice.
JCI insight. 2023 Dec 22;8(24); Authors: Rodriguez LR, Tang SY, Roque Barboza W, Murthy A, Tomer Y, Cai TQ, Iyer S, Chavez K, Das US, Ghosh S, Cooper CH, Dimopoulos TT, Babu A, Connelly C, FitzGerald GA, Beers MF -
Endothelial lipid droplets suppress eNOS to link high fat consumption to blood pressure elevation.
The Journal of clinical investigation. 2023 Dec 15;133(24); Authors: Kim B, Zhao W, Tang SY, Levin MG, Ibrahim A, Yang Y, Roberts E, Lai L, Li J, Assoian RK, FitzGerald GA, Arany Z -
Meta-analysis of Diurnal Transcriptomics in Mouse Liver Reveals Low Repeatability of Rhythm Analyses.
Journal of biological rhythms. 2023 Dec;38(6):556-570 Epub 2023 Jun 29; Authors: Brooks TG, Manjrekar A, Mrcˇela A, Grant GR -
Failure to apply standard limit-of-detection or limit-of-quantitation criteria to specialized pro-resolving mediator analysis incorrectly characterizes their presence in biological samples.
Nature communications. 2023 Nov 9;14(1):7172; Authors: O'Donnell VB, Schebb NH, Milne GL, Murphy MP, Thomas CP, Steinhilber D, Gelhaus SL, Kühn H, Gelb MH, Jakobsson PJ, Blair IA, Murphy RC, Freeman BA, Brash AR, FitzGerald GA -
Deep phenotyping of the lipidomic response in COVID-19 and non-COVID-19 sepsis.
Clinical and translational medicine. 2023 Nov;13(11):e1440; Authors: Meng H, Sengupta A, Ricciotti E, Mrčela A, Mathew D, Mazaleuskaya LL, Ghosh S, Brooks TG, Turner AP, Schanoski AS, Lahens NF, Tan AW, Woolfork A, Grant G, Susztak K, Letizia AG, Sealfon SC, Wherry EJ, Laudanski K, Weljie AM, Meyer NJ, FitzGerald GA -
Diurnal rhythms of wrist temperature are associated with future disease risk in the UK Biobank.
Nature communications. 2023 Aug 24;14(1):5172; Authors: Brooks TG, Lahens NF, Grant GR, Sheline YI, FitzGerald GA, Skarke C -
Circadian regulation of lung repair and regeneration.
JCI insight. 2023 Aug 22;8(16); Authors: Naik A, Forrest KM, Paul O, Issah Y, Valekunja UK, Tang SY, Reddy AB, Hennessy EJ, Brooks TG, Chaudhry F, Babu A, Morley M, Zepp JA, Grant GR, FitzGerald GA, Sehgal A, Worthen GS, Frank DB, Morrisey EE, Sengupta S -
Modulation of the Immune Response to Severe Acute Respiratory Syndrome Coronavirus 2 Vaccination by Nonsteroidal Anti-Inflammatory Drugs.
The Journal of pharmacology and experimental therapeutics. 2023 Aug;386(2):198-204 Epub 2023 Apr 27; Authors: Skarke C, Lordan R, Barekat K, Naik A, Mathew D, Ohtani T, Greenplate AR, Grant GR, Lahens NF, Gouma S, Troisi E, Sengupta A, Weljie AM, Meng W, Luning Prak ET, Lundgreen K, Bates P, Meng H, FitzGerald GA -
Disruption of the Clock Component Bmal1 in Mice Promotes Cancer Metastasis through the PAI-1-TGF-β-myoCAF-Dependent Mechanism.
Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2023 Aug;10(24):e2301505 Epub 2023 Jun 17; Authors: Wu J, Jing X, Du Q, Sun X, Holgersson K, Gao J, He X, Hosaka K, Zhao C, Tao W, FitzGerald GA, Yang Y, Jensen LD, Cao Y -
Disruption of Prostaglandin F(2α) Receptor Signaling Attenuates Fibrotic Remodeling and Alters Fibroblast Population Dynamics in A Preclinical Murine Model of Idiopathic Pulmonary Fibrosis.
bioRxiv : the preprint server for biology. 2023 Jun 7; Authors: Rodriguez LR, Tang SY, Barboza WR, Murthy A, Tomer Y, Cai TQ, Iyer S, Chavez K, Das US, Ghosh S, Dimopoulos T, Babu A, Connelly C, FitzGerald GA, Beers MF -
Deep Phenotyping of the Lipidomic Response in COVID and non-COVID Sepsis.
bioRxiv : the preprint server for biology. 2023 Jun 2; Authors: Meng H, Sengupta A, Ricciotti E, Mrčela A, Mathew D, Mazaleuskaya LL, Ghosh S, Brooks TG, Turner AP, Schanoski AS, Lahens NF, Tan AW, Woolfork A, Grant G, Susztak K, Letizia AG, Sealfon SC, Wherry EJ, Laudanski K, Weljie AM, Meyer NB, FitzGerald GA -
Sexual dimorphism in the response to chronic circadian misalignment on a high-fat diet.
Science translational medicine. 2023 May 17;15(696):eabo2022; Authors: Anderson ST, Meng H, Brooks TG, Tang SY, Lordan R, Sengupta A, Nayak S, Mřela A, Sarantopoulou D, Lahens NF, Weljie A, Grant GR, Bushman FD, FitzGerald GA -
Prognostic utility of rhythmic components in 24-hour ambulatory blood pressure monitoring for the risk stratification of chronic kidney disease patients with cardiovascular co-morbidity.
medRxiv : the preprint server for health sciences. 2023 May 5; Authors: Jamal NE, Brooks TG, Cohen J, Townsend RR, de Sosa GR, Shah V, Nelson RG, Drawz PE, Rao P, Bhat Z, Chang A, Yang W, FitzGerald GA, Skarke C, CRIC Study Investigators -
BEERS2: RNA-Seq simulation through high fidelity in silico modeling.
bioRxiv : the preprint server for biology. 2023 Apr 24; Authors: Brooks TG, Lahens NF, Mrčela A, Sarantopoulou D, Nayak S, Naik A, Sengupta S, Choi PS, Grant GR -
Nonsteroidal anti-inflammatory drugs as a targeted therapy for bone marrow failure in Ghosal hematodiaphyseal dysplasia.
Blood. 2023 Mar 30;141(13):1553-1559; Authors: Brown TJ, Barrett N, Meng H, Ricciotti E, McDonnell C, Dancis A, Qualtieri J, FitzGerald GA, Cotter M, Babushok DV -
Editorial: Streaming inflammation: From damage to healing and resilience-Volume II.
Frontiers in pharmacology. 2023;14:1185593 Epub 2023 Mar 24; Authors: Devchand PR, Schadt EE, FitzGerald GA -
RNA splicing analysis using heterogeneous and large RNA-seq datasets.
Nature communications. 2023 Mar 3;14(1):1230; Authors: Vaquero-Garcia J, Aicher JK, Jewell S, Gazzara MR, Radens CM, Jha A, Norton SS, Lahens NF, Grant GR, Barash Y -
The genetic and evolutionary basis of gene expression variation in East Africans.
Genome biology. 2023 Feb 24;24(1):35; Authors: Kelly DE, Ramdas S, Ma R, Rawlings-Goss RA, Grant GR, Ranciaro A, Hirbo JB, Beggs W, Yeager M, Chanock S, Nyambo TB, Omar SA, Woldemeskel D, Belay G, Li H, Brown CD, Tishkoff SA -
Circadian disruption in lung fibroblasts enhances NF-κB activity to exacerbate neutrophil recruitment.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2023 Feb;37(2):e22753; Authors: Cox SL, O'Siorain JR, He Y, Lordan R, Naik A, Tang SY, Sengupta S, FitzGerald GA, Carroll RG, Curtis AM -
A microbiome-dependent gut-brain pathway regulates motivation for exercise.
Nature. 2022 Dec;612(7941):739-747 Epub 2022 Dec 14; Authors: Dohnalová L, Lundgren P, Carty JRE, Goldstein N, Wenski SL, Nanudorn P, Thiengmag S, Huang KP, Litichevskiy L, Descamps HC, Chellappa K, Glassman A, Kessler S, Kim J, Cox TO, Dmitrieva-Posocco O, Wong AC, Allman EL, Ghosh S, Sharma N, Sengupta K, Cornes B, Dean N, Churchill GA, Khurana TS, Sellmyer MA, FitzGerald GA, Patterson AD, Baur JA, Alhadeff AL, Helfrich EJN, Levy M, Betley JN, Thaiss CA -
Tempo: an unsupervised Bayesian algorithm for circadian phase inference in single-cell transcriptomics.
Nature communications. 2022 Nov 2;13(1):6580; Authors: Auerbach BJ, FitzGerald GA, Li M -
Drugs for the prevention and treatment of COVID-19 and its complications: An update on what we learned in the past 2 years.
Frontiers in pharmacology. 2022;13:987816 Epub 2022 Oct 10; Authors: Remuzzi G, Schiaffino S, Santoro MG, FitzGerald GA, Melino G, Patrono C -
Acetaminophen, Nonsteroidal Anti-Inflammatory Drugs, and Hypertension.
Hypertension (Dallas, Tex. : 1979). 2022 Sep;79(9):1922-1926 Epub 2022 Jul 7; Authors: Spence JD, Grosser T, FitzGerald GA -
Editorial: Streaming Inflammation: From Damage to Healing and Resilience.
Frontiers in pharmacology. 2022;13:969453 Epub 2022 Jul 12; Authors: Devchand PR, Schadt EE, FitzGerald GA