Taku Kambayashi, MD/PhD
Professor of Pathology and Laboratory Medicine

- Attending Physician, Hospital of the University of Pennsylvania (8 weeks/year)
- Director, Institute for Immunology Clinical Fellows Training Program, PSOM
- Program Advisor, Medical Scientist Training Program, PSOM
- Member, Pathology Residency Steering Committee, HUP
- Associate Vice Chair of Research, Department of Pathology, PSOM
Department: Pathology and Laboratory Medicine
Graduate Group Affiliations
Contact Information
288 JMB, 3620 Hamilton Walk
Philadelphia, PA 19104
Office: 215-746-7610
Fax: 215-573-9261
Email: taku.kambayashi@uphs.upenn.edu
I3H Keywords
- Allergy, Asthma, and Other Inflammatory Diseases
- Autoimmunity
- Transplantation Immunity
Publications
Links
Education
-
B.S. (Biomedical Engineering)
Johns Hopkins University, Baltimore, MD, 1993 -
Ph.D. (Immunology)
Emory University, Atlanta, GA, 2002 -
M.D. (Medicine)
Emory University, Atlanta, GA, 2004
Post-Graduate Training
-
Resident in Pathology and Laboratory Medicine
Hospital of the University of Pennsylvania, Philadelphia, PA, 2004 - 2007 -
Transfusion Medicine Fellow
Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, 2007 - 2008 -
Post-doctoral Fellow in Pathology and Laboratory Medicine
University of Pennsylvania School of Medicine, Philadelphia, PA, 2005 - 2008
Certifications
- Clinical Pathology - American Board of Pathology, 2008
- Transfusion Medicine - American Board of Pathology, 2008
Description of Clinical Expertise
Transfusion Medicine
Description of Research Expertise
https://kambayashilab.com/
Research interests:
Regulation of T cell responses; Signal transduction; Regulation of skin barrier function; Skin commensals; Transgenerational epigenetic inheritance
Specific Projects:
1) TSLP-mediated regulation of systemic lipid metabolism by T cells.
2) Regulation of skin barrier function and sebum secretion by Vitamin D3.
3) Regulation of systemic lipid metabolism by skin and skin commensals.
4) Mouse models of Idiopathic Multicentric Castleman Disease (iMCD)
5) Regulation of the epigenome of gametes (sperm and egg) by T cells and microbes. The impact of parental T cells and microbes on progeny phenotypes.
Lab personnel:
Wei Du, MD, PhD, Postdoctoral Fellow
Bruk Goshu, PhD Student
Tetsuya Ikawa, MD, PhD, Postdoctoral Fellow
Dorottya Laczko, MD, PhD, Postdoctoral Fellow
Mariko Okumura, Research Specialist
Lillian Sun, MD/PhD Student
Saba Tegegne, MD/PhD Student
Yuichi Yokoyama, MD, PhD, Postdoctoral Fellow
Simon Zhou, PhD Student
Description of ITMAT Expertise
Cell signaling in immune cells and the impact of these pathways on inflammatory diseases.