Perelman School of Medicine at the University of Pennsylvania

Topics in Molecular Medicine

Welcome to Topics in Molecular Medicine

Fall, 2018


Topics in Molecular Medicine


Rahul M. Kohli, MD, PhD
Assistant Professor of Medicine (Infectious Disease)

F. Bradley Johnson, MD, PhD
Associate Professor of Pathology and Laboratory Medicine

TiMM is planned as a once-weekly seminar course whose goal is to introduce students to the ways in which biomedical research can provide new insights into clinical medicine and, conversely, how knowledge of clinical disease impacts scientific discovery. Due to space limitations, the course is open only to 1st year Combined Degree (MD/PhD) students. The course will meet for 90 minutes each week. Class will first meet on August 27, 2018.

The course will be in a seminar style. Four students will be assigned to present at each session. Each session has a different faculty member as a preceptor; this faculty member, in consultation with the course directors, has typically chosen one state-of-the-art research paper that provides molecular insight into a topic of clinical relevance. For some select topics more than one paper has been selected if they tell a coordinated story.  The faculty member will meet with the students before the class session to provide additional insight into the topic. The team will present the clinical background of the problem, the scientific background for the paper, critically dissect the data and interpretations in the scientific paper, and discuss its implications. All of the students in the class will be expected to have read the research paper, to contribute a question for discussion, and to participate in the class discussion. Topics assignments for the semester will be made well in advance of the first class.