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    Laura McLane and Mike Betts -Purified human CD8 T-cells were stained with a-T-bet (green), a-Lamin A (pink), and DAPI (blue) and imaged on a multilaser-based spinning disk confocal microscope (Zeiss). T-bet can be localized to both the nuclear and cytoplasmic compartments of specific subsets of human CD8 T-cells.

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    3D image of the inflamed meningeal membrane of a CX3CR1-GFP reporter mouse infected with Toxoplasma gondii. The dura mater that surrounds the brain is blue, blood vessels are labeled red and microglia and macrophages are green. Contributors for image are ChristophKonradt and Chris Hunter.

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    Time series of cells expressing GFP-tagged ebola viral protein VP40, pseudocolored as a fluorescence intensity heatmap. The contributors for image are: Gordon Ruthel, Xiaohong Liu, Ron Harty, and Bruce Freedman.

Welcome

Our Mission

*Advance our knowledge of the basic immunology of inflammation, autoimmunity, cancer, transplantation and infection and to translate this new knowledge to novel strategies for diagnosis, prevention and therapeutic intervention. 

*Foster collaborations and further strengthen interactions among the Penn community of immunologists.

Spotlights on IFI

Congratulations to Igor Brodsky, PhD and Rahul Kohli, MD, PhD for receiving the Investigators in the Pathogenesis of Infectious Disease Award from the Burroughs Wellcome Fund.


Congratulations to the 2015 IFI Pilot Awardees:

Jorge Henao Mejia, MD, PhD, Assistant Professor of Pathology and Laboratory Medicine
LincRNAs in Inflammatory Bowel Disease

Matthew Levine, MD, PhD, Assistant Professor of Surgery
Mechanistic High Throughput Screening to Identify Means of HDAC2 Deletion-Associated Ischemia Tolerance