Our Mission

One Penn Medicine. One Research, drives integrated, innovative research across the Penn Medicine Health System, providing technology advancements and care for our patients and community.

If you are a health care provider in search of Penn Medicine clinical trials that are enrolling patients please view our clinical research opportunities.

For physicians seeking support for Expanded Access Protocols please contact OCR Regulatory.

The central hub for clinical research is the Office of Clinical Research, whose goal is to foster collaborative and innovative research that pursues new ways to care for our patients, accelerates patients’ access to experimental therapy and provides Penn Medicine physicians opportunities to engage in our research mission.

Meet the Office of Clinical Research

Featured Highlights

Emma Meagher Speaks at FDA: Agency Turns to AI to Speed Up Clinical Trials

The FDA recently announced a revolutionary pilot program to review clinical trial data in real-time. By utilizing cloud-based platforms and AI, regulators can now see safety signals and clinical endpoints as they happen—rather than waiting months for data transfers. At Penn Medicine, we are proud to be at the forefront of this shift. Emma A. Meagher, M.D., senior vice dean for clinical and translational research, joined the FDA's press conference to share why this is such a pivotal moment for the field.

Four Penn studies named among nation’s top clinical research advances

Perelman School of Medicine papers win Clinical Research Forum’s 2026 Top 10 Clinical Research Achievement Awards, highlighting the power of federal funding for science.

Where science meets compassion — and teams turn hope into healing.

CAR-T therapy has transformed cancer treatment — but its potential stretches far beyond oncology. In this special edition of CureTalk, we step beyond the headlines and shine a light on the remarkable people — the Penn scientists, nurses, engineers, clinicians, and patient advocates — who work tirelessly to advance CAR-T therapies for a broader range of diseases. Join us as we explore the human spirit driving this scientific revolution, and hear how collaboration, creativity, and care are shaping the future of medicine.

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Pioneering strategy may keep breast cancer from coming back

A clinical trial led by scientists from the Abramson Cancer Center and the Perelman School of Medicine offers proof-of-concept for a treatment approach to prevent breast cancer recurrence.

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Penn Medicine- Clinical Research