Key Publications
Michael Cancro (1949–2025)
Mark J. Shlomchik and David Allman - Immunity 58, April 8, 2025 PMID is: 40203802
Read Moreabout Michael Cancro (1949–2025)Continuous expression of TOX safeguards exhausted CD8 T cell epigenetic fate.
Huang YJ, Ngiow SF, Baxter AE, Manne S, Park SL, Wu JE, Khan O, Giles JR, Wherry EJ. Sci Immunol. 2025 Mar 7;10(105):eado3032. doi: 10.1126/sciimmunol.ado3032. Epub 2025 Mar 7. PMID: 40053604
Read Moreabout Continuous expression of TOX safeguards exhausted CD8 T cell epigenetic fate.Tick feeding or vaccination with tick antigens elicits immunity to the Ixodes scapularis exoproteome in guinea pigs and humans.
Hart TM, Cui Y, Telford SR, Marín-López A, Calloway K, Dai Y, Matias J, DePonte K, Jaycox J, DeBlasio M, Hoornstra D, Belperron AA, Cibichakravarthy B, Johnson EE, Alameh MG, Dwivedi G, Hovius JWR, Bockenstedt LK, Weissman D, Ring...
Read Moreabout Tick feeding or vaccination with tick antigens elicits immunity to the Ixodes scapularis exoproteome in guinea pigs and humans.Assessing the oncogenic risk: the long-term safety of autologous chimeric antigen receptor T cells.
Baker DJ, Levine BL, June CH. Lancet. 2025 Mar 1;405(10480):751-754. doi: 10.1016/S0140-6736(25)00039-X. PMID: 40023653
Read Moreabout Assessing the oncogenic risk: the long-term safety of autologous chimeric antigen receptor T cells.Immune targeting and host-protective effects of the latent stage of Toxoplasma gondii.
Eberhard JN, Shallberg LA, Winn A, Chandrasekaran S, Giuliano CJ, Merritt EF, Willis E, Konradt C, Christian DA, Aldridge DL, Bunkofske ME, Jacquet M, Dzierszinski F, Katifori E, Lourido S, Koshy AA, Hunter CA. Nat Microbiol. 2025 Mar 27. doi:...
Read Moreabout Immune targeting and host-protective effects of the latent stage of Toxoplasma gondii.Immune history shapes human antibody responses to H5N1 influenza viruses.
Garretson TA, Liu J, Li SH, Scher G, Santos JJS, Hogan G, Vieira MC, Furey C, Atkinson RK, Ye N, Ort JT, Kim K, Hernandez KA, Eilola T, Schultz DC, Cherry S, Cobey S, Hensley SE. Nat Med...
Read Moreabout Immune history shapes human antibody responses to H5N1 influenza viruses.Modulation of lipid nanoparticle-formulated plasmid DNA drives innate immune activation promoting adaptive immunity.
Tursi NJ, Tiwari S, Bedanova N, Kannan T, Parzych E, Okba N, Liaw K, Sárközy A, Livingston C, Trullen MI, Gary EN, Vadovics M, Laenger N, Londregan J, Khan MS, Omo-Lamai S, Muramatsu H, Blatney K, Hojecki C, Machado V,...
Read Moreabout Modulation of lipid nanoparticle-formulated plasmid DNA drives innate immune activation promoting adaptive immunity.The epigenetic landscape of fate decisions in T cells.
Jay A, Pondevida CM, Vahedi G. Nat Immunol. 2025 Mar 19. doi: 10.1038/s41590-025-02113-x. Online ahead of print. PMID: 40108419
Read Moreabout The epigenetic landscape of fate decisions in T cells.B cell stimulation changes the structure and higher-order organization of the inactive X chromosome.
Sierra I, Toothacre NE, van der Weide RH, Lovell CD, Nguyen SC, Barnett RJ, Cook AL, Ryu HS, Pyfrom S, Wang H, Beiting D, Philips-Cremins JE, Joyce EF, Anguera MC. Cell Rep. 2025 Mar 25;44(3):115351. doi: 10.1016/j.celrep.2025.115351. Epub...
Read Moreabout B cell stimulation changes the structure and higher-order organization of the inactive X chromosome.Bacteriocin production facilitates nosocomial emergence of vancomycin-resistant Enterococcus faecium.
Mills EG, Hewlett K, Smith AB, Griffith MP, Pless L, Sundermann AJ, Harrison LH, Zackular JP, Van Tyne D. Nat Microbiol. 2025 Mar 21. doi: 10.1038/s41564-025-01958-0. Online ahead of print. PMID: 40119148
Read Moreabout Bacteriocin production facilitates nosocomial emergence of vancomycin-resistant Enterococcus faecium.A patient-derived T cell lymphoma biorepository uncovers pathogenetic mechanisms and host-related therapeutic vulnerabilities.
Fiore D, Cappelli LV, Zhaoqi L, Kotlov N, Sorokina M, Phillip J, Zumbo P, Yoffe L, Ghione P, Wang A, Han X, Taylor A, Chiu W, Fragliasso V, Tabbo F, Zamponi N, Di Siervi N, Kayembe C, Medico G, Patel...
Read Moreabout A patient-derived T cell lymphoma biorepository uncovers pathogenetic mechanisms and host-related therapeutic vulnerabilities.Targeting pathogenic interferon-stimulated gene RSAD2 improves pregnancy outcomes in systemic lupus erythematosus models.
Negatu SG, Jurado KA. Cell Rep Med. 2025 Mar 18;6(3):102034. doi: 10.1016/j.xcrm.2025.102034. PMID: 40107239
Read Moreabout Targeting pathogenic interferon-stimulated gene RSAD2 improves pregnancy outcomes in systemic lupus erythematosus models.Therapeutic activation of IL-22-producing innate lymphoid cells enhances host defenses to Clostridioides difficile infection.
Mears KS, Denny JE, Maslanka JR, Mdluli NV, Hulit EN, Matsuda R, Furth EE, Buffie CG, Abt MC. Cell Rep. 2025 Mar 25;44(4):115438. doi: 10.1016/j.celrep.2025.115438. Online ahead of print. PMID: 40138315
Read Moreabout Therapeutic activation of IL-22-producing innate lymphoid cells enhances host defenses to Clostridioides difficile infection.CAR-macrophage therapy for HER2-overexpressing advanced solid tumors: a phase 1 trial.
Reiss KA, Angelos MG, Dees EC, Yuan Y, Ueno NT, Pohlmann PR, Johnson ML, Chao J, Shestova O, Serody JS, Schmierer M, Kremp M, Ball M, Qureshi R, Schott BH, Sonawane P, DeLong SC, Christiano M, Swaby RF, Abramson S,...
Read Moreabout CAR-macrophage therapy for HER2-overexpressing advanced solid tumors: a phase 1 trial.CryoEM structure of an MHC-I/TAPBPR peptide-bound intermediate reveals the mechanism of antigen proofreading.
Sun Y, Pumroy RA, Mallik L, Chaudhuri A, Wang C, Hwang D, Danon JN, Dasteh Goli K, Moiseenkova-Bell VY, Sgourakis NG. Proc Natl Acad Sci U S A. 2025 Jan 14;122(2):e2416992122. doi: 10.1073/pnas.2416992122. Epub 2025 Jan 9. PMID: 39786927
Read Moreabout CryoEM structure of an MHC-I/TAPBPR peptide-bound intermediate reveals the mechanism of antigen proofreading.Time to HIV viral rebound and frequency of post-treatment control after analytical interruption of antiretroviral therapy: an individual data-based meta-analysis of 24 prospective studies.
Gunst JD, Gohil J, Li JZ, Bosch RJ, White Catherine Seamon A, Chun TW, Mothe B, Gittens K, Praiss L, De Scheerder MA, Vandekerckhove L, Escandón K, Thorkelson A, Schacker T, SenGupta D, Brander C, Papasavvas E, Montaner LJ,...
Read Moreabout Time to HIV viral rebound and frequency of post-treatment control after analytical interruption of antiretroviral therapy: an individual data-based meta-analysis of 24 prospective studies.The global H5N1 influenza panzootic in mammals.
Peacock TP, Moncla L, Dudas G, VanInsberghe D, Sukhova K, Lloyd-Smith JO, Worobey M, Lowen AC, Nelson MI. Nature. 2025 Jan;637(8045):304-313. doi: 10.1038/s41586-024-08054-z. Epub 2024 Sep 24. PMID: 39317240
Read Moreabout The global H5N1 influenza panzootic in mammals.Dopaminergic signaling to ventral striatum neurons initiates sniffing behavior.
Johnson NL, Cotelo-Larrea A, Stetzik LA, Akkaya UM, Zhang Z, Gadziola MA, Varga AG, Ma M, Wesson DW. Nat Commun. 2025 Jan 2;16(1):336. doi: 10.1038/s41467-024-55644-6. PMID: 39747223
Read Moreabout Dopaminergic signaling to ventral striatum neurons initiates sniffing behavior.Brain-wide neuronal circuit connectome of human glioblastoma.
Sun Y, Wang X, Zhang DY, Zhang Z, Bhattarai JP, Wang Y, Park KH, Dong W, Hung YF, Yang Q, Zhang F, Rajamani K, Mu S, Kennedy BC, Hong Y, Galanaugh J, Sambangi A, Kim SH, Wheeler G, Gonçalves T,...
Read Moreabout Brain-wide neuronal circuit connectome of human glioblastoma.SLE B cells take an extrafollicular detour after mRNA vaccination.
Apostolidis SA, Locci M. Nat Immunol. 2025 Jan;26(1):4-6. doi: 10.1038/s41590-024-02035-0. PMID: 39730724
Read Moreabout SLE B cells take an extrafollicular detour after mRNA vaccination.