Publications

Seizures exacerbate excitatory: inhibitory imbalance in Alzheimer's disease and 5XFAD mice.
Brain : a journal of neurology. 2024 Jun 3;147(6):2169-2184; Authors: Barbour AJ, Gourmaud S, Lancaster E, Li X, Stewart DA, Hoag KF, Irwin DJ, Talos DM, Jensen FE

Cannabidiol attenuates seizure susceptibility and behavioural deficits in adult CDKL5(R59X) knock-in mice.
The European journal of neuroscience. 2024 Jun;59(12):3337-3352 Epub 2024 Apr 23; Authors: Li X, Yennawar M, Wiest A, O'Brien WT, Babrowicz B, White RS, Talos DM, Jensen FE

Posttraumatic Epilepsy and Dementia Risk.
JAMA neurology. 2024 Feb 26;81(4):346-53; Authors: Schneider ALC, Law CA, Gottesman RF, Krauss G, Huang J, Kucharska-Newton A, Jensen FE, Gugger JJ, Diaz-Arrastia R, Johnson EL

Reversible synaptic adaptations in a subpopulation of murine hippocampal neurons following early-life seizures.
The Journal of clinical investigation. 2024 Jan 16;134(5); Authors: Xing B, Barbour AJ, Vithayathil J, Li X, Dutko S, Fawcett-Patel J, Lancaster E, Talos DM, Jensen FE

Recognizing and Responding to the Needs of Future Child and Adult Neurology Care Through the Evolution of Residency Training.
Annals of neurology. 2023 Dec;94(6):1005-1007 Epub 2023 Oct 17; Authors: McArthur JC, Augustine EF, Carmichael ST, Ferriero DM, Jensen FE, Jeste SS, Jordan LC, Llinas RH, Schlaggar BL, Sun LR, Pomeroy SL

Shifting the trajectory of therapeutic development for neurological and psychiatric disorders.
Science translational medicine. 2023 Nov;15(720):eadg4775 Epub 2023 Nov 1; Authors: Krainc D, Martin WJ, Casey B, Jensen FE, Tishkoff S, Potter WZ, Hyman SE

Discovery of E2730, a novel selective uncompetitive GAT1 inhibitor, as a candidate for anti-seizure medication.
Epilepsia open. 2023 Sep;8(3):834-845 Epub 2023 May 18; Authors: Fukushima K, Higashiyama H, Kazuta Y, Hashimoto K, Watanabe N, Furuya Y, Ito Y, Wu T, Kosasa T, Talos DM, Song Y, Roberts NS, Jensen FE, Hanada T, Ido K

Anti-seizure efficacy of perampanel in two established rodent models of early-life epilepsy.
Epilepsy & behavior : E&B. 2023 Jun;143:109194 Epub 2023 Apr 27; Authors: Roberts NS, Handy MJ, Ito Y, Hashimoto K, Jensen FE, Talos DM

Optical Redox Imaging of Ex Vivo Hippocampal Tissue Reveals Age-Dependent Alterations in the 5XFAD Mouse Model of Alzheimer's Disease.
Metabolites. 2022 Aug 25;12(9); Authors: Xu HN, Gourmaud S, Podsednik A, Li X, Zhao H, Jensen FE, Talos DM, Li LZ

The role of mTORC1 activation in seizure-induced exacerbation of Alzheimer's disease.
Brain : a journal of neurology. 2022 Mar 29;145(1):324-339; Authors: Gourmaud S, Stewart DA, Irwin DJ, Roberts N, Barbour AJ, Eberwine G, O'Brien WT, Vassar R, Talos DM, Jensen FE

Dysregulation of GABAA Receptor-Mediated Neurotransmission during the Auditory Cortex Critical Period in the Fragile X Syndrome Mouse Model.
Cerebral cortex (New York, N.Y. : 1991). 2021 Nov 23;32(1):197-215; Authors: Song YJ, Xing B, Barbour AJ, Zhou C, Jensen FE

Strengthened through Diversity: A Blueprint for Organizational Change.
Annals of neurology. 2021 Oct;90(4):524-536 Epub 2021 Aug 5; Authors: Willis A, Skolarus LE, Faigle R, Menon U, Redwine H, Brown AM, Felton E, Mendizabal A, Nath A, Jensen F, McArthur JC

Altered hippocampal dendritic spine maturation after hypoxia-induced seizures in neonatal rats.
Molecular and cellular neurosciences. 2021 Jun;113:103629 Epub 2021 May 18; Authors: Lippman-Bell JJ, Handy M, Nieder CG, Getzfread M, Jensen FE

Adults with Cerebral Palsy Require Ongoing Neurologic Care: A Systematic Review.
Annals of neurology. 2021 May;89(5):860-871 Epub 2021 Feb 26; Authors: Smith SE, Gannotti M, Hurvitz EA, Jensen FE, Krach LE, Kruer MC, Msall ME, Noritz G, Rajan DS, Aravamuthan BR

A Pilot Randomized, Controlled, Double-Blind Trial of Bumetanide to Treat Neonatal Seizures.
Annals of neurology. 2021 Feb;89(2):327-340 Epub 2020 Dec 3; Authors: Soul JS, Bergin AM, Stopp C, Hayes B, Singh A, Fortuno CR, O'Reilly D, Krishnamoorthy K, Jensen FE, Rofeberg V, Dong M, Vinks AA, Wypij D, Staley KJ, Boston Bumetanide Trial Group

Opportunities and limitations of genetically modified nonhuman primate models for neuroscience research.
Proceedings of the National Academy of Sciences of the United States of America. 2020 Sep 29;117(39):24022-24031 Epub 2020 Aug 19; Authors: Feng G, Jensen FE, Greely HT, Okano H, Treue S, Roberts AC, Fox JG, Caddick S, Poo MM, Newsome WT, Morrison JH

Alzheimer-like amyloid and tau alterations associated with cognitive deficit in temporal lobe epilepsy.
Brain : a journal of neurology. 2020 Jan 1;143(1):191-209; Authors: Gourmaud S, Shou H, Irwin DJ, Sansalone K, Jacobs LM, Lucas TH, Marsh ED, Davis KA, Jensen FE, Talos DM

AMPA Receptor Dysregulation and Therapeutic Interventions in a Mouse Model of CDKL5 Deficiency Disorder.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 2019 Jun 12;39(24):4814-4828 Epub 2019 Apr 5; Authors: Yennawar M, White RS, Jensen FE

Closing the Sex Divide in the Emerging Field of Neurology.
JAMA neurology. 2018 Aug 1;75(8):920-921; Authors: Jensen FE

Regulation of seizure-induced MeCP2 Ser421 phosphorylation in the developing brain.
Neurobiology of disease. 2018 Aug;116:120-130 Epub 2018 May 5; Authors: Rosenberg EC, Lippman-Bell JJ, Handy M, Soldan SS, Rakhade S, Hilario-Gomez C, Folweiler K, Jacobs L, Jensen FE

Electroencephalographic monitoring for seizure identification and prognosis in term neonates.
Seminars in fetal & neonatal medicine. 2018 Jun;23(3):168-174 Epub 2018 Jan 17; Authors: Massey SL, Jensen FE, Abend NS

Early Seizures Prematurely Unsilence Auditory Synapses to Disrupt Thalamocortical Critical Period Plasticity.
Cell reports. 2018 May 29;23(9):2533-2540; Authors: Sun H, Takesian AE, Wang TT, Lippman-Bell JJ, Hensch TK, Jensen FE

Mechanistic target of rapamycin complex 1 and 2 in human temporal lobe epilepsy.
Annals of neurology. 2018 Feb;83(2):311-327 Epub 2018 Feb 15; Authors: Talos DM, Jacobs LM, Gourmaud S, Coto CA, Sun H, Lim KC, Lucas TH, Davis KA, Martinez-Lage M, Jensen FE

Identification and characterization of outcome measures reported in animal models of epilepsy: Protocol for a systematic review of the literature-A TASK2 report of the AES/ILAE Translational Task Force of the ILAE.
Epilepsia. 2017 Nov;58 Suppl 4:68-77; Authors: Simonato M, Iyengar S, Brooks-Kayal A, Collins S, Depaulis A, Howells DW, Jensen F, Liao J, Macleod MR, Patel M, Potschka H, Walker M, Whittemore V, Sena ES

18-month outcomes of heterologous bilateral hand transplantation in a child: a case report.
The Lancet. Child & adolescent health. 2017 Sep;1(1):35-44 Epub 2017 Jul 18; Authors: Amaral S, Kessler SK, Levy TJ, Gaetz W, McAndrew C, Chang B, Lopez S, Braham E, Humpl D, Hsia M, Ferry KA, Xu X, Elder D, Lefkowitz D, Feudtner C, Thibaudeau S, Lin IC, Kovach SJ, Schwartz ES, Bozentka D, Carrigan R, Steinberg D, Kanchwala S, Zlotolow DA, Kozin S, Jensen FE, Bryant PR, Shaked A, Levine MH, Levin LS

Upregulation of cystathionine β-synthase and p70S6K/S6 in neonatal hypoxic ischemic brain injury.
Brain pathology (Zurich, Switzerland). 2017 Jul;27(4):449-458 Epub 2016 Aug 28; Authors: Lechpammer M, Tran YP, Wintermark P, Martínez-Cerdeño V, Krishnan VV, Ahmed W, Berman RF, Jensen FE, Nudler E, Zagzag D

Developmental toxicity of nicotine: A transdisciplinary synthesis and implications for emerging tobacco products.
Neuroscience and biobehavioral reviews. 2017 Jan;72:176-189 Epub 2016 Nov 24; Authors: England LJ, Aagaard K, Bloch M, Conway K, Cosgrove K, Grana R, Gould TJ, Hatsukami D, Jensen F, Kandel D, Lanphear B, Leslie F, Pauly JR, Neiderhiser J, Rubinstein M, Slotkin TA, Spindel E, Stroud L, Wakschlag L

Early-life seizures alter synaptic calcium-permeable AMPA receptor function and plasticity.
Molecular and cellular neurosciences. 2016 Oct;76:11-20 Epub 2016 Aug 10; Authors: Lippman-Bell JJ, Zhou C, Sun H, Feske JS, Jensen FE

Bioresorbable silicon electronics for transient spatiotemporal mapping of electrical activity from the cerebral cortex.
Nature materials. 2016 Jul;15(7):782-791 Epub 2016 Apr 18; Authors: Yu KJ, Kuzum D, Hwang SW, Kim BH, Juul H, Kim NH, Won SM, Chiang K, Trumpis M, Richardson AG, Cheng H, Fang H, Thomson M, Bink H, Talos D, Seo KJ, Lee HN, Kang SK, Kim JH, Lee JY, Huang Y, Jensen FE, Dichter MA, Lucas TH, Viventi J, Litt B, Rogers JA

Dysregulation of FMRP/mTOR Signaling Cascade in Hypoxic-Ischemic Injury of Premature Human Brain.
Journal of child neurology. 2016 Mar;31(4):426-32 Epub 2015 Aug 3; Authors: Lechpammer M, Wintermark P, Merry KM, Jackson MC, Jantzie LL, Jensen FE

Models of hypoxia and ischemia-induced seizures.
Journal of neuroscience methods. 2016 Feb 15;260:252-60 Epub 2015 Oct 3; Authors: Sun H, Juul HM, Jensen FE

Brain Perfusion Is Increased at Term in the White Matter of Very Preterm Newborns and Newborns with Congenital Heart Disease: Does this Reflect Activated Angiogenesis?
Neuropediatrics. 2015 Oct;46(5):344-51 Epub 2015 Sep 4; Authors: Wintermark P, Lechpammer M, Kosaras B, Jensen FE, Warfield SK

Neonatal seizures alter NMDA glutamate receptor GluN2A and 3A subunit expression and function in hippocampal CA1 neurons.
Frontiers in cellular neuroscience. 2015;9:362 Epub 2015 Sep 23; Authors: Zhou C, Sun H, Klein PM, Jensen FE

Acute seizure suppression by transcranial direct current stimulation in rats.
Annals of clinical and translational neurology. 2015 Aug;2(8):843-56 Epub 2015 Jul 3; Authors: Dhamne SC, Ekstein D, Zhuo Z, Gersner R, Zurakowski D, Loddenkemper T, Pascual-Leone A, Jensen FE, Rotenberg A

Increased Brain Perfusion Persists over the First Month of Life in Term Asphyxiated Newborns Treated with Hypothermia: Does it Reflect Activated Angiogenesis?
Translational stroke research. 2015 Jun;6(3):224-33 Epub 2015 Jan 27; Authors: Shaikh H, Lechpammer M, Jensen FE, Warfield SK, Hansen AH, Kosaras B, Shevell M, Wintermark P

Chloride cotransporter NKCC1 inhibitor bumetanide protects against white matter injury in a rodent model of periventricular leukomalacia.
Pediatric research. 2015 Apr;77(4):554-62 Epub 2015 Jan 13; Authors: Jantzie LL, Hu MY, Park HK, Jackson MC, Yu J, Maxwell JR, Jensen FE

Developmental expression of N-methyl-D-aspartate (NMDA) receptor subunits in human white and gray matter: potential mechanism of increased vulnerability in the immature brain.
Cerebral cortex (New York, N.Y. : 1991). 2015 Feb;25(2):482-95 Epub 2013 Sep 17; Authors: Jantzie LL, Talos DM, Jackson MC, Park HK, Graham DA, Lechpammer M, Folkerth RD, Volpe JJ, Jensen FE

Found in translation: training the next generation of translational neuroscientists.
Neuron. 2014 Nov 5;84(3):542-5; Authors: Jensen FE, Amara SG

The challenge and promise of anti-epileptic therapy development in animal models.
The Lancet. Neurology. 2014 Sep;13(9):949-60 Epub 2014 Aug 10; Authors: Simonato M, Brooks-Kayal AR, Engel J Jr, Galanopoulou AS, Jensen FE, Moshé SL, O'Brien TJ, Pitkanen A, Wilcox KS, French JA

Lestaurtinib (CEP-701) attenuates "second hit" kainic acid-induced seizures following early life hypoxic seizures.
Epilepsy research. 2014 May;108(4):806-10 Epub 2014 Jan 31; Authors: Obeid M, Rosenberg EC, Klein PM, Jensen FE

Subunit composition of glutamate and gamma-aminobutyric acid receptors in status epilepticus.
Epilepsy research. 2014 May;108(4):605-15 Epub 2014 Feb 2; Authors: Loddenkemper T, Talos DM, Cleary RT, Joseph A, Sánchez Fernández I, Alexopoulos A, Kotagal P, Najm I, Jensen FE

α5-GABAA receptors negatively regulate MYC-amplified medulloblastoma growth.
Acta neuropathologica. 2014 Apr;127(4):593-603 Epub 2013 Nov 7; Authors: Sengupta S, Weeraratne SD, Sun H, Phallen J, Rallapalli SK, Teider N, Kosaras B, Amani V, Pierre-Francois J, Tang Y, Nguyen B, Yu F, Schubert S, Balansay B, Mathios D, Lechpammer M, Archer TC, Tran P, Reimer RJ, Cook JM, Lim M, Jensen FE, Pomeroy SL, Cho YJ

Suppression of motor cortical excitability in anesthetized rats by low frequency repetitive transcranial magnetic stimulation.
PloS one. 2014;9(3):e91065 Epub 2014 Mar 19; Authors: Muller PA, Dhamne SC, Vahabzadeh-Hagh AM, Pascual-Leone A, Jensen FE, Rotenberg A

Epilepsy in 2013: progress across the spectrum of epilepsy research.
Nature reviews. Neurology. 2014 Feb;10(2):63-4 Epub 2014 Jan 14; Authors: Jensen FE

Rasmussen's encephalitis: clinical features, pathobiology, and treatment advances.
The Lancet. Neurology. 2014 Feb;13(2):195-205; Authors: Varadkar S, Bien CG, Kruse CA, Jensen FE, Bauer J, Pardo CA, Vincent A, Mathern GW, Cross JH

Authors' response to letter by A. Mazarati.
Epilepsia. 2013 Dec;54(12):2229-30; Authors: Brooks-Kayal AR, Bath KG, Berg AT, Galanopoulou AS, Holmes GL, Jensen FE, Kanner AM, O'Brien TJ, Whittemore VH, Winawer MR, Patel M, Scharfman HE

Perfusion Imaging of Focal Cortical Dysplasia Using Arterial Spin Labeling: Correlation With Histopathological Vascular Density.
Journal of child neurology. 2013 Nov;28(11):1474-1482 Epub 2013 May 21; Authors: Wintermark P, Lechpammer M, Warfield SK, Kosaras B, Takeoka M, Poduri A, Madsen JR, Bergin AM, Whalen S, Jensen FE

AMPA receptor antagonist NBQX attenuates later-life epileptic seizures and autistic-like social deficits following neonatal seizures.
Epilepsia. 2013 Nov;54(11):1922-32 Epub 2013 Oct 1; Authors: Lippman-Bell JJ, Rakhade SN, Klein PM, Obeid M, Jackson MC, Joseph A, Jensen FE

Gene expression profiling of a hypoxic seizure model of epilepsy suggests a role for mTOR and Wnt signaling in epileptogenesis.
PloS one. 2013;8(9):e74428 Epub 2013 Sep 27; Authors: Theilhaber J, Rakhade SN, Sudhalter J, Kothari N, Klein P, Pollard J, Jensen FE

Considering a career in neurology research? Heed these words.
Annals of neurology. 2013 Sep;74(3):A12; Authors: Jensen FE, Paulson HL, Bar-Or A

Issues related to development of antiepileptogenic therapies.
Epilepsia. 2013 Aug;54 Suppl 4(0 4):35-43; Authors: Pitkänen A, Nehlig A, Brooks-Kayal AR, Dudek FE, Friedman D, Galanopoulou AS, Jensen FE, Kaminski RM, Kapur J, Klitgaard H, Löscher W, Mody I, Schmidt D

Issues related to symptomatic and disease-modifying treatments affecting cognitive and neuropsychiatric comorbidities of epilepsy.
Epilepsia. 2013 Aug;54 Suppl 4(0 4):44-60; Authors: Brooks-Kayal AR, Bath KG, Berg AT, Galanopoulou AS, Holmes GL, Jensen FE, Kanner AM, O'Brien TJ, Whittemore VH, Winawer MR, Patel M, Scharfman HE

Epilepsy biomarkers.
Epilepsia. 2013 Aug;54 Suppl 4(0 4):61-9; Authors: Engel J Jr, Pitkänen A, Loeb JA, Dudek FE, Bertram EH 3rd, Cole AJ, Moshé SL, Wiebe S, Jensen FE, Mody I, Nehlig A, Vezzani A

The tower of Babel: survey on concepts and terminology in electrical status epilepticus in sleep and continuous spikes and waves during sleep in North America.
Epilepsia. 2013 Apr;54(4):741-50 Epub 2012 Nov 16; Authors: Fernández IS, Chapman KE, Peters JM, Kothare SV, Nordli DR Jr, Jensen FE, Berg AT, Loddenkemper T

Mammalian target of rapamycin complex 1 activation negatively regulates Polo-like kinase 2-mediated homeostatic compensation following neonatal seizures.
Proceedings of the National Academy of Sciences of the United States of America. 2013 Mar 26;110(13):5199-204 Epub 2013 Mar 11; Authors: Sun H, Kosaras B, Klein PM, Jensen FE

Antiepileptic effects of levetiracetam in a rodent neonatal seizure model.
Pediatric research. 2013 Jan;73(1):24-30 Epub 2012 Nov 8; Authors: Talos DM, Chang M, Kosaras B, Fitzgerald E, Murphy A, Folkerth RD, Jensen FE

Bumetanide enhances phenobarbital efficacy in a rat model of hypoxic neonatal seizures.
PloS one. 2013;8(3):e57148 Epub 2013 Mar 11; Authors: Cleary RT, Sun H, Huynh T, Manning SM, Li Y, Rotenberg A, Talos DM, Kahle KT, Jackson M, Rakhade SN, Berry G, Jensen FE

Glutamate receptor 1 phosphorylation at serine 831 and 845 modulates seizure susceptibility and hippocampal hyperexcitability after early life seizures.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 2012 Dec 5;32(49):17800-12; Authors: Rakhade SN, Fitzgerald EF, Klein PM, Zhou C, Sun H, Huganir RL, Jensen FE

Testimonies submitted for the Institute of Medicine report: epilepsy across the spectrum: promoting health and understanding.
Epilepsy & behavior : E&B. 2012 Dec;25(4):634-61 Epub 2012 Nov 14; Authors: Austin JK, Hesdorffer DC, Liverman CT, Schultz AM, Testimony Group

Finding a better drug for epilepsy: antiepileptogenesis targets.
Epilepsia. 2012 Nov;53(11):1868-76 Epub 2012 Oct 12; Authors: Kobow K, Auvin S, Jensen F, Löscher W, Mody I, Potschka H, Prince D, Sierra A, Simonato M, Pitkänen A, Nehlig A, Rho JM

Introduction to institute of medicine report: epilepsy across the spectrum: promoting health and understanding.
Epilepsy currents. 2012 Nov;12(6):243-4; Authors: Jacobs M, Jensen FE

Altered inhibition in tuberous sclerosis and type IIb cortical dysplasia.
Annals of neurology. 2012 Apr;71(4):539-51 Epub 2012 Mar 23; Authors: Talos DM, Sun H, Kosaras B, Joseph A, Folkerth RD, Poduri A, Madsen JR, Black PM, Jensen FE

Contribution of axonal orientation to pathway-dependent modulation of excitatory transmission by direct current stimulation in isolated rat hippocampus.
Journal of neurophysiology. 2012 Apr;107(7):1881-9 Epub 2012 Jan 4; Authors: Kabakov AY, Muller PA, Pascual-Leone A, Jensen FE, Rotenberg A

Identification of new epilepsy treatments: issues in preclinical methodology.
Epilepsia. 2012 Mar;53(3):571-82 Epub 2012 Jan 31; Authors: Galanopoulou AS, Buckmaster PS, Staley KJ, Moshé SL, Perucca E, Engel J Jr, Löscher W, Noebels JL, Pitkänen A, Stables J, White HS, O'Brien TJ, Simonato M, American Epilepsy Society Basic Science Committee And The International League Against Epilepsy Working Group On Recommendations For Preclinical Epilepsy Drug Discovery

A new measure of cortical inhibition by mechanomyography and paired-pulse transcranial magnetic stimulation in unanesthetized rats.
Journal of neurophysiology. 2012 Feb;107(3):966-72 Epub 2011 Oct 19; Authors: Hsieh TH, Dhamne SC, Chen JJ, Pascual-Leone A, Jensen FE, Rotenberg A

The interaction between early life epilepsy and autistic-like behavioral consequences: a role for the mammalian target of rapamycin (mTOR) pathway.
PloS one. 2012;7(5):e35885 Epub 2012 May 2; Authors: Talos DM, Sun H, Zhou X, Fitzgerald EC, Jackson MC, Klein PM, Lan VJ, Joseph A, Jensen FE

Hypoxia-induced neonatal seizures diminish silent synapses and long-term potentiation in hippocampal CA1 neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 2011 Dec 14;31(50):18211-22; Authors: Zhou C, Lippman JJ, Sun H, Jensen FE

Regulable neural progenitor-specific Tsc1 loss yields giant cells with organellar dysfunction in a model of tuberous sclerosis complex.
Proceedings of the National Academy of Sciences of the United States of America. 2011 Nov 8;108(45):E1070-9 Epub 2011 Oct 24; Authors: Goto J, Talos DM, Klein P, Qin W, Chekaluk YI, Anderl S, Malinowska IA, Di Nardo A, Bronson RT, Chan JA, Vinters HV, Kernie SG, Jensen FE, Sahin M, Kwiatkowski DJ

The clinically available NMDA receptor antagonist, memantine, exhibits relative safety in the developing rat brain.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2011 Nov;29(7):767-73 Epub 2011 May 20; Authors: Manning SM, Boll G, Fitzgerald E, Selip DB, Volpe JJ, Jensen FE

Reprint of "The developing oligodendrocyte: key cellular target in brain injury in the premature infant".
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2011 Oct;29(6):565-82 Epub 2011 Jul 23; Authors: Volpe JJ, Kinney HC, Jensen FE, Rosenberg PA

Benign rolandic epileptiform discharges are associated with mood and behavior problems.
Epilepsy & behavior : E&B. 2011 Oct;22(2):298-303 Epub 2011 Aug 20; Authors: Sarco DP, Boyer K, Lundy-Krigbaum SM, Takeoka M, Jensen F, Gregas M, Waber DP

The developing oligodendrocyte: key cellular target in brain injury in the premature infant.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2011 Jun;29(4):423-40 Epub 2011 Mar 5; Authors: Volpe JJ, Kinney HC, Jensen FE, Rosenberg PA

Sensitive isotope dilution liquid chromatography/tandem mass spectrometry method for quantitative analysis of bumetanide in serum and brain tissue.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2011 Apr 15;879(13-14):998-1002 Epub 2011 Feb 19; Authors: Li Y, Cleary R, Kellogg M, Soul JS, Berry GT, Jensen FE

Development of later life spontaneous seizures in a rodent model of hypoxia-induced neonatal seizures.
Epilepsia. 2011 Apr;52(4):753-65 Epub 2011 Mar 2; Authors: Rakhade SN, Klein PM, Huynh T, Hilario-Gomez C, Kosaras B, Rotenberg A, Jensen FE

Measures of cortical inhibition by paired-pulse transcranial magnetic stimulation in anesthetized rats.
Journal of neurophysiology. 2011 Feb;105(2):615-24 Epub 2010 Dec 15; Authors: Vahabzadeh-Hagh AM, Muller PA, Pascual-Leone A, Jensen FE, Rotenberg A

Does acquired epileptogenesis in the immature brain require neuronal death.
Epilepsy currents. 2011 Jan;11(1):21-6; Authors: Baram TZ, Jensen FE, Brooks-Kayal A

Epilepsy as a spectrum disorder: Implications from novel clinical and basic neuroscience.
Epilepsia. 2011 Jan;52 Suppl 1:1-6; Authors: Jensen FE

Strain-specific differences in perinatal rodent oligodendrocyte lineage progression and its correlation with human.
Developmental neuroscience. 2011;33(3-4):251-60 Epub 2011 Aug 25; Authors: Dean JM, Moravec MD, Grafe M, Abend N, Ren J, Gong X, Volpe JJ, Jensen FE, Hohimer AR, Back SA

Developmental regulation of group I metabotropic glutamate receptors in the premature brain and their protective role in a rodent model of periventricular leukomalacia.
Neuron glia biology. 2010 Nov;6(4):277-88 Epub 2011 Dec 14; Authors: Jantzie LL, Talos DM, Selip DB, An L, Jackson MC, Folkerth RD, Deng W, Jensen FE

Lateralization of forelimb motor evoked potentials by transcranial magnetic stimulation in rats.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. 2010 Jan;121(1):104-8 Epub 2009 Nov 8; Authors: Rotenberg A, Muller PA, Vahabzadeh-Hagh AM, Navarro X, López-Vales R, Pascual-Leone A, Jensen F

Association of the small GTPase Rheb with the NMDA receptor subunit NR3A.
Neuro-Signals. 2010;18(4):203-9 Epub 2010 Dec 7; Authors: Sucher NJ, Yu E, Chan SF, Miri M, Lee BJ, Xiao B, Worley PF, Jensen FE

Altered development of glutamatergic synapses in layer V pyramidal neurons in NR3A knockout mice.
Molecular and cellular neurosciences. 2009 Dec;42(4):419-26 Epub 2009 Sep 24; Authors: Zhou C, Jensen FE, Sucher NJ

Neonatal seizures: an update on mechanisms and management.
Clinics in perinatology. 2009 Dec;36(4):881-900, vii; Authors: Jensen FE

Implications of the Emergency Medical Treatment and Labor Act (EMTALA) during public health emergencies and on alternate sites of care.
Disaster medicine and public health preparedness. 2009 Dec;3 Suppl 2:S172-5; Authors: Roszak AR, Jensen FR, Wild RE, Yeskey K, Handrigan MT

Introduction--epileptogenic cortical dysplasia: emerging trends in diagnosis, treatment, and pathogenesis.
Epilepsia. 2009 Oct;50 Suppl 9:1-2; Authors: Jensen FE

17beta-estradiol protects against hypoxic/ischemic white matter damage in the neonatal rat brain.
Journal of neuroscience research. 2009 Jul;87(9):2078-86; Authors: Gerstner B, Lee J, DeSilva TM, Jensen FE, Volpe JJ, Rosenberg PA

Epileptogenesis in the immature brain: emerging mechanisms.
Nature reviews. Neurology. 2009 Jul;5(7):380-91; Authors: Rakhade SN, Jensen FE

Talampanel suppresses the acute and chronic effects of seizures in a rodent neonatal seizure model.
Epilepsia. 2009 Apr;50(4):694-701 Epub 2009 Feb 12; Authors: Aujla PK, Fetell MR, Jensen FE

Curing epilepsy: progress and future directions.
Epilepsy & behavior : E&B. 2009 Mar;14(3):438-45; Authors: Jacobs MP, Leblanc GG, Brooks-Kayal A, Jensen FE, Lowenstein DH, Noebels JL, Spencer DD, Swann JW

Introduction. Posttraumatic epilepsy: treatable epileptogenesis.
Epilepsia. 2009 Feb;50 Suppl 2(Suppl 2):1-3; Authors: Jensen FE

Developmental factors in the pathogenesis of neonatal seizures.
Journal of pediatric neurology : JPN. 2009 Jan 1;7(1):5-12; Authors: Jensen FE

Seizure suppression by EEG-guided repetitive transcranial magnetic stimulation in the rat.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. 2008 Dec;119(12):2697-702 Epub 2008 Nov 1; Authors: Rotenberg A, Muller P, Birnbaum D, Harrington M, Riviello JJ, Pascual-Leone A, Jensen FE

Early alterations of AMPA receptors mediate synaptic potentiation induced by neonatal seizures.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 2008 Aug 6;28(32):7979-90; Authors: Rakhade SN, Zhou C, Aujla PK, Fishman R, Sucher NJ, Jensen FE

Improving the treatment of neonatal seizures: National Institute of Neurological Disorders and Stroke workshop report.
The Journal of pediatrics. 2008 Jul;153(1):12-5; Authors: Silverstein FS, Jensen FE, Inder T, Hellstrom-Westas L, Hirtz D, Ferriero DM

NMDA receptor blockade with memantine attenuates white matter injury in a rat model of periventricular leukomalacia.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 2008 Jun 25;28(26):6670-8; Authors: Manning SM, Talos DM, Zhou C, Selip DB, Park HK, Park CJ, Volpe JJ, Jensen FE

Cell-specific alterations of glutamate receptor expression in tuberous sclerosis complex cortical tubers.
Annals of neurology. 2008 Apr;63(4):454-65; Authors: Talos DM, Kwiatkowski DJ, Cordero K, Black PM, Jensen FE

Minimal heating of titanium skull plates during 1Hz repetitive transcranial magnetic stimulation.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. 2007 Nov;118(11):2536-8 Epub 2007 Sep 24; Authors: Rotenberg A, Harrington MG, Birnbaum DS, Madsen JR, Glass IE, Jensen FE, Pascual-Leone A

Neonatal seizures.
Annals of neurology. 2007 Aug;62(2):112-20; Authors: Silverstein FS, Jensen FE

A mouse model of tuberous sclerosis: neuronal loss of Tsc1 causes dysplastic and ectopic neurons, reduced myelination, seizure activity, and limited survival.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 2007 May 23;27(21):5546-58; Authors: Meikle L, Talos DM, Onda H, Pollizzi K, Rotenberg A, Sahin M, Jensen FE, Kwiatkowski DJ

Developmental factors regulating susceptibility to perinatal brain injury and seizures.
Current opinion in pediatrics. 2006 Dec;18(6):628-33; Authors: Jensen FE

Alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor subunit composition and cAMP-response element-binding protein regulate oligodendrocyte excitotoxicity.
The Journal of biological chemistry. 2006 Nov 24;281(47):36004-11 Epub 2006 Sep 21; Authors: Deng W, Neve RL, Rosenberg PA, Volpe JJ, Jensen FE

Randomized trial supports use of levetiracetam adjunctive therapy to treat partial seizures in children.
Nature clinical practice. Neurology. 2006 Nov;2(11):596-7; Authors: Jensen FE, Bourgeois BF

Oligodendrocyte excitotoxicity determined by local glutamate accumulation and mitochondrial function.
Journal of neurochemistry. 2006 Jul;98(1):213-22 Epub 2006 Apr 5; Authors: Deng W, Yue Q, Rosenberg PA, Volpe JJ, Jensen FE

Developmental regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor subunit expression in forebrain and relationship to regional susceptibility to hypoxic/ischemic injury. II. Human cerebral white matter and cortex.
The Journal of comparative neurology. 2006 Jul 1;497(1):61-77; Authors: Talos DM, Follett PL, Folkerth RD, Fishman RE, Trachtenberg FL, Volpe JJ, Jensen FE

Developmental regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor subunit expression in forebrain and relationship to regional susceptibility to hypoxic/ischemic injury. I. Rodent cerebral white matter and cortex.
The Journal of comparative neurology. 2006 Jul 1;497(1):42-60; Authors: Talos DM, Fishman RE, Park H, Folkerth RD, Follett PL, Volpe JJ, Jensen FE

Pediatric epilepsy models.
Epilepsy research. 2006 Jan;68(1):28-31; Authors: Jensen FE

Role of glutamate receptors in periventricular leukomalacia.
Journal of child neurology. 2005 Dec;20(12):950-9; Authors: Jensen FE

NKCC1 transporter facilitates seizures in the developing brain.
Nature medicine. 2005 Nov;11(11):1205-13 Epub 2005 Oct 9; Authors: Dzhala VI, Talos DM, Sdrulla DA, Brumback AC, Mathews GC, Benke TA, Delpire E, Jensen FE, Staley KJ

AMPA/kainate receptor-mediated downregulation of GABAergic synaptic transmission by calcineurin after seizures in the developing rat brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 2005 Mar 30;25(13):3442-51; Authors: Sanchez RM, Dai W, Levada RE, Lippman JJ, Jensen FE

12-Lipoxygenase plays a key role in cell death caused by glutathione depletion and arachidonic acid in rat oligodendrocytes.
The European journal of neuroscience. 2004 Oct;20(8):2049-58; Authors: Wang H, Li J, Follett PL, Zhang Y, Cotanche DA, Jensen FE, Volpe JJ, Rosenberg PA

NBQX or topiramate treatment after perinatal hypoxia-induced seizures prevents later increases in seizure-induced neuronal injury.
Epilepsia. 2004 Jun;45(6):569-75; Authors: Koh S, Tibayan FD, Simpson JN, Jensen FE

Role of metabotropic glutamate receptors in oligodendrocyte excitotoxicity and oxidative stress.
Proceedings of the National Academy of Sciences of the United States of America. 2004 May 18;101(20):7751-6 Epub 2004 May 10; Authors: Deng W, Wang H, Rosenberg PA, Volpe JJ, Jensen FE

Glutamate receptor-mediated oligodendrocyte toxicity in periventricular leukomalacia: a protective role for topiramate.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 2004 May 5;24(18):4412-20; Authors: Follett PL, Deng W, Dai W, Talos DM, Massillon LJ, Rosenberg PA, Volpe JJ, Jensen FE

Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway.
Proceedings of the National Academy of Sciences of the United States of America. 2003 Jul 8;100(14):8514-9 Epub 2003 Jun 24; Authors: Lehnardt S, Massillon L, Follett P, Jensen FE, Ratan R, Rosenberg PA, Volpe JJ, Vartanian T

Calcium-permeable AMPA/kainate receptors mediate toxicity and preconditioning by oxygen-glucose deprivation in oligodendrocyte precursors.
Proceedings of the National Academy of Sciences of the United States of America. 2003 May 27;100(11):6801-6 Epub 2003 May 12; Authors: Deng W, Rosenberg PA, Volpe JJ, Jensen FE

Mature myelin basic protein-expressing oligodendrocytes are insensitive to kainate toxicity.
Journal of neuroscience research. 2003 Jan 15;71(2):237-45; Authors: Rosenberg PA, Dai W, Gan XD, Ali S, Fu J, Back SA, Sanchez RM, Segal MM, Follett PL, Jensen FE, Volpe JJ

The role of glutamate receptor maturation in perinatal seizures and brain injury.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2002 Jun-Aug;20(3-5):339-47; Authors: Jensen FE

The toll-like receptor TLR4 is necessary for lipopolysaccharide-induced oligodendrocyte injury in the CNS.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 2002 Apr 1;22(7):2478-86; Authors: Lehnardt S, Lachance C, Patrizi S, Lefebvre S, Follett PL, Jensen FE, Rosenberg PA, Volpe JJ, Vartanian T

Relationship between encephalopathy and abnormal neuronal activity in the developing brain.
International review of neurobiology. 2002;49:23-35; Authors: Jensen FE