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Edward Cantu, MD/MSCE

Professor of Surgery at the Hospital of the University of Pennsylvania

  • Attending Surgeon, Hospital of the University of Pennsylvania, Philadelphia, PA
  • Director of Ex Vivo Lung Perfusion , Hospital of the University of Pennsylvania, Philadelphia, PA
  • Director of Lung Transplant Research, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
  • Director ILD Service Line, Hospital of the University of Pennsylvania, Philadelphia, PA
  • Leadership Advisory Board, Penn Center for Transplant Science and Innovation

Department: Surgery


Contact Information

Hospital of the University of Pennsylvania
Department of Surgery
Division of Cardiovascular Surgery
One Convention Avenue, Pavilion 2 City
Philadelphia, PA 19104-4283
Office: 215-615-6582
Fax: 215-349-5798
Email: edward.cantu@uphs.upenn.edu


I3H Keywords

  • Transplantation Immunity

Publications

Pubmed Link


Links


Education

  • BA
    Harvard University, Cambridge, MA, 1994
  • MD
    Columbia University College of Physicians and Surgeons, New York, NY, 2000
  • MS (Clinical Epidemiology )
    Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 2015

Post-Graduate Training

  • Intern in General and Thoracic Surgery
    Duke University Medical Center, Durham, NC, 2000 - 2001
  • Junior Assistant Resident in General and Thoracic Surgery
    Duke University Medical Center, Durham, NC, 2001 - 2002
  • Research Fellow in Thoracic Transplantation
    Duke University Medical Center, Durham, NC, 2002 - 2004
  • Senior Assistant Resident in General and Thoracic Surgery
    Duke University Medical Center, Durham, NC, 2004 - 2006
  • Chief Resident in General and Thoracic Surgery
    Duke University Medical Center, Durham, NC, 2006 - 2007
  • Cardiothoracic Surgery Resident
    Duke University Medical Center, Durham, NC, 2007 - 2010
  • Summer Research Fellow
    Mayo Clinic, Rochester, MN, 1995 - 1995
  • Research Fellow
    American Heart Association/ Columbia University, New York, NY, 1996 - 1997
  • NIH NRSA Fellow
    Duke University Medical Center, Durham, NC, 2002 - 2004

Certifications

  • American Board of Thoracic Surgery, 2010
  • Advanced Trauma and Life Support Instructor, American College of Surgeons (through 2008), 2004

Description of Clinical Expertise

Lung Transplantation

Description of Research Expertise

Lung donor risk predicion
Donor optimization
Ex Vivo Lung Perfusion
Prediction of lung PGD
Mechanisms of PGD
Therapeutics for PGD

Description of ITMAT Expertise

Lung donor risk predicion
Donor optimization
Ex Vivo Lung Perfusion
Prediction of lung PGD
Mechanisms of PGD
Therapeutics for PGD

Selected Publications

  • Niethamer TK, Planer JD, Morley MP, Babu A, Zhao G, Basil MC, Cantu E, Frank DB, Diamond JM, Nottingham AN, Li S, Sharma A, Hallquist H, Levin LI, Zhou S, Vaughan AE, Morrisey EE. : Longitudinal single-cell profiles of lung regeneration after viral infection reveal persistent injury-associated cell states Cell Stem Cell 32 : 302-321, Feb 2025
  • Kukreja J, Campo-Canaveral de la Cruz JL, Van Raemdonck D, Cantu E, Date H, D'Ovidio F, Hartwig M, Klapper JA, Kelly RF, Lindstedt S, Rosso L, Schaheen L, Smith M, Whitson B, Saddoughi SA, Cypel M. : The 2024 American Association for Thoracic Surgery expert consensus document: Current standards in donor lung procurement and preservation J Thorac Cardiovasc Surg 2025
  • Wang JY, Michki SN, Sitaraman S, Banaschewski BJ, Jamal R, Gokey JJ, Lin SM, Katzen JB, Basil MC, Cantu E, Kropski JA, Zepp JA, Frank DB, Young LR. : Dysregulated alveolar epithelial cell progenitor function and identity in Hermansky-Pudlak syndrome JCI Insight 10 : e183483, Dec 2024
  • Jones DL, Morley MP, Li X, Ying Y, Zhao G, Schaefer SE, Rodriguez LR, Cardenas-Diaz FL, Li S, Zhou S, Chembazhi UV, Kim M, Shen C, Nottingham A, Lin SM, Cantu E, Diamond JM, Basil MC, Vaughan AE, Morrisey EE. : An injury-induced mesenchymal-epithelial cell niche coordinates regenerative responses in the lung Science 386 : eado5561, Dec 2024
  • Evans JF, Ledwell OA, Tang Y, Rue R, Mukhitov AR, Diesler R, Lin SM, Kanth SV, Basil MC, Cantu E, Henske EP, Krymskaya VP. : The Bi-Steric Inhibitor RMC-5552 Reduces mTORC1 Signaling and Growth in Lymphangioleiomyomatosis Am J Respir Cell Mol Biol Nov 2024
  • Rojas-Quintero J, Ochsner SA, Lee HS, Cong C, Cohen AW, Colborg AS, Tsoyi K, Basil MC, Cantu E, Rosas IO, McKenna NJ, Estépar RS, Barjaktarevic I, Wilson AA, Polverino F. : Skewed adaptive immune responses are involved in AATD emphysema Eur Respir J 65 : 2400839, Oct 2024
  • Zamora ME, Essien EO, Bhamidipati K, Murthy A, Liu J, Kim H, Patel MN, Nong J, Wang Z, Espy C, Chaudhry FN, Ferguson LT, Tiwari S, Hood ED, Marcos-Contreras OA, Omo-Lamai S, Shuvaeva T, Arguiri E, Wu J, Rauova L, Poncz M, Basil MC, Cantu E, Planer JD, Spiller K, Zepp J, Muzykantov VR, Myerson JW, Brenner JS. : Marginated Neutrophils in the Lungs Effectively Compete for Nanoparticles Targeted to the Endothelium, Serving as a Part of the Reticuloendothelial System ACS Nano 18 : 22275-22297, Aug 2024
  • Moneme AN, Hunt M, Friskey J, McCurry M, Jin D, Diamond JM, Anderson MR, S Clausen E, Saleh A, Raevsky A, Christie JD, Schaubel D, Hsu J, Localio AR, Gallop R, Cantu E. : Evaluating US Multiple Listing Practices in Lung Transplantation: Unveiling Hidden Disparities Chest Aug 2024
  • Ismail MK, Araki T, Gefter WB, Suzuki Y, Raevsky A, Saleh A, Yusuf S, Marquis A, Alcudia A, Duncan I, Schaubel DE, Cantu E, Rizi R. : Artificial intelligence-driven automated lung sizing from chest radiographs Am J Transplant Aug 2024
  • Koyama T, Zhao Z, Balmes JR, Calfee CS, Matthay MA, Reilly JP, Porteous MK, Diamond JM, Christie JD, Cantu E, Ware LB; Lung Transplant Outcomes Group. : Long-term air pollution exposure and the risk of primary graft dysfunction after lung transplantation J Heart Lung Transplant Jul 2024