Dirk Trauner

Dirk Trauner

Professor

4001 Vagelos Laboratory, 231 S. 34th St.

Lab Website

Research Description

The broad objective of Prof. Trauner’s research is to demonstrate the awesome power of chemical synthesis and to use it toward the precision control of biological pathways, especially in neuroscience.  He is a pioneer in Chemical Optogenetics, Photopharmacology, and Synthetic Physiology, and has made significant contribution to the biosynthetic elucidation and chemical synthesis of complex, bioactive natural products.

Publications

Omo-Lamai S, Wang Y, Patel MN, Milosavljevic A, Zuschlag D, Poddar S, Wu J, Wang L, Dong F, Espy C, Majumder A, Essien EO, Shen M, Channer B, Papp TE, Tobin M, Maheshwari R, Jeong S, Patel S, Shah A, Murali S, Chase LS, Zamora ME, Arral ML, Marcos-Contreras OA, Myerson JW, Hunter CA, Discher D, Gaskill PJ, Tsourkas A, Muzykantov VR, Brodsky I, Shin S, Whitehead KA, Parhiz H, Katzen J, Miner JJ, Trauner D, Brenner JS. - Nat Nanotechnol. 2025 Aug 11. doi: 10.1038/s41565-025-01974-5. Epub ahead of print. PMID: 40789922.
Wilharm RK, Gau MR, Trauner D, Schelter EJ J Am Chem Soc. 2025 Aug 6;147(31):27143-27147. doi: 10.1021/jacs.5c05257. Epub 2025 Jul 24. PMID: 40705825.
Hetzler BE, Donthamsetti P, Wolesensky RM, Stanley C, Isacoff EY, Trauner D. - bioRxiv [Preprint]. 2025 Jun 15:2025.06.10.658926. doi: 10.1101/2025.06.10.658926. PMID: 40661587; PMCID: PMC12259131.
Ko T, Jou C, Grau-Perales AB, Reynders M, Fenton AA, Trauner D. - DOI: 10.1021/acschemneuro.3c00390
Hetzler BE, Donthamsetti P, Peitsinis Z, Stanley C, Trauner D, Isacoff EY. J Am Chem Soc. 2023 Aug 30;145(34):18778-18788. doi: 10.1021/jacs.3c02735. Epub 2023 Aug 16. PMID: 37586061.