What is Neuromodulation?

Forrest Lin, undergraduate researcher in our lab, performing TMS on LCNS director, Olu Faseyitan, while mentor Kelly Sloane reviews MRI scans to optimize coil placement.
Forrest Lin, undergraduate researcher in our lab, performing TMS on LCNS director, Olu Faseyitan, while mentor Kelly Sloane reviews MRI scans to optimize coil placement.

A major focus of our laboratory is to understand and optimize brain injury recovery using neuromodulatory techniques. Neuromodulation refers to techniques that change the activity of the brain using gentle electrical or magnetic stimulation. Two common non-invasive forms are:

  • tDCS (transcranial direct current stimulation): sends a small electrical current through the scalp to make certain brain areas slightly more or less active.

  • TMS (transcranial magnetic stimulation): uses magnetic pulses to activate or inhibit specific parts of the brain.

After a stroke, the brain must reorganize itself to regain lost functions like movement, speech, and attention. This process is called neuroplasticity—the brain’s ability to form new connections. Neuromodulation can be used for diagnostic and treatment purposes. For diagnosis, it can temporarily modify brain activity, helping scientists map how different networks support recovery. For treatment, It can stimulate damaged or under-active brain areas to enhance functional abilities. By enhancing neuroplasticity, it can provide insights into why some therapies work better for certain patients.

Learn more about TMS and tDCS.