Angela M DeMichele, MD MSCE
Associate Professor of Medicine at the Hospital of the University of Pennsylvania
Senior Scholar, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania
Co-Leader, Breast Cancer Program, Abramson Cancer Center, University of Pennsylvania
Program Leader, Doris Duke Clinical Research Fellowship Program, University of Pennsylvania
Department: Medicine
Contact information
Perelman Center for Advanced Medicine
3 West Pavilion
3400 Civic Center Boulevard
Philadelphia, PA 19104
3 West Pavilion
3400 Civic Center Boulevard
Philadelphia, PA 19104
Office: 215-349-5730
Fax: 215-615-3349
Fax: 215-615-3349
Email:
dma@mail.med.upenn.edu
dma@mail.med.upenn.edu
Graduate Group Affiliations
Education:
B.A. (Biochemistry)
Brown University, 1988.
M.D. (Medicine)
Washington University School of Medicine, 1991.
M.S.C.E. (Clinical Epidemiology)
University of Pennsylvania, School of Medicine, 2001.
B.A. (Biochemistry)
Brown University, 1988.
M.D. (Medicine)
Washington University School of Medicine, 1991.
M.S.C.E. (Clinical Epidemiology)
University of Pennsylvania, School of Medicine, 2001.
Post-Graduate Training
Intern in Obstetrics and Gynecology, Hospital of the University of Pennsylvania, 1991-1992.
Resident in Medicine, Hospital of the University of Pennsylvania, 1992-1994.
Visiting Clinical Fellow, Istituto di Ematologia Seràgnoli, Institute of Hematology, Università degli Studi di Bologna, 1994-1995.
Fellowship, Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, 1995-1998.
Intern in Obstetrics and Gynecology, Hospital of the University of Pennsylvania, 1991-1992.
Resident in Medicine, Hospital of the University of Pennsylvania, 1992-1994.
Visiting Clinical Fellow, Istituto di Ematologia Seràgnoli, Institute of Hematology, Università degli Studi di Bologna, 1994-1995.
Fellowship, Hematology-Oncology, Department of Medicine, Hospital of the University of Pennsylvania, 1995-1998.
Certifications
National Board of Medical Examiners, 1992.
American Board of Internal Medicine (Medicine), 1995.
American Board of Internal Medicine (Onc Subspecialty), 1998.
American College of Epidemiology , 2002.
Permanent linkNational Board of Medical Examiners, 1992.
American Board of Internal Medicine (Medicine), 1995.
American Board of Internal Medicine (Onc Subspecialty), 1998.
American College of Epidemiology , 2002.
Description of Research Expertise
breast cancer, biomarkers, clinical trials, pharmacogenetics, cytokines, host immunogenetics, cancer survivorship, molecular epidemiologyDescription of Clinical Expertise
breast cancer, neoadjuvant therapy, menopausal symptoms related to cancer, cancer survivorshipSelected Publications
Speck RM, DeMichele A, Farrar JA, Hennessy S, Mao JJ, Stineman MG and Barg FK: Scope of symptoms and self-management strategies for chemotherapy-induced peripheral neuropathy in breast cancer patients Supportive Care in Cancer Epub ahead of print, January 2012.Esserman LJ, Berry DA, DeMichele A, Carey L, Davis SE, Buxton ME, Hudis C, Gray J, Perou C, Yau C, Livasy C, Krontiras H, Montgomery L, Tripathy D, Lehman C, Liu MC, Olopade OI, Rugo HS, Carpenter JT, Dressler LJ, Chhieng D, Singh B, Mies C, Rabban J, Chen Y, Giri D, van ‘t Veer L, and Hylton N on behalf of the I-SPY 1 TRIAL Investigators.: Pathologic Complete Response Predicts Recurrence-Free Survival More Effectively by Cancer Subset: Results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657). Journal of Clinical Oncology In press 2012.
Freidman C, DeMichele A, Su HI, Feng R, Kapoor S, Desai K, Mao JJ: Vitamin D Deficiency in Post-menopausal Breast Cancer Survivors. Journal of Women's Health In press 2012.
Esserman LJ, Berry DA, Cheang MC, Yau C, Perou CM, Carey L, Demichele A, Gray JW, Conway-Dorsey K, Lenburg ME, Buxton MB, Davis SE, Van't Veer LJ, Hudis C,Chin K, Wolf D, Krontiras H, Montgomery L, Tripathy D, Lehman C, Liu MC, Olopade OI, Rugo HS, Carpenter JT, Livasy C, Dressler L, Chhieng D, Singh B, Mies C, Rabban J, Chen YY, Giri D, Au A, Hylton N; The I-SPY 1 TRIAL Investigators. : Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657). Breast Cancer Research and Treatment [Epub ahead of print], December 2011
Flaherty KT, Lorusso PM, Demichele AM, Abramson V, Courtney R, Randolph Shaik MN, Wilner K, O'Dwyer PJ, Schwartz GK.: Phase 1, Dose-escalation Trial of the Oral Cyclin-dependent Kinase 4/6 Inhibitor PD 0332991, Administered Using a 21-day Schedule in Patients with Advanced Cancer. Clin Cancer Res [Epub ahead of print], November 2011.
Palmer SC, Taggi A, Demichele A, Coyne JC. : Is screening effective in detecting untreated psychiatric disorders among newly diagnosed breast cancer patients? Cancer [Epub ahead of print], October 2011.
Galantino ML, Desai K, Greene L, Demichele A, Stricker CT, Mao JJ. : . Impact of Yoga on Functional Outcomes in Breast Cancer Survivors With Aromatase Inhibitor-Associated Arthralgias. Integr Cancer Ther [Epub ahead of print], July 2011.
Lin C, Buxton MB, Moore D, Krontiras H, Carey L, Demichele A, Montgomery L, Tripathy D, Lehman C, Liu M, Olapade O, Yau C, Berry D, Esserman LJ; I-SPY TRIAL Investigators. : Locally advanced breast cancers are more likely to present as Interval Cancers: results from the I-SPY 1 TRIAL (CALGB 150007/150012, ACRIN6657, InterSPORE Trial). Breast Cancer Res Treat. [Epub ahead of print], July 2011.
Hatzis C, Pusztai L, Valero V, Booser D, Esserman L, Lluch A, Tidaurre T, Holmes F, Souchon E, Wang H, Martin M, Cotrina J, Gomez H, Hubbard R, Chacon J, Ferrer-Lozano J, Dyer R, Buxton M, Gong Y, Wu Y, Ibrahim N, Andreopoulou E, Ueno N, Hunt K, Yang W, Nazario A, DeMichele A, O'Shaughnessy J, Hortobagyi G, Symmans WF.: A Genomic Predictor of Response and Survival Following Taxane-Anthracycline Chemotherapy for Invasive Breast Cancer. Journal of the American Medical Association 305(18): 1873-1881, May 2011.
Su HI, Chung K, Sammel MD, Gracia CR, Demichele A.: Antral follicle count provides additive information to hormone measures for determining ovarian function in breast cancer survivors. Fertility and Sterility 95(5): 1857-9, April 2011.
