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John Y.K. Lee, M.D.

Associate Professor of Neurosurgery at the Pennsylvania Hospital
Attending Neurosurgeon, Hospital University of Pennsylvania, Philadelphia, PA
Attending Neurosurgeon, Pennsylvania Hospital, University of Pennsylvania, PA
Medical Director, Penn Gamma Knife at Pennsylvania Hospital
Attending Neurosurgeon, Children's Hospital of Philadelphia, Philadelphia PA
Unit Based Clinical Leadership - Physician Representative, Pennsylvania Hospital, Philadelphia PA
Department: Neurosurgery

Contact information
Department of Neurosurgery
Pennsylvania Hospital
Washington Square West Building
235 S. 8th Street
Philadelphia, PA 19106
Office: 215-829-5189
Fax: 215-829-6645
B.S. (Molecular Biophysics and Biochemistry)
Yale University, 1994.
Rutgers - Robert Wood Johnson Medical School, New Jersey, 1998.
M.S.C.E. (Clinical Epidemiology)
University of Pennsylvania, 2015.
Post-Graduate Training
Intern in Surgery, University of Pittsburgh, Pennsylvania, 1998-1999.
Resident in Neurological Surgery, University of Pittsburgh, Pennsylvania, 1999-2004.
Chief Resident in Neurological Surgery, University of Pittsburgh, Pennsylvania, 2004-2005.
Fellow (Functional Neurosurgery), Cleveland Clinic, Ohio , 2005-2006.
Gamma Knife Stereotactic Radiosurgery, University of Pittsburgh, 2005.
Board Certified, American Board of Neurological Surgery, 2009.
Cyberknife Stereotactic Radiosurgery, Accuray, 2011.
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Description of Clinical Expertise

Dr. Lee has a passion for minimally invasive ways to treat brain and skull base tumors. This passion is expressed as a commitment to endoscopic approaches to remove pituitary, clival, acoustic neuromas and other skull-base tumors. Another expression of his interest in minimally invasive methods is his devotion to stereotactic radiosurgery, eg. "incision-less" brain surgery.

In addition to brain tumors, Dr. Lee is committed to the comprehensive treatment of patients with craniofacial neuralgias, including trigeminal neuralgia, glossopharyngeal neuralgia, and hemifacial spasm. Dr. Lee uses minimally invasive, fully endoscopic surgical procedures including microvascular decompression (Jannetta procedure) and stereotactic radiosurgery to cure these disorders.

Selected Publications

Sandhu S, Lee JYK: Measurement of Trigeminal Neuralgia Pain. Penn Facial Pain Scale. Neurosurgery Clinics of North America 27(3): 327-336, July 2016.

Piazza M, Lee JYK: Endoscopic and Microscopic Microvascular Decompression. Neurosurgery Clinics of North America 27(3): 305-313, July 2016.

Craig JR, Petrov D, Khalili S, Brooks SG, Lee JYK, Adappa ND, Palmer JN : The nasofrontal beak: A consistent landmark for superior septectomy during Draf III drill out American Journal of Rhinology and Allergy 30(3): 230-234, May 2016.

Craig JR, Zhao K, Doan N, Khalili S, Lee JYK, Adappa ND, Palmer JN: Cadaveric validation study of computational fluid dynamics model of sinus irrigations before and after sinus surgery. International Forum of Allergy and Rhinology 6(4): 423-428, April 2016.

Farquhar D, Kim L, Worrall, D, Chiu A, Lee JY, Khalili S, Grady S, O'Malley BW, Kennedy DW, Newman JG, Palmer JN, Adappa ND : Propensity score analysis of endoscopic and open approaches to malignant paranasal and anterior skull base tumor outcomes. Laryngoscope 2016.

Chowdhury IH, Ojerholm E, McMillan MT, Miller D, Kolker JD, Kurtz G, Dorsey JF, Nagda SN, Geiger, GA, Brem S, O'Rourke DM, Zager EL, Gangadhar T, Schuchter L, Lee, JYK, Alonso-Basanta M : Novel risk scores for survival and intracranial failure in patients treated with radiosurgery alone to melanoma brain metastases. Radiation Oncology 10(1), December 2015.

Ghosh A., Hatten K, Learned KO, Rizzi MD, Lee, JY, Storm, PB, Palmer JN, Adappa ND : Pediatric nasoseptal flap reconstruction for suprasellar approaches. Laryngoscope 125(11): 2451-2456, November 2015.

Vogel J, Ojerholm E, Hollander A Briola C , Mooij R, Bieda M , Kolker J , Nagda S , Geiger G, Dorsey J, Lustig R , O'Rourke DM , Brem S, Lee JYK, Alonso-Basanta M : Intracranial control after Cyberknife radiosurgery to the resection bed for large brain metastases Radiation Oncology 10(1), October 2015.

Lee JYK, Sandhu S, Miller D, Solberg T, Dorsey JF, Alonso-Basanta M : Higher dose rate Gamma Knife radiosurgery may provide earlier and longer-lasting pain relief for patients with trigeminal neuralgia. Journal of Neurosurgery 123(4): 961-968, October 2015.

Craig JR, Lee JYK, Petrov, D, Mehta S, Palmer JN, Adappa ND: Two versus Four-handed techniques for endonasal resection of orbital apex tumors. American Journal of Rhinology and Allergy 29(5): 383-388, September 2015.

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Last updated: 07/12/2016
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