Jason D. Christie, MD, MSCE
Jason D. Christie, MD, MSCE
Associate Professor of Medicine
Department: Medicine
Graduate Group Affiliations
Contact information
Division of Pulmonary and Critical Care Medicine
Hospital of the University of Pennsylvania
Center for Clinical Epidemiology and Biostatistics
University of Pennsylvania School of Medicine
423 Guardian Drive
719 Blockley Hall
Philadelphia, PA 19104
Hospital of the University of Pennsylvania
Center for Clinical Epidemiology and Biostatistics
University of Pennsylvania School of Medicine
423 Guardian Drive
719 Blockley Hall
Philadelphia, PA 19104
Office: (215) 573-3209
Fax: (215) 573-0198
Fax: (215) 573-0198
Email:
jchristi@mail.med.upenn.edu
jchristi@mail.med.upenn.edu
Publications
Links
Search PubMed for articles
Center for Clinical Epidemiology and Biostatistics faculty webpage
Institute for Translational Medicine and Therapeutics
Search PubMed for articles
Center for Clinical Epidemiology and Biostatistics faculty webpage
Institute for Translational Medicine and Therapeutics
Education:
Sc.B. (Chemistry)
Brown University, 1989.
M.D. (Medicine)
Columbia University, 1993.
M.S.C.E. (Clinical Epidemiology)
University of Pennsylvania, 2002.
Permanent linkSc.B. (Chemistry)
Brown University, 1989.
M.D. (Medicine)
Columbia University, 1993.
M.S.C.E. (Clinical Epidemiology)
University of Pennsylvania, 2002.
Description of Research Expertise
Dr. Christie's translational research studies involve the role of oxidative stress, coagulation/fibrinolysis and inflammatory pathways in acute lung injury following lung transplantation (termed primary graft dysfunction); somatic genetic variation; gene expression; and protein biomarkers in the etiology and pathogenesis of acute lung injury in the transplant, sepsis, and trauma populations.Selected Publications
Shah RJ, Diamond JM, Cantu E, Lee JC, Lederer DJ, Lama VN, Orens J, Weinacker A, Wilkes DS, Bhorade S, Wille KM, Ware LB, Palmer SM, Crespo M, Localio AR, Demissie EJ, Kawut SM, Bellamy SL, Christie JD: Latent class analysis identifies distinct phenotypes of primary graft dysfunction after lung transplantation. Chest Page: Epup ahead of print, 2013.Mikkelsen ME, Christie JD, Abella BS, Kerlin MP, Fuchs BD, Schweickert WD, Berg RA, Mosesso VN, Shofer FS, Gaieski DF; for the American Heart Association’s Get With the Guidelines-Resuscitation Investigators: Use of Therapeutic Hypothermia After In-Hospital Cardiac Arrest. Crit Care Med Page: Epup ahead of print, 2013.
Shah RJ, Bellamy SL, Lee JC, Cantu E, Diamond JM, Mangalmurti N, Kawut SM, Ware LB, Christie JD: Early plasma soluble receptor for advanced glycation end-product levels are associated with bronchiolitis obliterans syndrome. Am J Transplant Page: Epup ahead of print, 2013.
Diamond JM, Lee JC, Kawut SM, Shah RJ, Localio AR, Bellamy S, Lederer DJ, Cantu E, Kohl BA, Lama VN, Bhorade S, Crespo M, Demissie E, Sonnett J, Wille K, Orens J, Shah AS, Weinacker A, Arcasoy S, Shah PD, Wilkes DS, Ware LB, Palmer SM, Christie JD; for the Lung Transplant Outcomes Group: Clinical risk factors for primary graft dysfunction after lung transplantation. Am J Respir Crit Care Med Page: Epub ahead of print, 2013.
Meyer NJ, Feng R, Li M, Zhao Y, Sheu CC, Tejera P, Gallop R, Bellamy S, Rushefski M, Lanken PN, Aplenc R, O'Keefe GE, Wurfel MM, Christiani DC, Christie JD: IL1RN Coding Variant Is Associated with Lower Risk of Acute Respiratory Distress Syndrome and Increased Plasma IL1RA. Am J Respir Crit Care Med Page: Epup ahead of print, 2013.
Shah RJ, Diamond JM, Lederer DJ, Arcasoy SM, Cantu E, Demissie EJ, Kawut SM, Kohl B, Lee JC, Sonett J, Christie JD, Ware LB: Plasma Monocyte Chemotactic Protein-1 (MCP-1) levels at 24 hours are a biomarker of primary graft dysfunction following lung transplantation. Transl Research 160(6): 435-42, Dec 2012.
Diamond JM, Porteous MK, Cantu E, Meyer NJ, Shah RJ, Lederer DJ, Kawut SM, Lee J, Bellamy SL, Palmer SM, Lama VN, Bhorade SM, Crespo M, Demissie E, Wille K, Orens J, Shah PD, Weinacker A, Weill D, Arcasoy S, Wilkes DS, Ware LB, Christie JD; Lung Transplant Outcomes Group: Elevated plasma angiopoietin-2 levels and primary graft dysfunction after lung transplantation. PLoS One 7(12): e51932, Dec 2012.
Benden Christian, Ridout Deborah A, Edwards Leah B, Boehler Annette, Christie Jason D, Sweet Stuart C: Body mass index and its effect on outcome in children after lung transplantation. J Heart Lung Transplant Page: In Press, Epub ahead of print, Nov 2012.
Thabut G, Munson J, Haynes K, Marhay MO, Christie JD, Halpern SD: Geographic disparities in access to lung transplantation before and after implementation of the lung allocation score. Am J Transplant 12(11): 3085-93, Nov 2012.
Tejera P, Meyer NJ, Chen F, Feng R, Zhao Y, O'Mahony DS, Li L, Sheu CC, Zhai R, Wang Z, Su L, Bajwa E, Ahasic AM, Clardy PF, Gong MN, Frank AJ, Lanken PN, Thompson BT, Christie JD, Wurfel MM, O'Keefe GE, Christiani DC: Distinct and replicable genetic risk factors for acute respiratory syndrome of pulmonary or extrapulmonary origin. J Med Genet 49(11): 671-80, Nov 2012.