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Friend of GATA2 Variant Ser657Gly Is Associated With Coronary Microvascular Disease

Guerraty MA, Verma SS, Ko YA, McQuillan MA, Conlon D, Tobias JW, Levin MG, Haury W, Zheng F, Cherlin T, Zhang C, Judy R, Tishkoff SA, Damrauer SM, Arany Z, Rader DJ. Friend of GATA2 Variant Ser657Gly Is Associated With Coronary Microvascular Disease. Circ Genom Precis Med. 2026 Apr 1:e005342. doi: 10.1161/CIRCGEN.125.005342. Epub ahead of print. PMID: 41919390.

Non-muscle tropomyosins inhibit Myosin-19 and dynamically localize to mitochondrially-associated actin filaments

Thompson CP, Pollard LW, Xu M, Holzbaur ELF, Ostap EM. Non-muscle tropomyosins inhibit Myosin-19 and dynamically localize to mitochondrially-associated actin filaments. J Biol Chem. 2026 Mar 17:111377. doi: 10.1016/j.jbc.2026.111377. Epub ahead of print. PMID: 41856285.

Unbiased cleavage site prediction uncovers viral antagonism of host innate immunity by SARS-CoV-2 3C-like protease

Yucel N, Marchiano S, Tchelepi E, Paterlini G, Kuznetsov IA, Li K, McAfee Q, Nimmagadda N, Ren A, Shi S, Grogan A, Kontrogianni-Konstantopoulos A, Murry C, Arany Z. Unbiased cleavage site prediction uncovers viral antagonism of host innate immunity by SARS-CoV-2 3C-like protease. JCI Insight. 2026 Feb 23;11(4):e185739. doi: 10.1172/jci.insight.185739. PMID: 41729072; PMCID: PMC12956004.

Role of nuclear ATPases in nuclear mechanics and cell migration through confined spaces: Opposite effects of BRG1 and cohesin

Suprewicz Ł, Byfield FJ, Dutta TT, Janmey PA. Role of nuclear ATPases in nuclear mechanics and cell migration through confined spaces: Opposite effects of BRG1 and cohesin. Biophys J. 2026 Feb 14:S0006-3495(26)00113-X. doi: 10.1016/j.bpj.2026.02.011. Epub ahead of print. PMID: 41691374; PMCID: PMC13036816.

Mechanism of Arp2/3 complex branch disassembly by human Coro7

Shatery Nejad N, Boczkowska M, Hilal R, Fregoso FE, Barrie KR, Rebowski G, Saks AJ, Gautreau AM, De La Cruz EM, Dominguez R. Mechanism of Arp2/3 complex branch disassembly by human Coro7. Nat Commun. 2025 Nov 6;16(1):9809. doi: 10.1038/s41467-025-64787-z. PMID: 41198690; PMCID: PMC12592476.

Limiting endosomal damage sensing reduces inflammation triggered by lipid nanoparticle endosomal escape. Nat Nanotechnol

Omo-Lamai S, Wang Y, Patel MN, Milosavljevic A, Zuschlag D, Poddar S, Wu J, Wang L, Dong F, Espy C, Majumder A, Essien EO, Shen M, Channer B, Papp TE, Tobin M, Maheshwari R, Jeong S, Patel S, Shah A, Murali S, Chase LS, Zamora ME, Arral ML, Marcos-Contreras OA, Myerson JW, Hunter CA, Discher D, Gaskill PJ, Tsourkas A, Muzykantov VR, Brodsky I, Shin S, Whitehead KA, Parhiz H, Katzen J, Miner JJ, Trauner D, Brenner JS. – Nat Nanotechnol. 2025 Aug 11. doi: 10.1038/s41565-025-01974-5. Epub ahead of print. PMID: 40789922.

Mitochondrial damage triggers the concerted degradation of negative regulators of neuronal autophagy

Bishal Basak, Erika L F Holzbaur PMID: 40783388 PMCID: PMC12335601 DOI: 10.1038/s41467-025-62379-5

Mechanical regulation of extracellular vesicle activity during tumour progression

Kshitiz Parihar, Di-Ao Liu, Ghmkin Hassan, David A Issadore, Paul A Janmey, Valerie M Weaver, Wei Guo, Ravi Radhakrishnan – PMID: 40770502 PMCID: PMC12337232 (available on 2026-08-06) DOI: 10.1038/s41551-025-01446-0

Breaking a Lewis Acidity Trend for Rare Earths by Excited State Quenching

Wilharm RK, Gau MR, Trauner D, Schelter EJ J Am Chem Soc. 2025 Aug 6;147(31):27143-27147. doi: 10.1021/jacs.5c05257. Epub 2025 Jul 24. PMID: 40705825.

What do we know of human fuel use during aerobic exercise and how do we know it?

Jessie Axsom, Zolt Arany – PMID: 40763088 DOI:10.1152/physiol.00002.2025

Right Ventricular Dysfunction and Adverse Clinical Outcomes in Peripartum Cardiomyopathy: A Meta-Analysis

Ali A Khan, Fayez H Fayad, Chan W Kim, Feven Ataklte, Phinnara Has, Ali Nebipasagil, Zolt Arany, Athena Poppas, Wen-Chih Wu, Gaurav Choudhary, Tasnim F Imran – PMID: 40768944 DOI: 10.1016/j.jacadv.2025.102047

Reprogramming of endolysosomes for melanogenesis in BLOC-1-deficient melanocytes

Philip S Goff, Shyamal Patel, Dawn C Harper, Tom Carter, Michael S Marks, Elena V Sviderskaya – PMID: 40683250 PMCID: PMC12320751 (available on 2026-07-18) DOI: 10.1016/j.cub.2025.06.031

A myosin hypertrophic cardiomyopathy mutation disrupts the super-relaxed state and boosts contractility by enhanced actin attachment

Robert C Cail, Bipasha Barua, Faviolla A Báez-Cruz, Donald A Winkelmann, Yale E Goldman, E Michael Ostap – PMID: 40501550 PMCID: PMC12157379 DOI: 10.1101/2025.06.02.657466

Matrix Stiffening Induces Mechanical Memory and Nuclear Fragility in Cardiomyocytes via Microtubule-Lamin Coupling

Nesrine Bouhrira, Sebastian Pizarro, Victor Senf, Kenneth B Margulies – PMID: 40777352 PMCID: PMC12330650 DOI: 10.1101/2025.07.17.665449

Acidic Nanoparticles Prevent HIV Pre-Exposure Prophylaxis (PrEP)-Induced Oligodendrocyte Impairments by Restoring Lysosomal pH in Adolescent Models

Caela C Long, Lindsay K Festa, Melanie Cruz-Berrios, Teshawn D Johnson, Claire H Mitchell, Kelly L Jordan-Sciutto, Judith B Grinspan – PMID: 40676765 PMCID: PMC12334864 DOI: 10.1002/glia.70050

AAV-microutrophin gene therapy confers durable cardioprotection against pharmacologic and exercise-induced injury in the mdx mouse

Coral M Kasden, Maria P Corzo, Christopher D Greer, Tanvi Singh, Rufranshell Reyes, Alaine Castillo, Zoltan Arany, Benjamin W Kozyak, Hansell H Stedman – PMID: 40671677 DOI: 10.1016/j.ymthe.2025.07.013

Autophagic stress activates distinct compensatory secretory pathways in neurons

Sierra D Palumbos, Jacob Popolow, Juliet Goldsmith, Erika L F Holzbaur PMID: 40623183 PMCID: PMC12280970 DOI: 10.1073/pnas.2421886122

Structural-functional characterization of the MIRO1-TRAK1 complex

Erika E Ravitch, Elana E Baltrusaitis, Tania A Perez, Kyle R Barrie, Adam R Fenton, Erika L F Holzbaur, Roberto Dominguez – PMID: 40615373 PMCID: PMC12227652 DOI: 10.1038/s41467-025-61174-6

Amino acid-level differences in alpha-tubulin sequences are uniquely required for meiosis

Li Chen, Xi Chen, Anna Kashina – PMID: 40434897 PMCID: PMC12260170 (available on 2026-07-01) DOI: 10.1091/mbc.E24-11-0529

Selective Vulnerability of Cancer Cells by Inhibition of Ca2+ Transfer from Endoplasmic Reticulum to Mitochondria

César Cárdenas, Marioly Müller, Andrew McNeal, Alenka Lovy, Fabian Jaňa, Galdo Bustos, Felix Urra, Natalia Smith, Jordi Molgó, J Alan Diehl, Todd W Ridky, J Kevin Foskett – PMID: 40478732 PMCID: PMC12239728 DOI: 10.1016/j.celrep.2025.115869