Ivan P. Maillard, MD/PhD
Adjunct Professor of Medicine (Hematology-Oncology)
Department: Medicine
Division: Hematology-Oncology
Graduate Group Affiliations
Contact Information
Memorial Sloan Kettering Cancer Center
1275 York Avenue
New York, NY 10065
Office: 215-746-2929
Email: imaillar@pennmedicine.upenn.edu
I3H Keywords
- Cancer Immunology and Immunotherapy
- Immune System Development and Function in Host Homeostasis
Education
-
BA
Gymnase de Chamblandes, 1986 -
MD (Medicine )
University of Lausanne and Zurich, 1993 -
MD-PhD (Medicine)
Swiss Academy of Medical Sciences, 1997
Post-Graduate Training
-
Resident in Internal Medicine (interim)
University of Lausanne Medical Center, 1994 - 1994 -
Resident in Internal Medicine
University of Lausanne Medical Center , 1997 - 2001 -
Fellow in Hematology-Oncology
Hospital of the University of Pennsylvania , 2001 - 2004 -
Post-Doctoral Fellow
University of Pennsylvania School of Medicine , 2002 - 2007
Certifications
- American Board of Internal Medicine , 2015
- American Board of Internal Medicine - Hematology , 2016
- ECFMG Certification , 2000
- Swiss Board of Internal Medicine , 2001
- Swiss Boards of Hematology , 2015
Description of Clinical Expertise
Hematological malignancies
Description of Research Expertise
My laboratory investigates the regulation of normal and malignant hematopoiesis, bone marrow transplantation and T cell alloimmunity. A central focus of our studies is the role of Notch signaling in T cell development, differentiation and function. Using mouse models of bone marrow transplantation, we discovered essential functions for Notch receptors and ligands in graft-versus-host disease with a high fundamental and translational impact. We are also interested to understand the role of fibroblastic reticular cells as a source of Notch ligands and other signals in secondary lymphoid organs, with a focus on their emerging roles in immune regulation as well as in immunological and hematological disorders.
Description of ITMAT Expertise
Hematopoietic stem cells, T and B cell immunology, lymphomas, bone marrow transplantation, Notch signaling