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Stephen R. Thom, MD, PhD

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Emeritus Professor of Emergency Medicine
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Chief of Hyperbaric Medicine, Institute for Environmental Medicine, University of Pennsylvania Philadelphia, PA
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Medical Director, Pennstar Flight Program, Hospital of the University of Pennsylvania, Philadelphia, PA
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Professor, Emergency Medicine in Pediatrics, Children's Hospital of Philadelphia
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Department: Emergency Medicine
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University of Pennsylvania
2c Institute for Environmental Medicine
1e 1 John Morgan Building
45 36th Street and Hamilton Walk
Philadelphia, PA 19104-6068
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Email: sthom@mail.med.upenn.edu
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1f Graduate Group Affiliations 8 a
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13 Education:
21 9 B.A. 14 (Biology) c
3f University of Rochester, Rochester, NY, 1975.
 21 a Ph.D. 19 (Microbiology) c
3f University of Rochester, Rochester, NY, 1981.
 21 9 M.D. c
3f University of Rochester, Rochester, NY, 1981.
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1f Post-Graduate Training
24 57 Intern in Medicine, University of Maryland, Baltimore, MD, 1981-1982.
 24 68 Resident in Emergency Medicine, UCLA Hospital and Clinics, Los Angeles, CA, 1982-1984.
 24 6a Fellowship in Hyperbaric Medicine, Memorial Medical Center, Long Beach, CA. , 1982-1984.
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17 Certifications
28 48 Diplomate, American Board of Emergency Medicine, 1987.
 28 50 Additional Certification-Undersea & Hyperbaric Medicine, 1999.
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Selected Publications

13e Thom Stephen R, Yang Ming, Bhopale Veena M, Huang Shaohui, Milovanova Tatyana N: Microparticles initiate decompression-induced neutrophil activation and subsequent vascular injuries. Journal of applied physiology (Bethesda, Md. : 1985) Oct 2010.

 156 Thom Stephen R, Bhopale Veena M, Milovanova Tatyana M, Hardy Kevin R, Logue Christopher J, Lambert David S, Troxel Andrea B, Ballard Kerri, Eisinger Dominic: Plasma biomarkers in carbon monoxide poisoning. Clinical toxicology (Philadelphia, Pa.) 48(1): 47-56, Jan 2010.

 e5 Thom Stephen R: Oxidative stress is fundamental to hyperbaric oxygen therapy. Journal of applied physiology (Bethesda, Md. : 1985) 106(3): 988-95, Mar 2009.

 17f Milovanova Tatyana N, Bhopale Veena M, Sorokina Elena M, Moore Jonni S, Hunt Thomas K, Hauer-Jensen Martin, Velazquez Omaida C, Thom Stephen R: Hyperbaric oxygen stimulates vasculogenic stem cell growth and differentiation in vivo. Journal of applied physiology (Bethesda, Md. : 1985) 106(2): 711-28, Feb 2009.

 1a7 Milovanova Tatyana N, Bhopale Veena M, Sorokina Elena M, Moore Jonni S, Hunt Thomas K, Hauer-Jensen Martin, Velazquez Omaida C, Thom Stephen R: Lactate stimulates vasculogenic stem cells via the thioredoxin system and engages an autocrine activation loop involving hypoxia-inducible factor 1. Molecular and cellular biology 28(20): 6248-61, Oct 2008.

 115 Thom Stephen R, Bhopale Veena M, Mancini D Joshua, Milovanova Tatyana N: Actin S-nitrosylation inhibits neutrophil beta2 integrin function. The Journal of biological chemistry 283(16): 10822-34, Apr 2008.

 e1 TN Milovanova, JS Moore, TK Hunt, SR Thom: Stem cell mobilization and vasculogenesis stimulated by hyperoxia and lactate. Experimental Biology May 2007.

 d7 ST Han, VM Bhopale, SR Thom: Xanthine oxidorecductase and neurological sequelae of carbon monoxide poisoning. Toxicol Lett 170: 115-115, 2007.

 144 KA Gallagher, MD Goldstein, DG Buerk, A Nedeau, M Xaio, H Chen, SR Thom, ZL Liu, OC Valazquez: Diabetic impairments in NO-mediated endothelial progenitor cell mobilization and homing are reversed by hyperoxia and SDF. Clin Invest 117: 1249-1259, 2007.

 85 Thom, S.R., Bhopale, V.M., Velazquez, O.C., Goldstein, L.J., Thom, L.H., and Buerk, D.G. 53 : Stem cell mobilization by hyperbaric oxygen. Experimental Biology 21 April 2006.

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