Weiyan Jia, PhD

Research Interest

My research focus on the development, optimization, and performance of genomic experiments to identify functionally important variation impacting cardiometabolic, anthropometric, and immune related traits in human populations (in subjects from different regions of Africa). I am also working on characterizing the role of genetic variation on gene expression and phenotypes in vitro and in vivo through biochemical, molecular, and cellular assays.

Education

2007 - 2014

2003 - 2007

Ph.D. Genetics, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China
Advisor: Jiayang Li, Ph.D.

B.S. in Biotechnology, Huazhong University of Science & Technology, Wuhan, China

Research Experience

2022 – Present

2020 – 2022

2014 – 2020

Senior Research Investigator
Tishkoff Lab, Department of Genetics, Perelman School of Medicine, University of Pennsylvania

Research Associate (Scientist)
Lin Guo lab, Department of Biochemistry and Molecular Biology, Thomas Jefferson University

Researcher Asociate (Postdoctoral Fellow)
Randal Tibbetts lab, Department of Human Oncology, University of Wisconsin-Madison

Publications & Manuscripts

Kim, S.H., Nichols, K.D., Anderson, E.N., Liu, Y., Ramesh, N., Jia, W., Kuerbis, C.J., Scalf, M., Smith, L.M., Pandey, U.B., et al. Axon guidance pathways modulate neurotoxicity of ALS-associated UBQLN2. bioRxiv 2022.10.31.514355

Jia, W., Kim, S.H., Scalf, M.A., Tonzi, P., Millikin, R.J., Guns, W.M., Liu, L., Mastrocola, A.S., Smith, L.M., Huang, T.T., et al. (2021). Fused in sarcoma regulates DNA replication timing and kinetics. J Biol Chem 297, 101049.

Kim, S.H., Wu, C.-G., Jia, W., Xing, Y., and Tibbetts, R.S. (2021). Roles of constitutive and signal-dependent protein phosphatase 2A docking motifs in burst attenuation of the cyclic AMP response element-binding protein. J Biol Chem 297, 100908.

Jia, W., Li, B., Li, S., Liang, Y., Wu, X., Ma, M., Wang, J., Gao, J., Cai, Y., Zhang, Y., et al. (2016). Mitogen-Activated Protein Kinase Cascade MKK7-MPK6 Plays Important Roles in Plant Development and Regulates Shoot Branching by Phosphorylating PIN1 in Arabidopsis. PLoS Biol. 14, e1002550.