Hamideh Parhiz, Pharm.D., Ph.D.

Selected Publications

• Shuvaev VV, Tam YK, Lee BW, Myerson JW, Herbst A, Kiseleva RY, Glassman PM, Parhiz H, Alameh MG, Pardi N, Muramatsu H, Shuvaeva TI, Arguiri E, Marcos-Contreras OA, Hood ED, Brysgel TV, Nong J, Papp TE, Eaton DM, Riley R, Palanki R, Musunuru K, Brenner JS, Mitchell MJ, Ferrari VA, Mui BL, Semple SC, Weppler SA, Atluri P, Margulies KB, Weissman D, Muzykantov VR. : Systemic delivery of biotherapeutic RNA to the myocardium transiently modulates cardiac contractility in vivo Proc Natl Acad Sci U S A 122 : e2409266122, Jul 2025
• Papp TE, Zeng J, Shahnawaz H, Akyianu A, Breda L, Yadegari A, Steward J, Shi R, Li Q, Mui BL, Tam YK, Weissman D, Rivella S, Shuvaev V, Muzykantov VR, Parhiz H. : CD47 peptide-cloaked lipid nanoparticles promote cell-specific mRNA delivery Mol Ther 33 : 3195-3208, Jul 2025
• Nakamichi S, von Muhlinen N, Yamada L, Melamed JR, Papp TE, Parhiz H, Weissman D, Horikawa I, Harris CC. : SRSF3 knockdown-induced cellular senescence as a possible therapeutic strategy for non-small cell lung cancer bioRxiv May 2025
• Reyes-Esteves S, Majumder A, Marzolini N, Zamora M, Wang Y, Espy C, Papp TE, Akyianu A, Nong J, Messe L, Omo-Lamai S, Parhiz H, Myerson J, Marcos-Contreras O, Brenner J. : Targeted lipid nanoparticles containing IL-10 mRNA improve outcomes in experimental intracerebral hemorrhage Res Sq Apr 2025
• Yashaswini CN, Cogliati B, Qin T, To T, Williamson T, Papp TE, Li K, Rasul R, Chen L, Lightstone A, Aghajanian H, Parhiz H, Wang S, Rurik JG, Epstein JA, Friedman SL. : In vivo anti-FAP CAR T therapy reduces fibrosis and restores liver homeostasis in metabolic dysfunction-associated steatohepatitis bioRxiv Feb 2025
• Kimura K, Aicher A, Niemeyer E, Areesawangkit P, Tilsed C, Fong KP, Papp TE, Albelda SM, Parhiz H, Predina JD. : In Situ Tumor Vaccination Using Lipid Nanoparticles to Deliver Interferon-β mRNA Cargo Vaccines (Basel) 13 : 178, Feb 2025
• Castruccio Castracani C, Breda L, Papp TE, Guerra A, Radaelli E, Assenmacher CA, Finesso G, Mui BL, Tam YK, Fontana S, Riganti C, Fiorito V, Petrillo S, Tolosano E, Parhiz H, Rivella S. : An erythroid-specific lentiviral vector improves anemia and iron metabolism in a new model of XLSA Blood 145 : 98-113, Jan 2025
• Omo-Lamai S, Wang Y, Patel MN, Milosavljevic A, Zuschlag D, Poddar S, Wu J, Wang L, Dong F, Espy C, Majumder A, Essien EO, Shen M, Channer B, Papp TE, Tobin M, Maheshwari R, Jeong S, Patel S, Shah A, Murali S, Chase LS, Zamora ME, Arral ML, Marcos-Contreras OA, Myerson JW, Hunter CA, Discher D, Gaskill PJ, Tsourkas A, Muzykantov VR, Brodsky I, Shin S, Whitehead KA, Parhiz H, Katzen J, Miner JJ, Trauner D, Brenner JS. : Limiting endosomal damage sensing reduces inflammation triggered by lipid nanoparticle endosomal escape Nat Nanotechnol 2025
• Chappell ME, Breda L, Tricoli L, Guerra A, Jarocha D, Castruccio Castracani C, Papp TE, Tanaka N, Hamilton N, Triebwasser MP, Ghiaccio V, Fedorky MT, Gollomp KL, Bochenek V, Roche AM, Everett JK, Cook EJ, Bushman FD, Teawtrakul N, Glentis S, Kattamis A, Mui BL, Tam YK, Weissman D, Abdulmalik O, Parhiz H, Rivella S. : Use of HSC-targeted LNP to generate a mouse model of lethal α-thalassemia and treatment via lentiviral gene therapy Blood 144 : 1633-1645, Oct 2024
• Mukalel AJ, Hamilton AG, Billingsley MM, Li J, Thatte AS, Han X, Safford HC, Padilla MS, Papp T, Parhiz H, Weissman D, Mitchell MJ. : Oxidized mRNA Lipid Nanoparticles for In Situ Chimeric Antigen Receptor Monocyte Engineering Adv Funct Mater 34 : 2312038, Jul 2024