David M. Raizen, MD, PhD
Assistant Professor of Neurology
Department: Neurology
Graduate Group Affiliations
Contact information
Dept Neurology
464 Stemmler
36th and Hamilton Walk
Philadelphia, PA 19104-4283
464 Stemmler
36th and Hamilton Walk
Philadelphia, PA 19104-4283
Office: 215-746-4809
Fax: 215-746-4814
Fax: 215-746-4814
Email:
raizen@mail.med.upenn.edu
raizen@mail.med.upenn.edu
Education:
BA (Biochemistry)
University of Texas at Austin, 1989.
PhD (Neuroscience)
University of Texas Southwestern, 1997.
MD (Medicine)
University of Texas Southwestern, 1997.
Permanent linkBA (Biochemistry)
University of Texas at Austin, 1989.
PhD (Neuroscience)
University of Texas Southwestern, 1997.
MD (Medicine)
University of Texas Southwestern, 1997.
Description of Research Expertise
C. elegans behavioral genetics. Regulation of sleep-like states. Function of sleep and sleep-like states.Description of Clinical Expertise
Sleep disorders: In particular disorders of sleep regulation and restless leg syndrome.Selected Publications
David M. Raizen, John E. Zimmerman, Matthew H. Maycock, Uyen D. Ta, Young-jai You, Meera V. Sundaram & Allan I. Pack: Lethargus is a Caenorhabditis elegans sleep-like state. Nature 451, January 2008.Raizen DM, Mason TB, Pack AI.: Genetic basis for sleep regulation and sleep disorders. Seminars in Neurology 26(5): 467-483, November 2006.
Raizen, D. M., Cullison, K. M., Pack, A. I, and Sundaram, M. V.: A novel gain-of-function mutant of the cGMP-dependent protein kinase egl-4 affects multiple physiological processes in C. elegans. Genetics 173(1): 177-187, May 2006.
Zimmerman, J. E., Raizen, D. M., Shockley, K., Churchill, G. A., and Pack, A. I.: Temporal changes in gene expression with sleep and wake in the Drosophila brain. Physiological Genomics 27(3): 337-350, September 2006.
Raizen, D. M., Brooks-Kayal, A., Steinkrauss, L., Tennekoon, G. I., Stanley, C. A., and Kelly, A.: Central nervous system hyperexcitability associated with glutamate dehydrogenasae gain of function mutations. Journal of Pediatrics 146(3): 388-394, March 2005.