Topics in Molecular Medicine

Syllabus

CAMB 542-401 | Topics in Molecular Medicine

	Date	Class Time	Faculty Preceptor	Topic	Assigned Reading
1	Friday, September 11	2:30-4:00PM	Mark Kahn, MD	Lessons from the crypt: what COVID taught us about vascular disease	Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19 Sticky dead red blood cells obstruct small vessels
2	Friday, September 25	2:30-4:00PM	Jonathan Miner, MD, PhD	STING-associated immunity	The mutational landscape of STING-induced immunity Activated STING in a Vascular and Pulmonary Syndrome
3	Friday, October 2	2:30-4:00PM	Katharine Bar, MD	Clinical opportunities for CARD8 inflammasome triggering for HIV treatment and cure	CARD8 is an inflammasome sensor for HIV-1 protease activity Beyond Inhibition: A Novel Strategy of Targeting HIV-1 Protease to Eliminate Viral Reservoirs
5	Monday, October 19	2:30-4:00PM	Lucie Guo, MD, PhD		A multi-agent system for automating scientific discovery Complement regulation in the eye: implications for age-related macular degeneration
6	Monday, November 2	2:30-4:00PM	Mark Sellymer, MD, PhD	Chemistry to the Rescue	Chemical remodeling of a cellular chaperone to target the active state of mutant KRAS Daraxonrasib or Chemotherapy in Previously Treated Metastatic Pancreatic Cancer
7	Friday, November 20	2:30-4:00PM	Ana Cristancho, MD, PhD	How Early-Life Environments Shape Lifelong Brain Health: Lessons in Plasticity and Rescue	Dysregulated hippocampal fatty acid metabolism following intermittent hypoxemia-induced neonatal brain injury is rescued by treatment with acetate Early developmental outcome in children born to mothers with obstructive sleep apnea