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Jason D. Christie, MD, MSCE

Robert M. Kotloff/Nancy Blumenthal Professor for Advanced Lung Disease
Department: Medicine
Graduate Group Affiliations

Contact information
Division of Pulmonary and Critical Care Medicine
Hospital of the University of Pennsylvania
Center for Clinical Epidemiology and Biostatistics
University of Pennsylvania School of Medicine
423 Guardian Drive
221 Blockley Hall
Philadelphia, PA 19104
Office: (215) 573-3209
Fax: (215) 573-0198
Sc.B. (Chemistry)
Brown University, 1989.
M.D. (Medicine)
Columbia University, 1993.
M.S.C.E. (Clinical Epidemiology)
University of Pennsylvania, 2002.
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Description of CVI Expertise

CVI Program Unit(s):
Pulmonary Vascular Disease

CVI Research Description:
My research focus is the molecular epidemiology of acute lung inury and
ischemia reperfusion injury in the trauma and lung transplantaion populations.

Selected Publications

Tao JQ, Sorokina EM, Vazquez Medina JP, Mishra MK, Yamada Y, Satalin J, Nieman GF, Nellen JR, Beduhn B, Cantu E, Habashi NM, Jungraithmayr W, Christie JD, Chatterjee S.: Onset of Inflammation with Ischemia: Implications for Donor Lung Preservation and Transplant Survival. American Journal of Transplantation March 2016 [Epub ahead of print]

Shashaty MGS, Reilly JP, Sims CA, Holena DN, Qing D, Forker CM, Hotz MJ, Meyer NJ, Lanken PN, Feldman HI, Christie JD, Mangalmurti NS: Plasma Levels of Receptor Interacting Protein Kinase-3 (RIP3), an Essential Mediator of Necroptosis, are Associated with Acute Kidney Injury in Critically Ill Trauma Patients. Shock 46(2): 139-43, Aug 2016.

Diamond JM, Arcasoy S, McDonnough JA, Sonett JR, Bacchetta M, D'Ovidio F, Cantu E, Bermudez CA, McBurnie A, Rushefski M, Kalman LH, Oyster M, D'Errico C, Suzuki Y, Giles JT, Ferrante A, Lippel M, Singh G, Lederer DJ, Christie JD: Adipose Gene Expression Profile Changes with Lung Allograft Reperfusion. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons Jul 2016.

Yehya Nadir, Thomas Neal J, Meyer Nuala J, Christie Jason D, Berg Robert A, Margulies Susan S: Circulating markers of endothelial and alveolar epithelial dysfunction are associated with mortality in pediatric acute respiratory distress syndrome. Intensive care medicine 42(7): 1137-45, Jul 2016.

Monticelli LA, Buck MD, Flamar A, Saenz SA, Tait Wojno ED, Yudanin NA, Osborne LC, Hepworth MR, Tran SV, Rodewald H, Shah H, Cross JR, Diamond JM, Cantu E, Christie JD, Pearce EL, Artis D: Arginase 1 is an innate lymphoid-cell-intrinsic metabolic checkpoint controlling type 2 inflammation. Nature immunology 17(6): 656-65, Jun 2016.

Porteous Mary K, Ky Bonnie, Kirkpatrick James N, Shinohara Russell, Diamond Joshua M, Shah Rupal J, Lee James C, Christie Jason D, Kawut Steven M: Diastolic Dysfunction Increases the Risk of Primary Graft Dysfunction after Lung Transplant. American journal of respiratory and critical care medicine 193(12): 1392-400, Jun 2016.

Diamond JM, Porteous MK, Jackson RL, Wickersham Ny, Rushefski M, Kawut SM, Shah RJ, Cantu E, Lederer DJ, Chatterjee S, Lama VN, Bhorade S, Crespo M, McDyer J, Wille K, Orens J, Weinacker A, Arcasoy S, Shah PD, Wilkes DS, Hage C, Palmer SM, Snyder L, Calfee CS, Ware LB, Christie JD: The relationship between plasma lipid peroxidation products and primary graft dysfunction after lung transplantation is modified by donor smoking and reperfusion hyperoxia. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 35(4): 500-7, Apr 2016.

Cantu E, Suzuki Y, Diamond JM, Ellis J, Tiwari J, Beduhn B, Nellen JR, Shah R, Meyer NJ, Lederer DJ, Kawut SM, Palmer SM, Snyder LD, Hartwig M G, Lama VN, Bhorade S, Crespo M, Demissie E, Wille K, Orens J, Shah PD, Weinacker A, Weill D, Wilkes D, Roe D, Ware L B, Wang F, Feng R, Christie JD: Protein Quantitative Trait Loci Analysis Identifies Genetic Variation in the Innate Immune Regulator TOLLIP in Post-Lung Transplant Primary Graft Dysfunction Risk. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 16(3): 833-40, Mar 2016.

Palakshappa JA, Anderson BJ, Reilly JP, Shashaty MGS, Ueno R, Wu Q, Ittner CAG, Tommasini A, Dunn TG, Charles D, Kazi A, Christie JD, Meyer NJ: Low Plasma Levels of Adiponectin Do Not Explain Acute Respiratory Distress Syndrome Risk: a Prospective Cohort Study of Patients with Severe Sepsis. Critical care (London, England) 20(1): 71, Mar 2016.

Singer JP, Diamond JM, Gries CJ, McDonnough J, Blanc PD, Shah R, Dean MY, Hersh B, Wolters PJ, Tokman S, Arcasoy SM, Ramphal K, Greenland JR, Smith N, Heffernan P, Shah L, Shrestha P, Golden JA, Blumenthal N, Huang D, Sonett J, Hays S, Oyster M, Katz PP, Robbins H, Brown M, Leard LE, Kukreja J, Bacchetta M, Bush E, D'Ovidio F, Rushefski M, Raza K, Christie JD, Lederer DJ: Frailty Phenotypes, Disability, and Outcomes in Adult Candidates for Lung Transplantation. American Journal of Respiratory and Critical Care Medicine 192(11): 1325-34, December 2015

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Last updated: 10/06/2016
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