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Anne Rentoumis Cappola, MD, ScM

Anne Rentoumis Cappola, MD, ScM

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Assistant Professor of Medicine
Department: Medicine
Graduate Group Affiliations

Contact information
Division of Endocrinology, Diabetes, and Metabolism
CRB 764
415 Curie Blvd.
Philadelphia, PA 19104-6149
Office: (215) 573-5359
Fax: (215) 898-5408
Education:
B.A. (Biochemistry )
Harvard College (Advanced Standing), Cambridge, MA, 1990.
M.D.
University of Pennsylvania School of Medicine, 1994.
Sc.M. (Clinical Epidemiology)
Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 2001.
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Description of Research Expertise

Anne Rentoumis Cappola, M.D., Sc.M. is an Assistant Professor of Medicine in the Division of Endocrinology Diabetes, and Metabolism, Assistant Director of the Type 2 Diabetes Unit of the Institute of Diabetes, Obesity, and Metabolism (IDOM), Associate Scholar in the Center for Clinical Epidemiology (CCEB), and a Fellow in the Institute on Aging. She has also completed a Master of Science in Clinical Epidemiology from the Johns Hopkins Bloomberg School of Public Health.

Dr. Cappola's research focuses on the hormonal alterations that occur with aging and the clinical impact of these changes, particularly in older women. She is funded by the National Institute on Aging. Current projects include studies of trajectories of DHEAS and IGF-1 in older men and women, the role of androgens in the health of older women, the combined effects of endocrine, inflammatory, and nutritional factors as risk factors for the frailty syndrome; the metabolic changes in men and women who sustain a hip fracture; and the association between subclinical thyroid dysfunction and clinical outcomes in older men and women.

Selected Publications

Cappola AR, Xue QL, Fried LP: Multiple hormonal deficiencies in anabolic hormones are found in frail older women: the Women’s Health and Aging Studies J Gerontol A Biol Sci Med Sci 64(2): 243-8, Feb 2009.

Somwaru LL, Arnold A, Joshi N, Fried, LP, Cappola AR: High frequency of and factors associated with thyroid hormone over-replacement and under-replacement in men and women aged 65 and over. J Clin Endocrinol Metab 94(4): 1342-45, 2009.

Ceresini G, Lauretani F, Maggio M, Ceda GP, Morganti S, Usberti E, Chezzi C, Valcavi R, Bandinelli S, Guralnik JM, Cappola AR, Valenti G, Ferrucci L. : Thyroid function abnormalities and cognitive impairment in elderly people: results of the Invecchiare in Chianti study J Am Geriatr Soc 57(1): 89-93, 2009.

Leng SX, Hung W, Cappola AR, Yu X, Xue QL, Fried LP: White blood cell counts, insulin-like growth factor-1 levels, and frailty in community-dwelling older women. J Gerontol A Biol Sci Med Sci 64(4): 499-502, Apr 2009.

Rodondi N, Bauer DC, Cappola AR, Cornuz J, Robbins J, Fried LP, Ladenson PW, Vittinghoff E, Gottdiener JS, Newman AM : Subclinical thyroid dysfunction, cardiac function and the risk of heart failure: The Cardiovascular Health Study. J Am Coll Cardiol 52(14): 1152-9, 2008.

Cappola AR, Maggio M, Ferrucci L.: Is research on hormones and aging finished? No! Just started! J Gerontol A Biol Sci Med Sci 63(7): 696-8, 2008.

Cappola AR: Subclinical thyroid dysfunction and the heart. J Clin Endocrinol Metab 92(9): 3404-5, 2007.

Cappola AR., Ratcliffe SJ., Bhasin S., Blackman MR., Cauley J., Robbins J., Zmuda J., Harris T., Fried LP.: Determinants of serum total and free testosterone levels in women over the age of 65. J Clin Endocrinol Metab 92(2): 509-16, 2007.

Cappola AR., Fried LP., Arnold AM., Danese MD., Kuller LH., Burke GL., Tracy RP., Ladenson PW.: Thyroid status, cardiovascular risk, and mortality in older adults. JAMA 295(9): 1033-41, Mar 1 2006.

Cappola AR., Xue QL., Walston JD., Leng SX., Ferrucci L., Guralnik J., Fried LP.: DHEAS levels and mortality in disabled older women: the Women's Health and Aging Study I. Journals of Gerontology Series A-Biological Sciences & Medical Sciences 61(9): 957-62, Sep 2006.

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Last updated: 10/22/2009
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