David F. Dinges
David F. Dinges, Ph.D.
Director, Unit for Experimental Psychiatry
Department of Psychiatry
University of Pennsylvania School of Medicine
1013 Blockley Hall
423 Guardian Drive
Philadelphia, PA 19104-6021
Saint Benedict's College, Honors, 1971.
M.S. (Physiological Psychology)
Saint Louis University, 1974.
Washington University, Central Institute for the Deaf, 1975.
Ph.D. (Physiological Psychology)
Saint Louis University, 1976.
University of Pennsylvania , 1993.
Description of Research ExpertiseSleep; chronobiology; human neurobehavioral functions; cognitive performance; psychophysiological asssessment
Description of Clinical Expertisepathological and excessive sleepiness
Description of Other Expertisehuman behavior and performance functioning in space flight
Selected PublicationsWeljie, A.M., Meer, P., Goel, M., Sengupta, A., Kayser, M.S., Abel, T. Birnbaum, M.J., Dinges, D.F., Sehgal, A.M: Oxalic acid and diacylglycerol 36:3 are cross-species markers of sleep debt. Proceedings of the National Academies of Sciences of the USA. PNAS Early Edition January 2015.
Fang, Z., Zhu, S., Hu, S., Ma, N., Shi, H., Goel, N., Detre, J.A., Dinges, D.F., Rao, H.: Disruption and recovery of spontaneous brain connectivity and memory following sleep deprivation. Scientific Reports 5, 2015.
Ma, N., Dinges, D.F., Basner, M., Rao H: How acute total sleep loss affects the attending brain: A meta-analysis of neuroimaging studies. SLEEP 38(2), 2015.
Goel, G., Basner, M., Dinges, D.F.: Phenotyping of neurobehavioral vulnerability to circadian phase during sleep loss. Chapter 13, Methods in Enzymology 552: 285-308, 2015.
Spaeth, A.M., Dinges, D.F., Goel, M. : Sex and race differences in caloric intake during sleep restriction in healthy adults. American Journal of Clinical Nutrition Page: 1-8, June 2014.
Minkel, J.D., Moreta, M., Muto, J., Htaik, O., Jones, C., Basner, M., Dinges, D.F.: Sleep deprivation potentiates HPA axis stress reactivity in healthy adults. Health Psychology (Online First Publication) May 2014.
Yi, B., Rykova, M., Feuerecker, M., Jäger, B., Ladinig, C., Basner, M., Hörl, M., Matzel, S., Kaufmann, I., Strewe, C., Nichiporuk, I., Vassilieva, G., Rinas, K., Baatout, S., Schelling, G., Thiel, M., Dinges, D.F., Morukov, B., Choukèr: 520-d isolation and confinement simulating a flight to Mars reveals heightened immune responses and alterations of leukocyte phenotype. Brain, Behavior, and Immunity April 2014.
Basner, M., Dinges, D.F., Mollicone, D.J., Savelev, I., Ecker, A.J., Di Antonio, A., Jones, C.W., Hyder, E., Kan, K., Morukov, B.V., Sutton, J.P. : Psychological and behavioral changes during confinement in a 520-day simulated interplanetary mission to Mars. PLoS ONE 9(3): e93298, March 2014.
Goel, N., Abe, T., Braun, M.E., Dinges, D.F. : Cognitive Workload and Sleep Restriction Interact to Influence Sleep Homeostatic Responses. SLEEP 37(11): 1745-1756, 2014.
Basner, M., Spaeth, A., Dinges, D.F. : Sociodemographic characteristics and waking activities and their role in the timing and duration of sleep. SLEEP 37(12): 1889-1906, 2014.