Perelman School of Medicine at the University of Pennsylvania

Penn Institute for Immunology

Publications


Featured Publications

E. John Wherry, PhD

E. John Wherry, PhD
Epigenomic-Guided Mass Cytometry Profiling Reveals Disease-Specific Features of Exhausted CD8 T Cells

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Carl June, MD

Carl June, MD
Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells

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Recent Publications

  1. CD163+ macrophages promote angiogenesis and vascular permeability accompanied by inflammation in atherosclerosis.Guo L, Akahori H, Harari E, Smith SL, Polavarapu R, Karmali V, Otsuka F, Gannon RL, Braumann RE, Dickinson MH, Gupta A, Jenkins AL, Lipinski MJ, Kim J, Chhour P, de Vries PS, Jinnouchi H, Kutys R, Mori H, Kutyna MD, Torii S, Sakamoto A, Choi CU, Cheng Q, Grove ML, Sawan MA, Zhang Y, Cao Y, Kolodgie FD, Cormode DP, Arking DE, Boerwinkle E, Morrison AC, Erdmann J, Sotoodehnia N, Virmani R, Finn AV. J Clin Invest. 2018 Mar 1;128(3):1106-1124. 
  2. Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia. Maude SL, Laetsch TW, Buechner J, Rives S, Boyer M, Bittencourt H, Bader P, Verneris MR, Stefanski HE, Myers GD, Qayed M, De Moerloose B, Hiramatsu H, Schlis K, Davis KL, Martin PL, Nemecek ER, Yanik GA, Peters C, Baruchel A, Boissel N, Mechinaud F, Balduzzi A, Krueger J, June CH, Levine BL, Wood P, Taran T, Leung M, Mueller KT, Zhang Y, Sen K, Lebwohl D, Pulsipher MA, Grupp SA. N Engl J Med. 2018 Feb 1;378(5):439-448.

  3. A PET imaging agent for evaluating PARP-1 expression in ovarian cancer. Makvandi M, Pantel A, Schwartz L, Schubert E, Xu K, Hsieh CJ, Hou C, Kim H, Weng CC, Winters H, Doot R, Farwell MD, Pryma DA, Greenberg RA, Mankoff DA, Simpkins F, Mach RH, Lin LL.  J Clin Invest.2018 Mar 6. pii: 97992.

  4. CAR T cell immunotherapy for human cancer.  June CH, O'Connor RS, Kawalekar OU, Ghassemi S, Milone MC.  Science. 2018 Mar 23;359(6382):1361-1365