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Nicholas K. Brown, PhD

Associate Professor of Clinical Pathology and Laboratory Medicine

  • Associate Director, Histocompatibility Testing Laboratory, Hospital of the University of Pennsylvania

Department: Pathology and Laboratory Medicine


Contact Information

Founders 7019
3400 Spruce Street

Philadelphia, PA 19104
Office: 215-615-7789
Email: nicholas.brown@pennmedicine.upenn.edu


I3H Keywords

  • Transplantation Immunity

Publications

Pubmed Link


Links


Education

  • BA (Biology)
    Kalamazoo College, Kalamazoo, MI, 2000
  • PhD (Immunology and Microbiology (incl. Research Assistant role))
    Wayne State University School of Medicine, Detroit, MI, 2007

Post-Graduate Training

  • Fellow, Transplant Immunology
    The University of Chicago, 2014 - 2016
  • Fellow, Center for Cancer & Immunology Research
    Children's National Medical Center, 2013 - 2014
  • Fellow, Immunotherapy
    The University of Michigan, 2010 - 2013
  • Postdoctoral Scholar, Dept. of Pathology
    The University of Chicago, 2008 - 2010

Certifications

  • American College of Histocompatibility and Immunogenetics, 2016

Selected Publications

  • N.K. Brown, L. Gragert, A.N. Paynter, K. McCullough, ... M. Kamoun : Donor specific antibodies to DQ antigens are rare in DR antigen matched kidney transplants Human Immunology 85(Supplement) September 2024 Notes: Article 110940
  • A.N. Paynter, M. Kamoun, N.K. Brown, R.J. Urbanowicz, ... L. Gragert : Profiling performance of high-resolution HLA imputation with complementary metrics and visualizations using an open-source validation framework Human Immunology 85(supplement) September 2024 Notes: Article 110922
  • N.K. Brown, R. Bray, G. Morris, L. Gragert : Reporting HLA antigens for the DRB3/4/5 Locus at the first field in UNet would decrease rates of deceased donor offer refusal Human Immunology 85(Supplement) September 2024 Notes: Article 110919
  • Olga A. Timofeeva and Nicholas K. Brown : The ASHI Standards for Accredited Laboratories: How and Why They Change ASHI Quarterly Q3 : 26-32, September 2024
  • McCullough K., Gragert L., Urbanowicz R., Brown N., Kamoun M. : Interaction between HLA-DRB1 and DQB1 Antigen Mismatches as Predictors of Kidney Allograft Failure American Journal of Transplantation 24(6, Supplement 1) : A115, June 2024
  • Nicholas K. Brown and Chang Liu : HLA-DQ Associated Autoimmunity ASHI Quarterly Q2 2024 : 10-14, June 2024
  • Nicholas K. Brown : The Data Standards Hackathons (DaSH) for Next Generation Sequencing ASHI Quarterly Q1 2024 : 8-12, March 2024
  • Misra MK, Brown NK, Marino SG. : Next-generation sequencing identifies two novel HLA-DPB1 alleles: HLA-DPB1*1069:01 and DPB1*1072:01. HLA 103(2) Feb 2024 Notes: doi: 10.1111/tan.15368.
  • D. Bell, M. Personius, V. McCarro, T. Bui, N. Brown : The DRB4*03:01N allele confounds NGS typing software Human Immunology 84(Supplement) : P109, September 2023
  • E. Kamieniecki, N. Brown : An R program for automatic quality control of single antigen bead assays via Levey-Jennings charts Human Immunology 84(Supplement) : P116, September 2023