Sudha K. Kessler Publications

Comparative molecular landscapes of immature neurons in the mammalian dentate gyrus across species reveal special features in humans.
bioRxiv : the preprint server for biology. 2025 Feb 17; Authors: Zhou Y, Su Y, Yang Q, Li J, Hong Y, Gao T, Zhong Y, Ma X, Jin M, Liu X, Yuan N, Kennedy BC, Wang L, Yan L, Viaene AN, Helbig I, Kessler SK, Kleinman JE, Hyde TM, Nauen DW, Liu C, Liu Z, Shen Z, Li C, Xu S, He J, Weinberger DR, Ming GL, Song H
Epilepsy Genetics.
Continuum (Minneapolis, Minn.). 2025 Feb 1;31(1):81-94; Authors: Kessler SK
Brain-wide neuronal circuit connectome of human glioblastoma.
Nature. 2025 Jan 16; Authors: Sun Y, Wang X, Zhang DY, Zhang Z, Bhattarai JP, Wang Y, Park KH, Dong W, Hung YF, Yang Q, Zhang F, Rajamani K, Mu S, Kennedy BC, Hong Y, Galanaugh J, Sambangi A, Kim SH, Wheeler G, Gonçalves T, Wang Q, Geschwind DH, Kawaguchi R, Viaene AN, Helbig I, Kessler SK, Hoke A, Wang H, Xu F, Binder ZA, Isaac Chen H, Pai EL, Stone S, Nasrallah MP, Christian KM, Fuccillo M, Toni N, Wu Z, Cheng HJ, O'Rourke DM, Ma M, Ming GL, Song H
Diagnostic Yield of CSF Testing in Infants for Disorders of Biogenic Amine Neurotransmitter Metabolism.
Neurology. 2024 May;102(9):e209300 Epub 2024 Apr 17; Authors: Kessler R, Fung FW, Patel A, Gupta N, McHugh T, Gonzalez AK, Rodan L, Harini C, Kessler SK
Periodic Discharges in Critically Ill Children: Predictors and Outcome.
Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society. 2024 May 1;41(4):297-304 Epub 2023 Dec 1; Authors: Fung FW, Parikh DS, Massey SL, Fitzgerald MP, Vala L, Donnelly M, Jacobwitz M, Kessler SK, Xiao R, Topjian AA, Abend NS
Education Research: Quality and Validity Evidence for a National In-Training Examination for Epilepsy Fellows.
Neurology. Education. 2023 Dec 22;2(4):e200090 Epub 2023 Oct 26; Authors: Moeller J, Gonzalez-Giraldo E, Fung FW, Johnson EL, Kheder A, MacLean J, McGinnis EL, Muhlhofer WG, Oster JM, Schmitt S, Voinescu PE, Wong-Kisiel LC, Kidd KJ, Kephart A, Lado FA, Kessler SK
A quality improvement initiative to improve folic acid supplementation counseling for adolescent females with epilepsy.
Epilepsia. 2023 Oct;64(10):2818-2826 Epub 2023 Aug 4; Authors: Molisani SE, Parikh D, DiGiovine M, Dlugos D, Fitzgerald MP, Fried L, Helbig I, Kessler SK, McDonnell PP, Melamed S, Prelack MS, Sharif U, Tefft S, Tencer J, Witzman S, Shaw K, Abend NS
Leveraging electronic medical record-embedded standardised electroencephalogram reporting to develop neonatal seizure prediction models: a retrospective cohort study.
The Lancet. Digital health. 2023 Apr;5(4):e217-e226; Authors: McKee JL, Kaufman MC, Gonzalez AK, Fitzgerald MP, Massey SL, Fung F, Kessler SK, Witzman S, Abend NS, Helbig I
A single-cell transcriptome atlas of glial diversity in the human hippocampus across the postnatal lifespan.
Cell stem cell. 2023 Jan 5;30(1):113; Authors: Su Y, Zhou Y, Bennett ML, Li S, Carceles-Cordon M, Lu L, Huh S, Jimenez-Cyrus D, Kennedy BC, Kessler SK, Viaene AN, Helbig I, Gu X, Kleinman JE, Hyde TM, Weinberger DR, Nauen DW, Song H, Ming GL
Surgical Treatments for Epilepsies in Children Aged 1-36 Months: A Systematic Review.
Neurology. 2023 Jan 3;100(1):e1-e15 Epub 2022 Oct 21; Authors: Tsou AY, Kessler SK, Wu M, Abend NS, Massey SL, Treadwell JR
Pharmacologic and Dietary Treatments for Epilepsies in Children Aged 1-36 Months: A Systematic Review.
Neurology. 2023 Jan 3;100(1):e16-e27 Epub 2022 Oct 21; Authors: Treadwell JR, Kessler SK, Wu M, Abend NS, Massey SL, Tsou AY
A single-cell transcriptome atlas of glial diversity in the human hippocampus across the postnatal lifespan.
Cell stem cell. 2022 Nov 3;29(11):1594-1610.e8; Authors: Su Y, Zhou Y, Bennett ML, Li S, Carceles-Cordon M, Lu L, Huh S, Jimenez-Cyrus D, Kennedy BC, Kessler SK, Viaene AN, Helbig I, Gu X, Kleinman JE, Hyde TM, Weinberger DR, Nauen DW, Song H, Ming GL
Walking speed influences spatiotemporal but not symmetry measures of gait in children and adolescents with hemiplegia.
Gait & posture. 2022 Oct;98:233-236 Epub 2022 Sep 29; Authors: Prosser LA, Atkinson HL, Alfano JM, Kessler SK, Ichord RB
Stereoelectroencephalography before 2 years of age.
Neurosurgical focus. 2022 Oct;53(4):E3; Authors: Rahman RK, Tomlinson SB, Katz J, Galligan K, Madsen PJ, Tucker AM, Kessler SK, Kennedy BC
Normalizing step-to-step variability to age in children and adolescents with hemiplegia.
Gait & posture. 2022 Oct;98:6-8 Epub 2022 Aug 18; Authors: Prosser LA, Atkinson HL, Alfano JM, Leff M, Kessler SK, Gouelle A, Ichord RB
Clinical Characteristics of Seizures and Epilepsy in Individuals With Recurrent Deletions and Duplications in the 16p11.2 Region.
Neurology. Genetics. 2022 Oct;8(5):e200018 Epub 2022 Aug 5; Authors: Moufawad El Achkar C, Rosen A, Kessler SK, Steinman KJ, Spence SJ, Ramocki M, Marco EJ, Green Snyder L, Spiro JE, Chung WK, Annapurna P, Sherr EH
Molecular landscapes of human hippocampal immature neurons across lifespan.
Nature. 2022 Jul;607(7919):527-533 Epub 2022 Jul 6; Authors: Zhou Y, Su Y, Li S, Kennedy BC, Zhang DY, Bond AM, Sun Y, Jacob F, Lu L, Hu P, Viaene AN, Helbig I, Kessler SK, Lucas T, Salinas RD, Gu X, Chen HI, Wu H, Kleinman JE, Hyde TM, Nauen DW, Weinberger DR, Ming GL, Song H
Proposal for an updated seizure classification framework in clinical trials.
Epilepsia. 2022 Mar;63(3):565-572 Epub 2022 Jan 7; Authors: Steriade C, Sperling MR, DiVentura B, Lozano M, Shellhaas RA, Kessler SK, Dlugos D, French J
5-Year Activity and Participation Outcomes of the First Successful Pediatric Bilateral Hand Transplantation: A Case Report.
Physical & occupational therapy in pediatrics. 2022;42(6):663-679 Epub 2022 Apr 4; Authors: Levy TJ, Tyner CE, Amaral S, Lefkowitz DS, Kessler SK, Levin LS
Periodic and rhythmic patterns in critically ill children: Incidence, interrater agreement, and seizures.
Epilepsia. 2021 Dec;62(12):2955-2967 Epub 2021 Oct 12; Authors: Fung FW, Parikh DS, Massey SL, Fitzgerald MP, Vala L, Donnelly M, Jacobwitz M, Kessler SK, Topjian AA, Abend NS
Assessing seizure burden in pediatric epilepsy using an electronic medical record-based tool through a common data element approach.
Epilepsia. 2021 Jul;62(7):1617-1628 Epub 2021 Jun 2; Authors: Fitzgerald MP, Kaufman MC, Massey SL, Fridinger S, Prelack M, Ellis C, Ortiz-Gonzalez X, Fried LE, DiGiovine MP, CHOP Pediatric Epilepsy Program Collaborative, Melamed S, Malcolm M, Banwell B, Stephenson D, Witzman SM, Gonzalez A, Dlugos D, Kessler SK, Goldberg EM, Abend NS, Helbig I
Analyzing 2,589 child neurology telehealth encounters necessitated by the COVID-19 pandemic.
Neurology. 2020 Sep 1;95(9):e1257-e1266 Epub 2020 Jun 9; Authors: Rametta SC, Fridinger SE, Gonzalez AK, Xian J, Galer PD, Kaufman M, Prelack MS, Sharif U, Fitzgerald MP, Melamed SE, Malcolm MP, Kessler SK, Stephenson DJ, Banwell BL, Abend NS, Helbig I
Unplanned Readmissions of Children With Epilepsy in the United States.
Pediatric neurology. 2020 Jul;108:93-98 Epub 2020 Feb 7; Authors: Kessler SK, Blank LJ, Glusman J, Thibault D, Massey S, Abend NS, Szperka CL, Crispo JAG, Willis AW
Differential antiseizure medication sensitivity of the Affective Reactivity Index: A randomized controlled trial in new-onset pediatric focal epilepsy.
Epilepsy & behavior : E&B. 2020 Jan;102:106687 Epub 2019 Dec 6; Authors: Loring DW, Meador KJ, Shinnar S, Gaillard WD, Wheless JW, Kessler SK, Conry JA, Berl MM, Burns TG, Glauser TA, Kinkead B, Cnaan A
A Practical Guide to Treatment of Childhood Absence Epilepsy.
Paediatric drugs. 2019 Feb;21(1):15-24; Authors: Kessler SK, McGinnis E
High electroencephalographic seizure exposure is associated with unfavorable outcomes in neonates with hypoxic-ischemic encephalopathy.
Seizure. 2018 Oct;61:221-226 Epub 2018 Sep 11; Authors: Fitzgerald MP, Massey SL, Fung FW, Kessler SK, Abend NS
Magnifying the View of the Hand Changes Its Cortical Representation. A Transcranial Magnetic Stimulation Study.
Journal of cognitive neuroscience. 2018 Aug;30(8):1098-1107 Epub 2018 Apr 18; Authors: Ambron E, White N, Faseyitan O, Kessler SK, Medina J, Coslett HB
Stability of Early EEG Background Patterns After Pediatric Cardiac Arrest.
Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society. 2018 May;35(3):246-250; Authors: Abend NS, Xiao R, Kessler SK, Topjian AA
Homozygous boricua TBCK mutation causes neurodegeneration and aberrant autophagy.
Annals of neurology. 2018 Jan;83(1):153-165; Authors: Ortiz-González XR, Tintos-Hernández JA, Keller K, Li X, Foley AR, Bharucha-Goebel DX, Kessler SK, Yum SW, Crino PB, He M, Wallace DC, Bönnemann CG
Massive cortical reorganization is reversible following bilateral transplants of the hands: evidence from the first successful bilateral pediatric hand transplant patient.
Annals of clinical and translational neurology. 2018 Jan;5(1):92-97 Epub 2017 Dec 6; Authors: Gaetz W, Kessler SK, Roberts TPL, Berman JI, Levy TJ, Hsia M, Humpl D, Schwartz ES, Amaral S, Chang B, Levin LS
The second report of bilateral hand transplantation in a child - Author reply.
The Lancet. Child & adolescent health. 2017 Dec;1(4):e3 Epub 2017 Nov 15; Authors: Amaral S, Kessler SK
18-month outcomes of heterologous bilateral hand transplantation in a child: a case report.
The Lancet. Child & adolescent health. 2017 Sep;1(1):35-44 Epub 2017 Jul 18; Authors: Amaral S, Kessler SK, Levy TJ, Gaetz W, McAndrew C, Chang B, Lopez S, Braham E, Humpl D, Hsia M, Ferry KA, Xu X, Elder D, Lefkowitz D, Feudtner C, Thibaudeau S, Lin IC, Kovach SJ, Schwartz ES, Bozentka D, Carrigan R, Steinberg D, Kanchwala S, Zlotolow DA, Kozin S, Jensen FE, Bryant PR, Shaked A, Levine MH, Levin LS
Pretreatment seizure semiology in childhood absence epilepsy.
Neurology. 2017 Aug 15;89(7):673-679 Epub 2017 Jul 19; Authors: Kessler SK, Shinnar S, Cnaan A, Dlugos D, Conry J, Hirtz DG, Hu F, Liu C, Mizrahi EM, Moshé SL, Clark P, Glauser TA, Childhood Absence Epilepsy Study Group
Neuromagnetic responses to tactile stimulation of the fingers: Evidence for reduced cortical inhibition for children with Autism Spectrum Disorder and children with epilepsy.
NeuroImage. Clinical. 2017;16:624-633 Epub 2017 Jun 23; Authors: Gaetz W, Jurkiewicz MT, Kessler SK, Blaskey L, Schwartz ES, Roberts TPL
Early discontinuation of antiseizure medications in neonates with hypoxic-ischemic encephalopathy.
Epilepsia. 2017 Jun;58(6):1047-1053 Epub 2017 Apr 12; Authors: Fitzgerald MP, Kessler SK, Abend NS
Incidence of Recurrence in Posterior Circulation Childhood Arterial Ischemic Stroke.
JAMA neurology. 2017 Mar 1;74(3):316-323; Authors: Uohara MY, Beslow LA, Billinghurst L, Jones BM, Kessler SK, Licht DJ, Ichord RN
16p11.2 deletion and duplication: Characterizing neurologic phenotypes in a large clinically ascertained cohort.
American journal of medical genetics. Part A. 2016 Nov;170(11):2943-2955 Epub 2016 Jul 13; Authors: Steinman KJ, Spence SJ, Ramocki MB, Proud MB, Kessler SK, Marco EJ, Green Snyder L, D'Angelo D, Chen Q, Chung WK, Sherr EH, Simons VIP Consortium
Lacosamide use in children with epilepsy: Retention rate and effect of concomitant sodium channel blockers in a large cohort.
Epilepsia. 2016 Sep;57(9):1416-25 Epub 2016 Jul 19; Authors: McGinnis E, Kessler SK
Impact of an ICU EEG monitoring pathway on timeliness of therapeutic intervention and electrographic seizure termination.
Epilepsia. 2016 May;57(5):786-95 Epub 2016 Mar 7; Authors: Williams RP, Banwell B, Berg RA, Dlugos DJ, Donnelly M, Ichord R, Kessler SK, Lavelle J, Massey SL, Hewlett J, Parker A, Topjian AA, Abend NS
Retention rates of rufinamide in pediatric epilepsy patients with and without Lennox-Gastaut Syndrome.
Epilepsy research. 2015 May;112:18-26 Epub 2015 Feb 14; Authors: Kessler SK, McCarthy A, Cnaan A, Dlugos DJ
Risk of seizure recurrence after achieving initial seizure freedom on the ketogenic diet.
Epilepsia. 2014 Apr;55(4):579-83 Epub 2014 Mar 27; Authors: Taub KS, Kessler SK, Bergqvist AG
Dosage considerations for transcranial direct current stimulation in children: a computational modeling study.
PloS one. 2013;8(9):e76112 Epub 2013 Sep 27; Authors: Kessler SK, Minhas P, Woods AJ, Rosen A, Gorman C, Bikson M
Density spectral array for seizure identification in critically ill children.
Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society. 2013 Aug;30(4):371-5; Authors: Pensirikul AD, Beslow LA, Kessler SK, Sanchez SM, Topjian AA, Dlugos DJ, Abend NS
Headache as a risk factor for neurovascular events in pediatric brain tumor patients.
Neurology. 2013 Apr 16;80(16):1452-6 Epub 2013 Mar 13; Authors: Kranick SM, Campen CJ, Kasner SE, Kessler SK, Zimmerman RA, Lustig RA, Phillips PC, Beslow LA, Ichord R, Fisher MJ
Pediatric ICU EEG monitoring: current resources and practice in the United States and Canada.
Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society. 2013 Apr;30(2):156-60; Authors: Sanchez SM, Carpenter J, Chapman KE, Dlugos DJ, Gallentine WB, Giza CC, Goldstein JL, Hahn CD, Kessler SK, Loddenkemper T, Riviello JJ Jr, Abend NS, Pediatric Critical Care EEG Group
Cranial irradiation increases risk of stroke in pediatric brain tumor survivors.
Stroke. 2012 Nov;43(11):3035-40 Epub 2012 Sep 11; Authors: Campen CJ, Kranick SM, Kasner SE, Kessler SK, Zimmerman RA, Lustig R, Phillips PC, Storm PB, Smith SE, Ichord R, Fisher MJ
Modified Pediatric ASPECTS Correlates with Infarct Volume in Childhood Arterial Ischemic Stroke.
Frontiers in neurology. 2012;3:122 Epub 2012 Jul 31; Authors: Beslow LA, Vossough A, Dahmoush HM, Kessler SK, Stainman R, Favilla CG, Wusthoff CJ, Zelonis S, Licht DJ, Ichord RN, Smith SE
Differences in the experience of active and sham transcranial direct current stimulation.
Brain stimulation. 2012 Apr;5(2):155-62 Epub 2011 Mar 27; Authors: Kessler SK, Turkeltaub PE, Benson JG, Hamilton RH
Outcome prediction by motor and pupillary responses in children treated with therapeutic hypothermia after cardiac arrest.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 2012 Jan;13(1):32-8; Authors: Abend NS, Topjian AA, Kessler SK, Gutierrez-Colina AM, Berg RA, Nadkarni V, Dlugos DJ, Clancy RR, Ichord RN
Transcranial direct current stimulation in pediatric brain: a computational modeling study.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2012;2012:859-62; Authors: Minhas P, Bikson M, Woods AJ, Rosen AR, Kessler SK
Stimulus-induced rhythmic, periodic, or ictal discharges in a 13-year-old girl after an overdose and respiratory arrest.
Pediatric neurology. 2011 Nov;45(5):350-1; Authors: Skjei KL, Kessler SK, Abend NS
Anti-NMDA receptor encephalitis presenting with focal non-convulsive status epilepticus in a child.
Neuropediatrics. 2011 Oct;42(5):188-90 Epub 2011 Nov 22; Authors: Goldberg EM, Taub KS, Kessler SK, Abend NS
Seizures as a presenting symptom of acute arterial ischemic stroke in childhood.
The Journal of pediatrics. 2011 Sep;159(3):479-83 Epub 2011 Mar 22; Authors: Abend NS, Beslow LA, Smith SE, Kessler SK, Vossough A, Mason S, Agner S, Licht DJ, Ichord RN
Dietary therapies for epilepsy: future research.
Epilepsy & behavior : E&B. 2011 Sep;22(1):17-22 Epub 2011 Mar 26; Authors: Kessler SK, Neal EG, Camfield CS, Kossoff EH
Risk of later seizure after perinatal arterial ischemic stroke: a prospective cohort study.
Pediatrics. 2011 Jun;127(6):e1550-7 Epub 2011 May 16; Authors: Wusthoff CJ, Kessler SK, Vossough A, Ichord R, Zelonis S, Halperin A, Gordon D, Vargas G, Licht DJ, Smith SE
Early EEG improvement after ketogenic diet initiation.
Epilepsy research. 2011 Mar;94(1-2):94-101 Epub 2011 Feb 23; Authors: Kessler SK, Gallagher PR, Shellhaas RA, Clancy RR, Bergqvist AG
Short-term outcome prediction by electroencephalographic features in children treated with therapeutic hypothermia after cardiac arrest.
Neurocritical care. 2011 Feb;14(1):37-43; Authors: Kessler SK, Topjian AA, Gutierrez-Colina AM, Ichord RN, Donnelly M, Nadkarni VM, Berg RA, Dlugos DJ, Clancy RR, Abend NS