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    Erin Zwak/Brodsky Lab & Penn Vet Imaging Core - Murine macrophages infected with Yersinia pseudo tuberculosis. Blue indicates the cell, red is a mitochondrial stain, green is a stain for Yersinia secreted effector proteins.

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    Claudio Giraudo - Polarization of lytic granules to the immunological synapse during the cytolytic process of human CD8 lymphocytes against cancer cells.

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    Gretchen Harms, Hunter lab - Stylized images of CD8+ T cells looking at differential localization of the transcription factor T-bet in mouse cells after infection with the parasite Toxoplasma gondii, using the Amnis ImageStream. In the cell in the first and third box, T-bet (red) does not co-localize with DAPI (blue), indicating that it is cytoplasmic, whereas in the cell in the second and fourth box, T-bet does co-localize with DAPI, indicating that it is nuclear. David Christian assisted in obtaining these images.


Our Mission

*Advance our knowledge of the basic immunology of inflammation, autoimmunity, cancer, transplantation and infection and to translate this new knowledge to novel strategies for diagnosis, prevention and therapeutic intervention. 

*Foster collaborations and further strengthen interactions among the Penn community of immunologists.

Spotlights on IFI

Congratulations to Igor Brodsky, PhD and Rahul Kohli, MD, PhD for receiving the Investigators in the Pathogenesis of Infectious Disease Award from the Burroughs Wellcome Fund.

Congratulations to the 2015 IFI Pilot Awardees:

Jorge Henao Mejia, MD, PhD, Assistant Professor of Pathology and Laboratory Medicine
LincRNAs in Inflammatory Bowel Disease

Matthew Levine, MD, PhD, Assistant Professor of Surgery
Mechanistic High Throughput Screening to Identify Means of HDAC2 Deletion-Associated Ischemia Tolerance