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Gregory P Bisson, MD/MSCE

Associate Professor of Medicine (Infectious Diseases)

  • Senior Scholar, Department of Biostatistics and Epidemiology, Perelman School of Medicine

Department: Medicine
Division: Infectious Diseases


Graduate Group Affiliations


Contact Information

04-307, 3600 Civic Center Boulevard
Center for Clinical Epidemiology and Biostatistics
University of Pennsylvania
Philadelphia, PA 19104-6021
Office: 215-573-5811
Fax: 215-573-5315
Email: bisson@pennmedicine.upenn.edu


I3H Keywords

  • Allergy, Asthma, and Other Inflammatory Diseases

Education

  • BA (Japanese)
    University of Wisconsin-Madison, 1992
  • MD
    University of Minnesota School of Medicine, 1997
  • MSCE (Epidemiology)
    Perelman School of Medicine, University of Pennsylvania, 2006

Post-Graduate Training

  • Intern
    Department of Medicine, School of Medicine, University of Pennsylvania, 1997 - 1998
  • Resident
    Department of Medicine, School of Medicine, University of Pennsylvania, 1998 - 2000
  • Fellow, Division of Infectious Diseases
    Department of Medicine, School of Medicine, University of Pennsylvania, 2000 - 2003
  • Fellow, Pharmacoepidemiology, Division of Epidemiology
    Department of Biostatistics and Epidemiology, School of Medicine, University of Pennsylvania, 2001 - 2003

Certifications

  • American Board of Internal Medicine, Internal Medicine, 2000
  • American Board of Internal Medicine, Infectious Diseases, 2015

Description of Research Expertise

My research is dedicated to improving treatment outcomes of patients with HIV and tuberculosis (TB) and other AIDS-associated opportunistic infections. Current research projects are evaluating the relationship between very early virologic and immunologic response to antiretroviral therapy and clinical outcomes in adults with HIV/TB. Many patients with advanced HIV die soon after antiretroviral therapy initiation, and our research group focuses on trying to understand the pathophysiologic and social mechanisms underlying these early deaths. In addition, we are pursuing translational projects evaluating novel host-directed therapies for treatment of drug resistant TB.

Description of ITMAT Expertise

HIV infection, tuberculosis, cryptococcal meningitis, host-directed therapy, HIV treatment monitoring in resource-limited settings, drug resistance

Selected Publications

  • Rina Liang, James C.M. Brust, Caitlin Reed, Vincent Escuyer, Derek T. Armstrong, Nicole Parrish, Patrick Valois, Marie-Claire Rowlinson, Atanaska Marinova-Petkova, Gregory P. Bisson, Sarah M. Labuda, Angel Colon-Semidey, Connie A. Haley, David Ashkin, Charles A. Peloquin, Alfred Lardizabal, Amee Patrawalla, Alice Cuenca, Michelle K. Haas, Richard Brostrom, Chima Mbakwem, Marcos C. Schechter, Susan M. Ray, Jason Cummins, Barbara Cahill, Katherine Arn, Lisa L. Chen, John W. Wilson, Neela D. Goswami : Relapse and Emergent Resistance With Novel Short-Course Regimens for Multidrug-Resistant Tuberculosis Open Forum Infectious Diseases 13(1) Jan 2026 Notes: DOI: 10.1093/ofid/ofaf786
  • Liang R, Brust JCM, Reed C, Escuyer V, Armstrong DT, Parrish N, Valois P, Rowlinson MC, Marinova-Petkova A, Bisson GP, Labuda SM, Colon-Semidey A, Haley CA, Ashkin D, Peloquin CA, Lardizabal A, Patrawalla A, Cuenca A, Haas MK, Brostrom R, Mbakwem C, Schechter MC, Ray SM, Cummins J, Cahill B, Arn K, Chen LL, Wilson JW, Goswami ND. : Relapse and Emergent Resistance With Novel Short-Course Regimens for Multidrug-Resistant Tuberculosis, United States, 2022-2024 Open Forum Infect Dis 13 : ofaf786, Jan 2026
  • M. Marll, S. El Sammak, F. Willis, A. Queiroz, A. Rajaratnam, N. Mofokeng, L. Mngomezulu, P. Maenetje, G. Bisson, S. Auld, : Patterns of pulmonary impairment before and after tuberculosis treatment Union Conference 2025 Nov 2025
  • M. Marll, A. Rajaratnam, F. Willis, A. Queiroz, T. Ngwanto, P. Maenetje, L. Jane Choene, R. Ramaite Malemela, R. Nkanyane, G. Bisson, S. Auld, : Trajectories of lung function in people with and without HIV during and after pulmonary tuberculosis treatment Union Conference 2025 Nov 2025
  • Mochankana, Kagiso; Bah, Muhammed; Bisson, Greg; Celso, Khosa; Htet, Kyaw; Meghji, Jamilah; Navuluri, Neelima; Rachow, Andrea; Masekela, Refiloe : Post-Tuberculosis Lung Disease Evaluation in Paediatric National Guidelines: Scoping Review of High-Burden Countries International Journal of Tuberculosis and Lung Disease Open Sep 2025
  • Muhammed S. Bah, Kyaw Ko Ko Htet, Gregory P. Bisson, Celso Khosa, Refiloe Masekela, Jamilah Meghji, Kagiso Mochankana, Andrea Rachow, Neelima Navuluri : Assessment of Comorbidities, Risk Factors, and Post Tuberculosis Lung Disease in National Tuberculosis Guidelines: A Scoping Review PLOS Global Public Health 5(7) : e0004935, Jul 2025 Notes: DOI: 10.1371/journal.pgph.0004935
  • Alvaro A. Ordonez, Mboyo-di-tamba Willy Vangu, Anisha Rajaratnam, Nomsa Mofokeng, Lungile Gabuza, Pholo Maenetje, Mariane Le Fur, Sydney B. Montesi, Peter Caravan, Sara C. Auld, Gregory P. Bisson : Collagen-targeted PET/CT imaging of tuberculosis patients European Respiratory Journal 66(1) : 2500195, Jul 2025 Notes: doi: 10.1183/13993003.00195-2025
  • Mugoma S, Wiebe D, Larson PS, Li Y, Bisson GP : The impact of COVID-19 and public health measures on homicide and suicide trends in Botswana using an interrupted time series analysis Inj Epidemiol 12(1) : 42, Jul 2025 Notes: DOI: 10.1186/s40621-025-00592-y
  • Auld SC, Bisson GP : Post-tuberculosis Sequelae and the Burden of "Long TB": Continuing TB Care after Treatment Completion American Journal of Respiratory and Critical Care Medicine 211(6) : 912-913, Jun 2025 Notes: doi: 10.1164/rccm.202502-0442ED
  • Meghji J, Auld SC, Bisson GP, Khosa C, Masekela R, Navuluri N, Rachow A : Post-tuberculosis lung disease: Towards prevention, diagnosis and care Lancet Respir Med. 13(5) : 460-472, May 2025 Notes: DOI: 10.1016/S2213-2600(24)00429-6