The Cardiovascular Metabolism Unit in the IDOM is focused on the intersection between metabolism and cardiovascular disease. Its major focus is to bring together investigators and clinicians who are interested in the interface between metabolism and cardiovascular disease in order to facilitate basic, translational, and clinical research in this area. As such, the Cardiovascular Metabolism Unit will provide a concrete bridge between the IDOM and the new Cardiovascular Institute, as well as interface with the new Institute for Translational Medicine and Therapeutics.

Specific areas of focus within the Cardiovascular Metabolism Unit are:

  1. The etiology, pathogenesis, complications, and management of the metabolic syndrome.
  2. The etiology and pathogenesis of and development of novel therapeutic approaches to lipid and lipoprotein disorders.
  3. The intersection between insulin resistant and dyslipidemic states with atherosclerosis in animal models and humans.
  4. The etiology and treatment of fatty liver, particularly in insulin resistant states.
  5. The etiology, pathogenesis, and therapy of lipotoxic cardiomyopathy

Core activities of the Cardiovascular Metabolism Unit include a monthly meeting to discuss new translational research initiatives as well as monthly seminar series focused on both external and internal speakers. All basic scientists, translational and clinical researchers, and clinicians interested in the intersection between metabolic disorders and cardiovascular disease are welcome to be part of this unit.

Cardiovascular Metabolism Unit Members


Dan Rader, MD

Dan Rader, M.D.
Cardiovascular Metabolism Unit

Zoltan Arany

Zoltan Arany, M.D., Ph.D.
Cardiovascular Metabolism Unit