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David M. Raizen
David M. Raizen, MD, PhD
Assistant Professor of Neurology
Department: Neurology
Graduate Group Affiliations
Contact information
Dept Neurology
462 Stemmler Hall
415 Curie Blvd
Philadelphia, PA 19104-4283
462 Stemmler Hall
415 Curie Blvd
Philadelphia, PA 19104-4283
Email:
raizen@mail.med.upenn.edu
raizen@mail.med.upenn.edu
Publications
Education:
BA (Biochemistry)
University of Texas at Austin, 1989.
PhD (Neuroscience)
University of Texas Southwestern, 1997.
MD (Medicine)
University of Texas Southwestern, 1997.
Permanent linkBA (Biochemistry)
University of Texas at Austin, 1989.
PhD (Neuroscience)
University of Texas Southwestern, 1997.
MD (Medicine)
University of Texas Southwestern, 1997.
Description of Research Expertise
C. elegans behavioral genetics. Regulation of sleep-like states. Function of sleep and sleep-like states.Description of Clinical Expertise
Sleep disorders: In particular disorders of sleep regulation and restless leg syndrome.Selected Publications
Dabbish NS, Raizen DM.: GABAergic synaptic plasticity during a developmentally regulated sleep-like state in C. elegans. Journal of Neuroscience 31(44): 15932-15943, Nov 2011.Chuang HS, Raizen DM, Lamb A, Dabbish N, Bau HH.: Dielectrophoresis of Caenorhabditis elegans. Lab on Chip 11(4): 599-604, Feb 2011.
Zimmerman JE, Raizen DM, Maycock MH, Maislin G, Pack AI.: A video method to study Drosophila sleep. Sleep 31(11): 1587-1598, November 2008.
David M. Raizen, John E. Zimmerman, Matthew H. Maycock, Uyen D. Ta, Young-jai You, Meera V. Sundaram & Allan I. Pack: Lethargus is a Caenorhabditis elegans sleep-like state. Nature 451, January 2008.
You, Y., Kim, J., Raizen, D. M., and Avery, L.: Insulin, cGMP and TGF-ß signals regulate food intake and quiescence in C. elegans: a model for satiety Cell Metabolism 7: 249-257, 2008.
Zimmerman, J. E., Raizen, D. M., Shockley, K., Churchill, G. A., and Pack, A. I.: Temporal changes in gene expression with sleep and wake in the Drosophila brain. Physiological Genomics 27(3): 337-350, September 2006.
Raizen, D. M., Cullison, K. M., Pack, A. I, and Sundaram, M. V.: A novel gain-of-function mutant of the cGMP-dependent protein kinase egl-4 affects multiple physiological processes in C. elegans. Genetics 173(1): 177-187, May 2006.
Raizen, D. M., Brooks-Kayal, A., Steinkrauss, L., Tennekoon, G. I., Stanley, C. A., and Kelly, A.: Central nervous system hyperexcitability associated with glutamate dehydrogenasae gain of function mutations. Journal of Pediatrics 146(3): 388-394, March 2005.
McKay, J. P., Raizen, D. M., Gottschalk, A., Schafer, W. R., and Avery, L.: eat-2 and eat-18 are required for nicotinic neurotransmission in the C. elegans pharynx. Genetics 166(1): 161-169, January 2004.
Taylor, R. A., Virgilio, J. A., Shapiro, M., Raizen, D. M., Hunt, J., Rook, A., and Bagg, A.: T-cell receptor gamma-chain gene PCR to diagnose CNS involvement by cutaneous T-cell lymphoma. Journal of Molecular Diagnostics 4(2): 118-120, 2002.
