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Robert Gordon Kalb

Professor of Neurology
Department: Neurology
Graduate Group Affiliations

Contact information
Children's Hospital of Philadelphia
Abramson Research Center #814
3615 Civic Center Boulevard
Philadelphia, PA 19104
Office: 215 590 0691
Fax: 267 426 5165
B.A. (Biology)
Wesleyan University , 1978.
MD (Medicine)
Cornell University Medical College, 1982.
Post-Graduate Training
Intern in Medicine, Montefiore Hospital, Bronx, NY, 1982-1983.
Resident in Medicine, Montefiore Hospital, Bronx, NY, 1983-1984.
Resident in Neurology, Yale-New Haven Hospital, 1984-1987.
Postdoctoral Fellow, Department of Neurobiology, Yale University, New Haven, CT, 1987-1990.
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Description of Clinical Expertise

I am a Board Certified Adult Neurologist who has been in active and continuous practice since 1987. I have facility in the treatment of a broad range of Neurological Disorders. I have special expertise in the diagnosis and management of ALS patients.

Description of Research Expertise

My research areas of expertise related to neuro-degenerative diseases and nervous system development.

In the diseases arena, I have particular proficiency in the molecular and cellular underpinning of adult-onset neurodegenerative pathophysiology. there is an emerging interest in the role of intermediary metabolism and aging in relation to neurodegenerative diseases and I am specifically adept in these processes.

In the development arena, I have expertise in the cellular and molecular basis of activity-dependent development. In addition, spinal cord development is a special strong suit of mine.

In both arenas, I have a comprehensive and up-to-date understanding of how the fields have developed and the most current research.

Selected Publications

Fryer, H. J. L., Knox, R. J., Strittmatter, S. M., and Kalb, R. G. : Excitotoxic death of a subset of embryonic rat motor neurons in vitro. J. Neurochem. 72: 500-513, 1999.

Tanaka, M, Treloar, H., Kalb, R.G.,, Greer, C. A., and Stephen M. Strittmatter, S.M. : Go protein-dependent survival of primary accessory olfactory neurons. PNAS 96: 14106-14111, 1999.

Nakamura, F., Tanaka, M., Takahashi, T., Kalb, R.G. and Strittmatter, S.M. : Neuropilin-1 extracellular domains mediate semaphorin D/III-induced growth cone collapse. Neuron 21: 1-20, 1998.

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Last updated: 08/08/2014
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