People
Principal Investigator
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Read More about Daniel J. Rader, MD
Daniel J. Rader, MD
Seymour Gray Professor of Molecular Medicine
rader@pennmedicine.upenn.edu
Dr. Rader is a physician-scientist with a long and meritorious history as researcher. His career has focused on the use of human genetics for identification of novel pathways involved in metabolic and cardiovascular phenotypes and diseases, and studies in both model systems and humans with the goal of elucidating molecular and physiological mechanisms. He has also pursued the implications of his work for translational therapeutics and precision medicine. He has long been engaged in human genetics discovery of both Mendelian lipid disorders and complex traits. In that context he has led projects involving genotype-directed deep phenotyping of individuals with Mendelian conditions or rare mutations, as well as recruitment of large numbers of participants with these phenotypes. He directs a functional genomics laboratory where he and his research team attempt to discern the biology of pathways identified through human genetics studies. He has a strong interest and track record of using translational approaches to use the biological information generated in the lab, for development of novel therapeutic approaches.
In his role as founding director of the Penn Medicine Biobank (PMBB), Dr. Rader expanded his phenotypic interests and is increasingly focused on a genome-first approach to biological discovery. By genotyping and sequencing tens of thousands of consented participants and linking the genome to the phenome at scale, the PMBB has allowed his lab and many others at Penn to explore novel genotype-phenotype associations. As Chair of the Department of Genetics at Penn and Chief of both the pediatric and adult Divisions of Human Genetics at CHOP and Penn respectively, he has a strong commitment to basic genetic discovery as well as implementation of genomic medicine across all ages and ancestral groups. As Associate Director of the Institute for Translational Medicine and Therapeutics (ITMAT) at Penn, Dr. Rader is determined to see human genetics discoveries translated into novel therapeutics for both rare and common disease.
Laboratory Personnel
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Junghyun (Jun) Lim
Professional Masters Student
Junghyun (Jun) Lim
Professional Masters Student
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Other TMHG Clinical Research Personnel
Associated Faculty
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Carolin V. Schneider, MD
Professor/Physician Scientist - RWTH Aachen University
Email Carolin V. Schneider, MD
Carolin V. Schneider, MD
Professor/Physician Scientist - RWTH Aachen University
cschneider@ukaachen.de
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Marijana Vujkovic, PhD MSCE
Research Assistant Professor of Medicine - TMHG
Email Marijana Vujkovic, PhD MSCE
Marijana Vujkovic, PhD MSCE
Research Assistant Professor of Medicine - TMHG
vujkovic@pennmedicine.upenn.edu
