University of Pennsylvania

Biomedical Graduate Studies
Responsible Conduct of Research (RCR) and Scientific Rigor and Reproducibility (SRR)

Scientific Rigor and Reproducibility (SRR) - Description

Topics covered in Scientific Rigor and Reproducibility (SRR) are scientific premise, rigorous experimental design, consideration of sex and other biological variables, authentication of key biological or chemical resources, and transparency in reporting experimental details.

BGS firmly believes that diligence in maintaining a laboratory notebook is of paramount importance to SRR. The notebook provides a record of primary and secondary data. It should provide as well a record of collaboration, interpretation, and decisions. Importantly, it allows authentication of work by colleagues and outside parties. For all these reasons, training in SRR should always attempt to incorporate training in how to properly manage notebooks. Recommendations can be found the RCR module ‘Acquisition and Management of Data.’