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Jose L. Pascual L., MD, PhD, FACS, FCCM, FRCSC

Jose L. Pascual L., MD, PhD, FACS, FCCM, FRCSC

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Associate Professor of Surgery at the Hospital of the University of Pennsylvania and the Presbyterian Medical Center of Philadelphia
Department: Surgery

Contact information
Division of Trauma & Surgical Critical Care
Perelman School of Medicine at the University of Pennsylvania
51 North 39th St,MOB 1st floor, Suite 120, Room 108
Philadelphia, PA 19104
Office: 215-662-7323
Fax: 215-243-4679
Education:
N/A (Physiology)
McGill University, Montreal, Quebec , 1990.
N/A (Biochemistry)
University of Ottawa, Ottawa, Ontario , 1992.
M.D.
University of Ottawa, Ottawa, Ontario, 1996.
Ph.D.
McGill University, Montreal, Quebec, 2005.
FRCS (C)
McGill University, Montreal, Quebac, 2005.
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Description of Research Expertise

Jose Pascual is a clinical surgeon specialized in trauma and critical care who has a special interest in shock and head injury. His research interests are shared in basic science research where he evaluates, in vivo, through intravital microscopy the real time microcirculation of pia on live rodent brains. He seeks to learn how a variety of insults including head injury and shock affect the microcirculation and how different management strategies influence these changes. This basic science work is translated into several clinical projects both retrospective and prospective evaluating the effects of different osmotherapeutic agents in traumatic brain injured patients as well as the immunemodulating effects of different resuscitation fluids in different forms of shock.

Description of Clinical Expertise

Jose Pascual is an intensivist/surgeon at the University Of Pennsylvania, board certified in the US/Canada. He finished his fellowship in 2007 and his basic science PhD in resuscitation immunobiology, at McGill, in 2005. His thesis investigated the salutary effects of immunemodulating fluids in shock.

As faculty of Medical and Nursing Schools, Jose teaches students, residents, fellows and advance practice providers in several didactic and skills courses. However, most notable is his role as research mentor for medical, nursing and undergraduate students raising questions at the bedside and attempting to answer them through clinical or basic science research projects. In the last 5 years, Jose has mentored 23 research trainees, several of whom have won awards at national/international scientific meetings.

Jose Pascual’s research interests include Traumatic Brain Injury, shock and ICU education through simulation and patient safety initiatives. His TBI laboratory studies immune responses to injury through intravital microscopy of the cerebral microcirculation investigating the role of the neutrophil in injury and shock.

Jose has launched several ICU educational initiatives using simulation integrated within the ICU to teach day-to-day emergent event management by the multidisciplinary team (NPs, MDs, nurses, pharmacists) through learning from errors or near misses. Initiatives relating to videorecorded simulator-generated or real emergent events have been integrated in ICU Quality Improvement efforts and also published.

Selected Publications

Sherma A, Sinha S, Oselkin M, Pascual J, Schuster J,: External carotid pseudoaneurysm due to wound vacuum placement after self-inflicted shotgun blast to face. Podium at 3rd Annual Critical Care Spectacular Case Presentation Competition, Philadelphia Drinker Society,Philadelphia, PA June 2017.

Resnick S, Seamon MJ, Holena DH, Pascual JL, Reilly PM, Martin ND.: Early Declaration of Death by Neurologic Criteria Results in Greater Organ Donor Potential J Surg Res May 2017.

J, Gray J, Miano T, Redline G, Teufel H, Collins T, Pascual-Lopez J, Sylvia M, Martin ND: Pain, Agitation, and Delirium Guidelines: Interprofessional Perspectives to Translate the Evidence. Dimens Crit Care Nurs Page: 36(3):164-173. May/Jun 2017.

Nunn AM, Hatchimonji JS, Holena DN, Seamon MJ, Smith BP, Kaplan LJ, Martin ND, Reilly PM, Schwab CW, Pascual JL: Boarding ICU patients: Are our rounding practices subpar? Am J Surg May 2017.

Nagata K, Browne KD, Suto Y, Kumasaka K, Cognetti J, Johnson VE, Marks J, Smith DH, Pascual JL.: Early Heparin Administration After TBI: Prolonged Cognitive Recovery Associated With Reduced Cerebral Edema and Neutrophil Sequestration. J Trauma Acute Care Surg. 2017 May 22. doi: 10.1097/TA.0000000000001590. J Trauma Acute Care Surg. May 2017.

Kuo LE, Kaufman E, Hoffman RL, Pascual JL, Martin ND, Kelz RR, Holena DN.: Failure-to-rescue after injury is associated with preventability: The results of mortality panel review of failure-to-rescue cases in trauma. PMID: 27788924 Surgery. 2017 Mar;161(3):782-790. doi: 10.1016/j.surg.2016.08.017. Epub 2016 Oct 25. Mar 2017.

Allen SR, Pascual J, Martin N, Reilly P, Luckianow G, Datner E, Davis KA, Kaplan LJ: A Novel Method of Optimizing Patient and Family Centered Care in the ICU Accepted for publication J Trauma Acute Care Surg, 82(3):582-586, Mar 2017.

Hochman BR, Barry ME, Lane-Fall MB, Allen SR, Holena DN, Smith BP, Kaplan LJ, Pascual JL: Handoffs in the Intensive Care Unit. Am J Med Qual. 2017 Mar/Apr;32(2):186-193. Am J Med Qual,Am J Med Qual. 2017 Mar/Apr;32(2):186-193 Mar/Apr 2017.

Chung JJ, Earl-Royal EC, Delgado MK, Pascual JL, Reilly PM, Wiebe DJ, Holena DN.: Where We Fail: Location and Timing of Failure to Rescue in Trauma. Am Surg. 2017 Mar 1;83(3):250-256. Mar 2017.

Nadolski G, Jacovides CL, Pascual JL.: Arteriography for Lower Gastrointestinal Hemorrhage-Reply. JAMA Surg. 2017 Feb 1;152(2):210-211. doi: 10.1001/jamasurg.2016.4262. No abstract available. Feb 2017.

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Last updated: 06/16/2017
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