Perelman School of Medicine at the University of Pennsylvania

Topics in Molecular Medicine

Welcome to Topics in Molecular Medicine

Fall 2020


Rajan Jain, MD
Assistant Professor of Medicine (Cardiology)

Rahul M. Kohli, MD, PhD
Assistant Professor of Medicine (Infectious Disease) 

TiMM is planned as a seminar course whose goal is to introduce students to the ways in which biomedical research can provide new insights into clinical medicine and, conversely, how knowledge of clinical disease impacts scientific discovery. Due to space limitations, the course is open only to 1st year Combined Degree (MD/PhD) students. The course will meet for 60-90 minutes each week. Class will first meet on Friday August 31.

The course will be in a seminar style. The team involved in presentation involves 5-6 students per session, with teams split between presenters and discussants. Each session has a different faculty member as a preceptor; this faculty member, in consultation with the course directors, has chosen one state-of-the-art research paper that provides mechanistic insight into a topic of clinical relevance. The faculty member will meet with the team of students before the class session to provide additional insight into the topic.

The presenters on the team will assemble a 30 min presentation that covers the clinical background of the problem, the scientific background for the paper, and critically dissect the data and interpretations in the scientific paper. This presentation should be made available as a slide show and oral video presentation. All of the students in the class will be expected to have read the research paper, to contribute a question for discussion, and to participate in the class discussion. The discussants will be tasked with leading the 60 min discussion by organizing the submitted questions into discrete, thematically-aligned areas.

Topics assignments for the semester will be made well in advance of the first class.