Department of Hematology

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Angela M De Michele, MD MSCE

Associate Professor of Medicine at the Hospital of the University of Pennsylvania
Senior Scholar
Associate Director
Co-Leader
Co-Director
Department: Medicine

Contact information
Perelman Center for Advanced Medicine
3 West Pavilion
3400 Civic Center Boulevard
Philadelphia, PA 19104
Office: 215-349-5730
Fax: 215-615-3349
Graduate Group Affiliations
Education:
B.A. (Biochemistry)
Brown University, 1988.
M.D. (Medicine)
Washington University School of Medicine, 1991.
M.S.C.E. (Clinical Epidemiology)
University of Pennsylvania, School of Medicine, 2001.
Post-Graduate Training
Intern in Obstetrics and Gynecology, Hospital of the University of Pennsylvania, 1991-1992.
Resident in Medicine, Hospital of the University of Pennsylvania, 1992-1994.
Visiting Clinical Fellow, Istituto di Ematologia Seràgnoli, Institute of Hematology, Università degli Studi di Bologna, 1994-1995.
Fellowship, Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, 1995-1998.
Certifications
National Board of Medical Examiners, 1992.
American Board of Internal Medicine (Medicine), 1995.
American Board of Internal Medicine (Onc Subspecialty), 1998.
American College of Epidemiology , 2002.
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Description of Research Expertise

breast cancer, biomarkers, clinical trials, pharmacogenetics, cytokines, host immunogenetics, cancer survivorship, molecular epidemiology

Description of Clinical Expertise

breast cancer, neoadjuvant therapy, menopausal symptoms related to cancer, cancer survivorship

Selected Publications

Su, H. I., DeMichele, A: Chemotherapy related amenorrhea and hormonal measures of ovarian reserve in young breast cancer survivors after adjuvant chemotherapy Cancer 2009 (in press).

Brunelli SM, DeMichele A, Guevara J, Berlin J: Systematic Review and Meta-Analysis. Textbook of Clinical Trials 2009 (In Press).

Mao JJ, Stricker CT, Bruner D, Xie SX, Bowman MA, Farrar JT, Greene BT, DeMichele A : Patterns and Risk Factors Associated with Aromatase Inhibitor Related Arthralgia among Breast Cancer Survivors. Cancer Epub ahead of print, June 2009

Solin LJ, Harris E, Orel S, DeMichele A, Tchou J: Loco-Regional Recurrence After Breast Conservation Therapy or Mastectomy. Diseases of the Breast, 3rd Edition. Lippman M, Morrow M, Osborne K (eds.). Lippincott Williams and Wilkens, 2009

Kim, S., Hagemann, A., DeMichele, A: Immuno-modulatory gene polymorphisms and outcome in breast and ovarian cancer. Immunologic Investigations 38: 324-40, 2009

Mao JJ, Bruner D, Stricker CT, Farrar JT, Xie SX, Bowman MA, Pucci D, Han X, DeMichele A. : Feasibility study of electro-acupuncture for aromatase inhibitor related arthralgia in breast cancer. Integrated Cancer Therapies 8: 123-9, 2009

Dunn L, DeMichele A.: Genomic Predictors of Outcome and Treatment Response in Breast Cancer. Molecular Diagnosis and Therapy 13(2): 73-90, June 2009.

DeMichele, A., Gray, R., Horn, M., Chen, J., Aplenc, R., Vaughan, W. P., Tallman, M. S.: Host genetic variants in the interleukin-6 promoter predict poor outcome in patients with estrogen receptor-positive, node-positive breast cancer. Cancer Res 69(10): 4184-91, May 2009.

DeMichele, A., Fox, K. R.: Optimizing outcomes with bevacizumab by better targeting patients and tumors. Oncology (Williston Park) 23(4): 339-40, April 2009.

Gray, S. W., Armstrong, K., Demichele, A., Schwartz, J. S., Hornik, R. C.: Colon cancer patient information seeking and the adoption of targeted therapy for on-label and off-label indications. Cancer 115(7): 1424-34, April 2009.

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Last updated: 11/06/2009
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