Publications
2023
Muneer A, Wang L, Xie L, Zhang F, Wu B, Mei L, Lenarcic EM, Feng EM, Song J, Xiong Y, Yu X, Wang C, Jain K, Strahl BD, Cook JG, Wan YY, Moorman NJ, Song H, Jin J, Chen X. Non-canonical function of histone methyltransferase G9a in the translational regulation of chronic inflammation. Cell Chemical Biology. 2023 December 21
Kumar A, Karuppagounder SS, Chen Y, Corona C, Kawaguchi R, Cheng Y, Balkaya M, Sagdullaev BT, Wen Z, Stuart C, Cho S, Ming GL, Tuvikene J, Timmusk T, Geschwing DH, Ratan RR. 2-Deoxyglucose drives plasticity via an adaptive ER stress-ATF4 pathway and elicits stroke recovery and Alzheimer's resilience. Neuron. 2023 September 20
Jgamadze D, Harary PM, Castellanos M, Blue R, Song H, Ming GL, Chen IH. Protocol for human brain organoid transplantation into a rat visual cortex to model neural repair. Star Protocols. 2023 September 15
Zhou, Y., Song, H. & Ming, Gl. Genetics of human brain development. Nature Reviews Genetics. 2023 July 28
Gracia-Diaz C, Zhou Y, Yang Q, Maroofian R, Espana-Bonilla P, Lee CH, Zhang S, Padilla N, Fueyo R, Waxman EA, Lei S, Otrimski G, Li D, Sheppard SE, Mark P, Harr MH, Hakonarson H, Rodan L, Jackson A, Vasudevan P, Powel C, Mohammed S, Maddirevula S, Alzaidan H, Faqeih EA, Efthymiou S, Turchetti V, Rahman F, Maqbool S, Salpietro V, Ibrahim SH, di Rosa G, Houlden H, Alharbi MN, Al-Sannaa NA, Bauer P, Zifarelli G, Estaras C, Hurst ACE, Thompson ML, Chassevent A, Smith-Hicks CL, de la Cruz X, Holtz AM, Elloumi HZ, Hajianpour MJ, Rieubland C, Braun D, Banka S, Genomic England Research Consortium, French DL, Heller EA, Saade M, Song H, Ming GL, Alkuraya FS, Agrawal PB, Reinberg D, Bhoj EJ, Martínez-Balbás MA, Akizu N. Gain and loss of function variants in EZH1 disrupt neurogenesis and cause dominant and recessive neurodevelopmental disorders. Nature Communications. 2023 July 11.
Salimpour Y, Anderson WS, Dastyeb R, Liu S, Ming GL, Song H, Maragakis NJ, Habela CW. Phase-Amplitude Coupling Detection and Analysis of Human 2-Dimensional Neural Cultures in Multi-well Microelectrode Array in Vitro. BioRxiv 10 July 2023.
Wang X, Sun Y, Zhang DY, Ming GL, Song H. Glioblastoma modeling with 3D organoids: progress and challenges. Oxford Open Neuroscience. 2023 July 6
Zhang F, Yoon KJ, Kim NS, Ming GL, Song H. Cell-autonomous and non-cell-autonomous roles of NKCC1 in regulating neural stem cell quiescence in the hippocampal dentate gyrus. Stem Cell Reports. 2023 July 11.
Sun Y, Wang X, Ming GL, Song H. Brain tumors on slice: A novel platform for personalized therapeutic screening. Cell Reports Medicine. 2023 June 20.
Harary PM, Blue R, Castellanos M, Dedhia M, Hamimi S, Jgamadze D, Rees B, Seshadri N, Singh S, Moreno J, Wolf J, Song H, Ming GL, Chen IH. Human brain organoid transplantation: ethical implications of enhancing specific cerebral functions in small-animal models. Mol. Psychol. 2023 June 6.
Yu H, Usoskin D, Nagi SS, Hu Y, Kupari J, Bouchatta O, Cranfill SL, Su Y, Lv Y, Song H, Ming GL, Prouty S, Seykora J, Wu H, Ma M, Olausson H, Ernfors P, Luo W. Single-Soma Deep RNA sequencing of Human DRG Neurons Reveals Novel Molecular and Cellular Mechanisms Underlying Somatosensation. BioRxiv. 2023 March 18.
Cheng Y, Song H, Ming GL, Weng YL. Epigenetic and epitranscriptomic regulation of axon regeneration. Molecular Psychiatry. 2023 Mar 15.
Hong Y, Yang Q, Song H, Ming GL. Opportunities and limitations for studying neuropsychiatric disorders using patient-derived induced pluripotent stem cells. Molecular Psychiatry. 2023 Feb 13.
Zhang F, Yoon KJ, Zhang DY, Kim NS, Ming GL, Song H. Epitranscriptomic regulation of cortical neurogenesis via Mettl8-dependent mitochondrial tRNA m3C modification. Cell Stem Cell. 2023 Feb 9.
Zhou Y, Su Y, Ming, GL, Song H. Special properties of adult neurogenesis in the human hippocampus: Implications for its clinical applications. Cell Stem Cell. 2023 Feb 5.
Jgamadze D, Lim JT, Zhang Z, Harary PM, Germi J, Mensah-Brown K, Adam CD, Mirzakhalili E, Singh S, Gu JB, Blue R, Dedhia M, Fu M, Jacob F, Qian X, Gagnon K, Sergison M, Fruchet O, Rahaman I, Wang H, Xu F, Xiao R, Contreras D, Wolf JA, Song H, Ming GL, Chen HCI. Structural and functional integration of human forebrain organoids with the injured adult rat visual system. Cell Stem Cell. 2023 Feb 2.
Cable J, Denison MR, Kielian M, Jackson WT, Bartenschlager R, Ahola T, Mukhopadhyay S, Fremont DH, Kuhn RJ, Shannon A, Frazier MN, Yuen KY, Coyne CB, Wolthers KC, Ming GL, Guenther CS, Moshiri J, Best SM, Schoggins JW, Jurado KA, Ebel GD, Schäfer A, Ng LFP, Kikkert M, Sette A, Harris E, Wing PAC, Eggenberger J, Krishnamurthy SR, Mah MG, Meganck RM, Chung D, Maurer-Stroh S, Andino R, Korber B, Perlman S, Shi PY, Bárcena M, Aicher SM, Vu MN, Kenney DJ, Lindenbach BD, Nishida Y, Rénia L, Williams EP. Positive-strand RNA viruses - a Keystone Symposia report. ANNALS of the New York Academy of Sciences. 2023 Jan 25.
Zhang Z, Wang X, Park S, Song H, Ming GL. Development and Application of Brain Region-Specific Organoids for Investigating Psychiatric Disorders. Biological Psychiatry. 2022 Dec 24.
Song EZ, Wang X, Philipson BI, Zhang Q, Thokala R, Zhang L, Assenmacher CA, Binder ZA, Ming GL, O'Rourke DM, Song H, Milone MC. The IAP antagonist birinapant enhances chimeric antigen receptor T cell therapy for glioblastoma by overcoming antigen heterogeneity. Molecular Therapy: Oncolytics. 2022 Nov 15.
Su Y, Zhou Y, Bennett ML, Li S, Carceles-Cordon M, Lu L, Huh S, Jimenez-Cyrus D, Kennedy BC, Kessler SK, Viaene AN, Helbig I, Gu X, Kleinman JE, Hyde TM, Weinberger DR, Nauen DW, Song H, Ming GL. A single-cell transcriptome atlas of glial diversity in the human hippocampus across the postnatal lifespan. Cell Stem Cell. 2022 Nov 3.
Pașca SP, Arlotta P, Bateup HS, Camp JG, Cappello S, Gage FH, Knoblich JA, Kriegstein AR, Lancaster MA, Ming GL, Muotri AR, Park IH, Reiner O, Song H, Studer L, Temple S, Testa G, Treutlein B, Vaccarino FM. A nomenclature consensus for nervous system organoids and assembloids. Nature. 2022 Sept
Li X, Shim S, Hardin KR, Vanaja KG, Song H, Levchenko A, Ming GL, Zheng JQ. Signal amplification in growth cone gradient sensing by a double negative feedback loop among PTEN, PI(3,4,5)P3 and actomysin. Molecular and Cellular Neuroscience. 2022 Aug 31.
Yildirim M, Delepine C, Feldman D, Pham VA, Chou S, Ip J, Nott A, Tsai LH, Ming GL, So PTC, Sur M. Label-free three-photon imaging of intact human cerebral organoids for tracking early events in brain development and deficits in Rett syndrome. eLife. 2022 July 29.
Zhou Y, Su Y, Li S, Kennedy BC, Zhang DY, Bond AM, Sun Y, Jacob F, Lu L, Hu P, Viaene AN, Helbig I, Kessler SK, Lucas T, Salinas RD, Gu X, Chen HI, Wu H, Kleinman JE, Hyde TM, Nauen DW, Weinberger DR, Ming GL, Song H. Molecular landscapes of human hippocampal immature neurons across lifespan. Nature. 2022 July 6.
Fujita Y, Pather SR, Ming GL, Song H. 3D spatial genome organization in the nervous system: From development and plasticity to disease. Neuron. 2022 June 28.
Cheng Y, Medina A, Yao Z, Basu M, Natekar JP, Lang J, Sanchez E, Nkembo MB, Xu C, Qian X, Nguyen PTT, Wen Z, Song H, Ming GL, Kumar M, Brinton MA, Li MMH, Tang H. Intrinsic antiviral immunity of barrier cells revealed by an iPSC-derived blood-brain barrier cellular model. Cell Reports. 2022 May 31.
Koo B, Lee KH, Ming GL, Yoon KJ, Song H. Setting the clock of neural progenitor cells during mammalian corticogenesis. Seminars in Cell and Developmental Biology. 2022 May 26.
Bond AM, Ming GL, Song H. What Is the Relationship Between Hippocampal Neurogenesis Across Different Stages of the Lifespan?. Frontiers in Neuroscience. 2022 May 24.
Yang Q, Hong Y, Zhao T, Song H, Ming GL. What Makes Organoids Good Models of Human Neurogenesis?. Frontiers in Neuroscience. 2022 Apr 14.
Zhang Z, O'Laughlin R, Song H, Ming GL. Patterning of brain organoids derived from human pluripotent stem cells. Current Opinion in Neurobiology. 2022 Apr 8.
GoodSmith D, Kim SH, Puliyadi V, Ming GL, Song H, Knierim JJ, Christian KM. Flexible encoding of objects and space in single cells of the dentate gyrus. Current Biology. 2022 Jan 27.
Ringeling FR, Chakraborty S, Vissers C, Reiman D, Patel AM, Lee KH, Hong A, Park CW, Reska T, Gagneur J, Chang H, Spletter ML, Yoon KJ, Ming GL, Song H, Canzar S. Partitioning RNAs by length improves transcriptome reconstruction from short-read RNA-seq data. Nature Biotechnology. 2022 Jan 10.
Bennett ML, Song H, Ming GL. Microglia modulate neurodevelopment in human neuroimmune organoids. Cell Stem Cell. 2021 Dec 2.
Zhang DY, Ming GL, Song H. PUS7: a targetable epitranscriptomic regulator of glioblastoma growth. Trends in Pharmacological Sciences. 2021 Oct 14.
Fan W, Christian KM, Song H, Ming GL. Applications of Brain Organoids for Infectious Diseases. Journal of Molecular Biology. 2021 Sept 15.
Thokala R, Binder ZA, Yin Y, Zhang L, Zhang JV, Zhang DY, Milone MC, Ming GL, Song H, O'Rourke DM. High-Affinity Chimeric Antigen Receptor With Cross-Reactive scFv to Clinically Relevant EGFR Oncogenic Isoforms. Frontiers in Oncology. 2021 Sept 10.
Ming GL, Song H. Seq-ing out cell types across the isocortex and hippocampal formation. Cell. 2021 June 10.
Kim NS, Ringeling FR, Zhou Y, Nguyen HN, Temme SJ, Lin YT, Eacker S, Dawson VL, Dawson TM, Xiao B, Hsu KS, Canzar S, Li W, Worley P, Christian KM, Yoon KJ, Song H, Ming GL. CYFIP1 Dosages Exhibit Divergent Behavioral Impact via Diametric Regulation of NMDA Receptor Complex Translation in Mouse Models of Psychiatric Disorders. Biological Psychiatry. 2021 May 5.
Huang WK, Wong SZH, Pather SR, Nguyen PTT, Zhang F, Zhang DY, Zhang Z, Lu Lu, Fang W, Chen L, Fernandes A, Su Y, Song H, Ming GL. Generation of hypothalamic arcuate organoids from human induced pluripotent stem cells. Cell Stem Cell. 2021 Apr 28.
Shamim K, Xu M, Hu X, Lee EM, Lu X, Huang R, Shah P, Xu X, Chen CZ, Shen M, Guo H, Chen L, Itkin Z, Eastman RT, Shinn P, Klumpp-Thomas C, Michael S, Simeonov A, Lo DC, Ming GL, Song H, Tang H, Zheng W, Huang W. Application of niclosamide and analogs as small molecule inhibitors of Zika virus and SARS-CoV-2 infection. Bioorganic & Medicinal Chemistry Letters. 2021 Mar 6.
Kim NS, Wen Z, Liu J, Zhou Y, Guo Z, Xu C, Lin YT, Yoon KJ, Park J, Cho M, Kim M, Wang X, Yu H, Sakamuru S, Christian KM, Hsu KS, Xia M, Li W, Ross CA, Margolis RL, Lu XY, Song H, Ming GL. Pharmacological rescue in patient iPSC and mouse models with a rare DISC1 mutation. Nature Communications. 2021 Mar 3.
Song G, Lee EM, Pan J, Xu M, Rho HS, Cheng Y, Whitt N, Yang S, Kouznetsova J, Klumpp-Thomas C, Michael SG, Moore C, Yoon KJ, Christian KM, Simeonov A, Huang W, Xia M, Huang R, Lal-Nag M, Tang H, Zheng W, Qian J, Song H, Ming GL, Zhu H. An Integrated Systems Biology Approach Identifies the Proteasome as A Critical Host Macinery for ZIKV and DENV Replication. Genomics, Proteomics & Bioinformatics. 2021 Feb 18.
Jacob F, Schnoll JG, Song H, Ming GL. Building the brain from scratch: Engineering region-specific brain organoids from human stem cells to study neural development and disease. Current Topics in Developmental Biology. 2021 Feb 18.
Ma T, Wong SZH, Lee B, Ming GL, Song H. Decoding neuronal composition and ontogeny of individual hypothalamic nuclei. Neuron. 2021 Feb 6.
Yang S, Gorshkov K, Lee EM, Xu M, Cheng YS, Sun N, Soheilian F, de Val N, Ming GL, Song H, Tang H, Zheng W. Zika Virus-Induced Neuronal Apoptosis via Increased Mitochondrial Fragmentation. Frontiers in Microbiology. 2020 Dec 23.
Bond AM, Ming GL, Song H. Ontogeny of adult neural stem cells in the mammalian brain. Current Topics in Developmental Biology. 2020 Dec 17.
Bond AM, Berg DA, Lee S, Garcia-Epelboim AS, Adusumilli VS, Ming GL, Song H. Differential Timing and Coordination of Neurogenesis and Astrogenesis in Developing Mouse Hippocampal Subregions. Brain Sciences. 2020 Nov 26.
Jacob F, Ming GL, Song H. Generation and biobanking of patient-derived glioblastoma organoids and their application in CAR T cell testing. Nature Protocols. 2020 Nov 09
Vissers C, Sinha A, Ming GL, Song H. The epitranscriptome in stem cell biology and neural development. Neurobiology of Disease. 2020 Oct 13.
Jacob F, Pather SR, Huang WK, Wong SZH, Zhou H, Zhang F, Cubitt B, Chen CZ, Xu M, Pradhan M, Zhang DY, Zheng W, Bang AG, Song H, de la Torre JC, Ming GL. Human Pluripotent Stem Cell-Derived Neural Cells and Brain Organoids Reveal SARS-CoV-2 Neurotropism Predominates in Choroid Plexus Epithelium. Cell Stem Cell. 2020 Sept 21.
Lu L, Liu X, Huang WK, Giusti-Rodriguez P, Cui J, Zhang S, Xu W, Wen Z, Ma S, Rosen JD, Xu Z, Bartels CF, Kawaguchi R, Ming H, Scacheri PC, Rong Z, Li Y, Sullivan PF, Song H, Ming GL, Li Y, Jin F. Robust Hi-C Maps of Enhancer-Promoter Interactions Reveal the Function of Non-coding Genome in Neural Development and Diseases. Molecular Cell. 2020 Jun 26.
Christian KM, Song H, Ming GL. Using Two- and Three-Dimensional Human iPSC Culture Systems to Model Psychiatric Disorders. Advances in Neurobiology. 2020 Jun 24.
Zhang DY, Song H, Ming GL. Modeling Neurological Disorders Using Brain Organoids. Seminars in Cell and Developmental Biology. 2020 Jun 17.
Jgamadze D, Johnson VE, Wolf JA, Cullen DK, Song H, Ming GL, Smith DH, Chen HI. Modeling Traumatic Brain Injury with Human Brain Organoids. Current Opinion in Biomedical Engineering. 2020 May 11.
Sun G, Chiuppesi F, Chen X, Wang C, Tian E, Nguyen J, Kha M, Trinh D, Zhang H, Marchetto MC, Song H, Ming GL, Gage FH, Diamond DJ, Wussow F, Shi Y. Modeling Human Cytomegalovirus-Induced Microcephaly in Human iPSC-Derived Brain Organoids. Cell Reports. 2020 Apr 21.
Wang XW, Yang SG, Zhang C, Hu MW, Qian J, Ma JJ, Zhang Y, Yang BB, Weng YL, Ming GL, Kosanam AR, Saijilafu, Zhou FQ. Knocking Out Non-muscle Myosin II in Retinal Ganglion Cells Promotes Long-Distance Optic Nerve Regeneration. Cell Reports. 2020 April 21.
Qian X, Su Y, Adam CD, Deutschmann AU, Pather SR, Goldberg EM, Su K, Li S, Lu L, Jacob F, Nguyen PTT, Huh S, Hoke A, Swinford-Jackson SE, Wen Z, Gu X, Pierce RC, Wu H, Briand LA, Chen HI, Wolf JA, Song H, Ming GL. Sliced Human Cortical Organoids for Modeling Distinct Cortical Layer Formation. Cell Stem Cell. 2020 Feb 28.
Habela CW, Yoon KJ, Kim N, Taga A, Bell K, Bergles DE, Maragakis NJ, Ming GL, Song H. Persistent Cyfip1 expression is required to maintain the adult subventricular zone neurogenic niche. Journal of Neuroscience. 2020 Jan 27.
Xu H, Dzhashiashvili Y, Shah A, Kunjamma RB, Weng YL, Elbaz B, Fei Q, Jones JS, Li YI, Zhuang X, Ming GL, He C, Popko B. m6A mRNA Methylation Is Essential for Oligodendrocyte Maturation and CNS Myelination. Neuron. 2020 Jan 22.
Jacob F, Salinas RD, Zhang DY, Nguyen PTT, Schnoll JG, Wong SZH, Thokala R, Sheikh S, Saxena D, Prokop S, Liu DA, Qian X, Petrov D, Lucas T, Chen HI, Dorsey JF, Christian KM, Binder ZA, Nasrallah M, Brem S, O'Rourke DM, Ming GL, Song H. A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity. Cell. 2019 Dec 23.
Makhlin I, Salinas RD, Zhang D, Jacob F, Ming FL, Song H, Saxena D, Dorsey JF, Nasrallah MP, Morrissette JJ, Binder ZA, O'Rourke DM, Desai AS, Brem S, Bagley SJ. Clinical activity of the EGFR tyrosine kinase inhibitor osimertinib in EGFR-mutant glioblastoma. CNS Oncology. 2019 Nov 1.
Christian KM, Ming GL, Song H. Adult neurogenesis and the dentate gyrus: Predicting function from form. Behavioural Brain Research. 2019 Nov 10.
Chen HI, Wolf JA, Blue R, Song MM, Moreno JD, Ming GL, Song H. Transplantation of Human Brain Organoids: Revisiting the Sciences and Ethics of Brain Chimeras. Cell Stem Cell. 2019 Oct 3.
Schnoll JG, Temsamrit B, Zhang D, Song H, Ming GL, Christian KM. Evaluating Neurodevelopmental Consequences of Perinatal Exposure to Antiretroviral Drugs: Current Challenges and New Approaches. Journal of Neuroimmune Pharmacology. 2019 Sep 11.
Wang X, Ye F, Wen Z, Guo Z, Yu C, Huang WK, Rojas Ringeling F, Su Y, Zheng W, Zhou G, Christian KM, Song H, Zhang M, Ming GL. Structural interaction between DISC1 and ATF4 underlying transcriptional and synaptic dysregulation in an iPSC model of mental disorders. Molecular Psychiatry. 2019 Aug 23.
Kang E, Song J, Lin Y, Park J, Lee JH, Hussani Q, Gu Y, Ge S, Li W, Hsu KS, Berninger B, Christian KM, Song H, Ming GL. Interplay between a Mental Disorder Risk Gene and Developmental Polarity Switch of GABA Action Leads to Excitation-Inhibition Imbalance. Cell Reports. 2019 Aug 6.
Hammack C, Ogden SC, Madden JC Jr, Medina A, Xu C, Phillips E, Son Y, Cone A, Giovinazzi S, Didier RA, Gilbert DM, Song H, Ming G, Wen Z, Bringon MA, Gunjan A, Tang H. Zika virus infection induces DNA damage response in human neural progenitors that enhances viral replication. Journal of Virology. 2019 Aug 2.
Song M, Yang X, Ren X, Maliskova L, Li B, Jones IR, Wang C, Jacob F, Wu K, Traglia M, Tam TW, Jamieson K, Lu SY, Ming GL, Li Y, Yao J, Weiss La, Dixon JR, Judge LM, Conklin BR, Song H, Gan L, Shen Y. Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes. Nature Genetics. 2019 Aug.
Edens BM, Vissers C, Su J, Arumugam S, Xu Z, Shi H, Miller N, Rojas Ringeling F, Ming GL, He C, Song H, Ma YC. FMRP Modulates Neural Differentiation through m6A-Dependent mRNA Nuclear Export. Cell Reports. 2019 July 23.
Christian KM, Song H, Ming GL. Pathophysiology and Mechanisms of Zika Virus Infection in the Nervous System. Annual Review of Neuroscience. 2019 July 8.
Zhao T, Hong Y, Ming GL, Song H. Loss of chromatin Dpy30 compromises proliferation and differentiation of postnatal neural stem cells. Journal of Molecular Cell Biology. 2019 May 24.
Bentea E, Depasquale EAK, O'Donovan SM, Sullivan CR, Simmons M, Meador-Woodruff JH, Zhou Y, Xu C, Bai B, Peng J, Song H, Ming GL, Meller J, Wen Z, McCullumsmith RE. Kinase network dysregulation in a human induced pluripotent stem cell model of DISC1 schizophrenia. Molecular Omics. 2019 May 20.
Qian X, Song H, Ming GL. Brain organoids: advances, applications, and challenges. Development. 2019 Apr 16.
Berg DA, Su Y, Jimenez-Cyrus D, Patel A, Huang N, Morizet D, Lee S, Shah R, Ringeling FR, Epstein JA, Wu QF, Canzar S, Ming GL, Song H, Bond AM. A Common Embryonic Origin of Stem Cells Drives Developmental and Adult Neurogenesis. Cell. 2019 Mar 28.
Vissers C, Ming GL, Song H. Nanoparticle technology and stem cell therapy team up against neurodegenerative disorders. Advanced Drug Delivery Reviews. 2019 Feb 21.
Shi H, Zhang X, Weng YL, Lu Z, Liu Y, Lu Z, Li J, Hao P, Zhang Y, Zhang F, Wu Y, Delgado JY, Su Y, Patel MJ, Cao X, Shen B, Huang X, Ming GL, Zhuang X, Song H, He C, Zhou T. m6A facilitates hippocampus-dependent learning and memory through YTHDF1. Nature. 2018 Oct 31.
Zhou Y, Bond AM, Shade JE, Zhu Y, Davis CO, Su Y, Yoon KJ, Phan AT, Chen WJ, Oh JH, Marsh-Armstrong N, Atabai K, Ming GL, Song H. Autocrine Mfge8 Signaling Prevents Developmental Exhaustion of the Adult Neural Stem Cell Pool. Cell Stem Cell. 2018 Aug 21.
Chen HI, Song H, Ming, GL. Applications of human brain organoids to clinical problems. Developmental Dynamics. 2018 Aug 09.
Yoon KJ, Ming GL, Song H. Epitranscriptomics in the Adult Mammalian Brain: Dynamic Changes Regulate Behavior. Neuron. 2018 Jul 25.
Yang S, Xu M, Lee EM, et al. Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry. Cell Discovery. 2018 June.
Wong SZH, Scott EP, Mu W, Guo X, Borgenheimer E, Freeman M, Ming GL, Wu QF, Song H, Nakagawa Y. In vivo clonal analysis reveals spatiotemporal regulation of thalamic nucleogenesis. PLOS Biology. 2018 Apr 23.
Yoon KJ, Vissers C, Ming GL, Song H. Epigenetics and epitranscriptomics in temporal patterning of cortical neural progenitor competence. Journal of Cell Biology. 2018 Apr 17.
Yoon KJ, Ming GL, Song H. Coupling Neurogenesis to Circuit Formation. Cell. 2018 Apr 5.
Christian KM, Song H, Ming GL. A previously undetected pathology of Zika virus infection. Nature Medicine. 2018 Mar 6.
Berg DA, Bond AM, Ming GL, Song H. Radial glial cells in the adult dentate gyrus: what are they and where do they come from? F1000 Research. 2018 Mar 5.
Qian X, Jacob F, Song MM, Nguyen HN, Song H, Ming GL. Generation of human brain region-specific organoids using a minaturized spinning bioreactor. Nature Protocol. 2018 Mar.
Wang X, Christian KM, Song H, Ming GL. Synaptic dysfunction in complex psychiatric disorders: from genetics to mechanisms. Genome Medicine. 2018 Jan 31.
Weng YL, Wang X, An R, Cassin J, Vissers C, Liu Y, Liu Y, Xu T, Wang X, Wong S, Joseph J, Dore LC, Dong Q, Zheng W, Jin P, Wu H, Shen B, Zhuang X, He C, Liu K, Song H, Ming GL. Epitranscriptomic m6A Regulation of Axon Regeneration in the Adult Mammalian Nervous System Neuron. 2018 Jan 17.
Ye F, Kang E, Yu C, Qian X, Jacob F, Yu C, Mao M, Poon M.Y.C, Kim J, Song, H, Ming GL, Zhang M. DISC1 Regulates Neurogenesis via Modulating Kinetochore Attachment of Ndel1/Nde1 during Mitosis. Neuron. 2017 Dec 6.
C Vissers, Ming GL, Song, H. Stem cells take the stairs. Journal of Biological Chemistry. 2017 Dec 1.
Song G, Rho HS, Pan J, Ramos P, Yoon KJ, Medina FA, Lee EM, Eichinger DJ, Ming GL, Munoz-Jordan JL, Tang H, Pino I, Song H, Qian J, Zhu H. Multiplexed biomarker panels discriminate Zika and Dengue virus infection in humans. Molecular & Cellular Proteomics. 2017 Nov 15.
Yoon KJ, Rojas Ringeling F, Vissers C, Jacob F, Pokrass M, Jimenez-Cyrus D, Su Y, Kim NS, Zhu Y, Zheng L, Kim S, Wang X, Dore L, Jin P, Regot S, Zhuang X, Canzar S, He C, Ming GL, Song H. Temporal Control of Mammalian Cortical Neurogenesis by m6A Methylation. Cell. 2017 Sep 28.
Yoon KJ, Song G, Qian X, Pan J, Xu D, Rho HS, Kim NS, Habela C, Zheng L, Jacob F, Zhang F, Lee EM, Huang WK, Ringeling FR, Vissers C, Li C, Yuan L, Kang K, Kim S, Yeo J, Cheng Y, Liu S, Wen Z, Qin CF, Wu Q, Christian KM, Tang H, Jin P, Xu Z, Qian J, Zhu H, Song H, Ming GL. Zika-Virus-Encoded NS2A Disrupts Mammalian Cortical Neurogenesis by Degrading Adherens Junction Proteins. Cell Stem Cell. 2017 Aug 16. [Epub ahead of print] PubMed PMID: 28826723.
Oh Y, Zhang F, Wang Y, Lee EM, Choi IY, Lim H, Mirakhori F, Li R, Huang L, Xu T, Wu H, Li C, Qin CF, Wen Z, Wu QF, Tang H, Xu Z, Jin P, Song H, Ming GL, Lee G. Zika virus directly infects peripheral neurons and induces cell death. Nature neuroscience. 2017 Jul; PubMed [journal] PMID: 28758997
Kang E, Jiang D, Ryu YK, Lim S, Kwak M, Gray CD, Xu M, Choi JH, Junn S, Kim J, Xu J, Schaefer M, Johns RA, Song H, Ming GL, Mintz CD. Early postnatal exposure to isoflurane causes cognitive deficits and disrupts development of newborn hippocampal neurons via activation of the mTOR pathway. PLoS Biol. 2017 Jul 6;15(7):e2001246. eCollection 2017 Jul. PubMed PMID: 28683067; PubMed Central PMCID: PMC5500005.
Ming GL, Song H, Tang H. Racing to Uncover the Link between Zika Virus and Microcephaly. Cell Stem Cell. 2017 Jun 1;20(6):749-753. PubMed PMID: 28575689.
Wan J, Su Y, Song Q, Tung B, Oyinlade O, Liu S, Ying M, Ming GL, Song H, Qian J, Zhu H, Xia S. Methylated cis-regulatory elements mediate KLF4-dependent gene transactivation and cell migration. Elife. 2017 May 29;6. PubMed PMID: 28553926; PubMed Central PMCID: PMC5466421.
Wen Z, Song H, Ming GL. How does Zika virus cause microcephaly? Genes Dev. 2017 May 1;31(9):849-861. Review. PubMed PMID: 28566536; PubMed Central PMCID: PMC5458753.
Li X, Tzeng SY, Zamboni CG, Koliatsos VE, Ming GL, Green JJ, Mao HQ. Enhancing oligodendrocyte differentiation by transient transcription activation via DNA nanoparticle-mediated transfection. Acta Biomater. 2017 May;54:249-258. Epub 2017 Mar 23. PubMed PMID: 28344151; PubMed Central PMCID: PMC5485910.
Weng YL, An R, Cassin J, Joesph J, Mi R, Wang C, Zhong C, Jin SG, Pfeifer GP, Bellacosa A, Dong X, Hoke A, He Z, Song H, Ming GL. An Intrinsic Epigenetic Barrier for Functional Axon Regeneration. Neuron. 2017 Apr 19; 94(2):337-346. PMID: 28426967.
Qian K, Huang H, Peterson A, Hu B, Maragakis NJ, Ming GL, Chen H, Zhang SC. Sporadic ALS Astrocytes Induce Neuronal Degeneration In Vivo. Stem Cell Reports. 2017 Apr 11;8(4):843-855. Epub 2017 Mar 30. PubMed PMID: 28366455; PubMed Central PMCID: PMC5390239.
Beckervordersandforth R, Ebert B, Schäffner I, Moss J, Fiebig C, Shin J, Moore DL, Ghosh L, Trinchero MF, Stockburger C, Friedland K, Steib K, von Wittgenstein J, Keiner S, Redecker C, Hölter SM, Xiang W, Wurst W, Jagasia R, Schinder AF, Ming GL, Toni N, Jessberger S, Song H, Lie DC. Role of Mitochondrial Metabolism in the Control of Early Lineage Progression and Aging Phenotypes in Adult Hippocampal Neurogenesis. Neuron. 2017 Mar 22;93(6):1518. PubMed PMID: 28334613.
Qian X, Nguyen HN, Jacob F, Song H, Ming GL. Using brain organoids to understand Zika virus-induced microcephaly. Development. 2017 Mar 15;144(6):952-957. PubMed PMID: 28292840; PubMed Central PMCID: PMC5358105.
Su Y, Shin J, Zhong C, Wang S, Roychowdhury P, Lim J, Kim D, Ming GL, Song H. Neuronal activity modifies the chromatin accessibility landscape in the adult brain. Nature neuroscience. 2017 Mar; 20(3):476-483. PMC5325677
Ming GL, Tang H, Song H. Advances in Zika Virus Research: Stem Cell Models, Challenges, and Opportunities. Cell stem cell. 2016 Dec 1; 19(6):690-702. PMC5218815
Pamies D, Barreras P, Block K, Makri G, Kumar A, Wiersma D, Smirnova L, Zang C, Bressler J, Christian KM, Harris G, Ming GL, Berlinicke CJ, Kyro K, Song H, Pardo CA, Hartung T, Hogberg HT. A human brain microphysiological system derived from induced pluripotent stem cells to study neurological diseases and toxicity. ALTEX. 2017;34(3):362-376. Epub 2016 Nov 24. PubMed PMID: 27883356.
Zhang F, Hammack C, Ogden SC, Cheng Y, Lee EM, Wen Z, Qian X, Nguyen HN, Li Y, Yao B, Xu M, Xu T, Chen L, Wang Z, Feng H, Huang WK, Yoon KJ, Shan C, Huang L, Qin Z, Christian KM, Shi PY, Xu M, Xia M, Zheng W, Wu H, Song H, Tang H, Ming GL, Jin P. Molecular signatures associated with ZIKV exposure in human cortical neural progenitors. Nucleic Acids Res. 2016 Oct 14;44(18):8610-8620. Epub 2016 Aug 31. PubMed PMID: 27580721; PubMed Central PMCID: PMC5063002.
Wang Y, An R, Umanah GK, Park H, Nambiar K, Eacker SM, Kim B, Bao L, Harraz MM, Chang C, Chen R, Wang JE, Kam TI, Jeong JS, Xie Z, Neifert S, Qian J, Andrabi SA, Blackshaw S, Zhu H, Song H, Ming GL, Dawson VL, Dawson TM. A nuclease that mediates cell death induced by DNA damage and poly(ADP-ribose) polymerase-1. Science. 2016 Oct 7;354(6308). PubMed PMID: 27846469; PubMed Central PMCID: PMC5134926.
Xu M, Lee EM, Wen Z, Cheng Y, Huang WK, Qian X, Tcw J, Kouznetsova J, Ogden SC, Hammack C, Jacob F, Nguyen HN, Itkin M, Hanna C, Shinn P, Allen C, Michael SG, Simeonov A, Huang W, Christian KM, Goate A, Brennand KJ, Huang R, Xia M, Ming GL, Zheng W, Song H, Tang H. Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen. Nat Med. 2016 Oct;22(10):1101-1107. Epub 2016 Aug 29. PubMed PMID: 27571349; PubMed Central PMCID: PMC5386783.
Weng YL, Joseph, J, An R, Song H, Ming GL. Epigenetic regulation of axonal regenerative capacity. Epigenomics. 2016 Sep 19; 8(10):1429-1442. PMID 27642866
Kang E, Wen Z, Song H, Christian KM, Ming GL. Adult Neurogenesis and Psychiatric Disorders. Cold Spring Harb Perspect Biol. 2016 Sep 1;8(9). Review. PubMed PMID: 26801682.
Yao B, Christian KM, He C, Jin P, Ming GL, Song H. Epigenetic mechanisms in neurogenesis. Nat Rev Neurosci. 2016 Sep;17(9):537-49. Epub 2016 Jun 23. Review. PubMed PMID: 27334043.
Song J, Olsen RH, Sun J, Ming GL, Song H. Neuronal Circuitry Mechanisms Regulating Adult Mammalian Neurogenesis. Cold Spring Harb Perspect Biol. 2016 Aug 1;8(8). Review. PubMed PMID: 27143698.
Sailor KA, Valley MT, Wiechert MT, Riecke H, Sun GJ, Adams W, Dennis JC, Sharafi S, Ming GL, Song H, Lledo PM. Persistent Structural Plasticity Optimizes Sensory Information Processing in the Olfactory Bulb. Neuron. 2016 Jul 20; 91(2):384-96.
Nguyen HN, Qian X, Song H, Ming GL. Neural stem cells attacked by Zika virus. Cell Res. 2016 Jul;26(7):753-4. Epub 2016 Jun 10. PubMed PMID: 27283801; PubMed Central PMCID: PMC5129882.
Zhang H, Kang E, Wang Y, Yang C, Yu H, Wang Q, Chen Z, Zhang C, Christian KM, Song H, Ming GL, Xu Z. Brain-specific Crmp2 deletion leads to neuronal development deficits and behavioural impairments in mice. Nat Commun. 2016 Jun 1;7. PubMed PMID: 27249678; PubMed Central PMCID: PMC4895353.
Habela CW, Song H, Ming GL. Modeling synaptogenesis in schizophrenia and autism using human iPSC derived neurons. Mol Cell Neurosci. 2016 Jun;73:52-62. Epub 2015 Dec 2. Review. PubMed PMID: 26655799.
Qian X, Nguyen HN, Song MM, Hadiono C, Ogden SC, Hammack C, Yao B, Hamersky GR, Jacob F, Zhong C, Yoon KJ, Jeang W, Lin L, Li Y, Thakor J, Berg DA, Zhang C, Kang E, Chickering M, Nauen D, Ho CY, Wen Z, Christian KM, Shi PY, Maher BJ, Wu H, Jin P, Tang H, Song H, Ming GL. Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure. Cell. 2016 May 19; 165(5):1238-54. PMC4900885
Tang H, Hammack C, Ogden SC, Wen Z, Qian X, Li Y, Yao B, Shin J, Zhang F, Lee EM, Christian KM, Didier RA, Jin P, Song H, Ming GL. Zika Virus Infects Human Cortical Neural Progenitors and Attenuates Their Growth. Cell stem cell. 2016 May 5; 18(5):587-90. PMC5299540
Bonaguidi MA, Stadel RP, Berg DA, Sun J, Ming GL, Song H. Diversity of Neural Precursors in the Adult Mammalian Brain. Cold Spring Harb Perspect Biol. 2016 Apr 1;8(4):a018838. Review. PubMed PMID: 26988967.
Gebara E, Bonaguidi MA, Beckervordersandforth R, Sultan S, Udry F, Gijs PJ, Lie DC, Ming GL, Song H, Toni N. Heterogeneity of Radial Glia-Like Cells in the Adult Hippocampus. Stem cells (Dayton, Ohio). 2016 Apr; 34(4):997-1010. PMC5340291
Wen Z, Song H, Ming GL. Patient iPSCs: a new discovery tool for Smith-Lemli-Opitz syndrome. Nat Med. 2016 Apr;22(4):343-4. PubMed PMID: 27050588.
Murai K, Sun G, Ye P, Tian E, Yang S, Cui Q, Sun G, Trinh D, Sun O, Hong T, Wen Z, Kalkum M, Riggs AD, Song H, Ming GL, Shi Y. The TLX-miR-219 cascade regulates neural stem cell proliferation in neurodevelopment and schizophrenia iPSC model. Nat Commun. 2016 Mar 11;7:10965. PubMed PMID: 26965827; PubMed Central PMCID: PMC4793043.
Karuppagounder SS, Alim I, Khim SJ, Bourassa MW, Sleiman SF, John R, Thinnes CC, Yeh TL, Demetriades M, Neitemeier S, Cruz D, Gazaryan I, Killilea DW, Morgenstern L, Xi G, Keep RF, Schallert T, Tappero RV, Zhong J, Cho S, Maxfield FR, Holman TR, Culmsee C, Fong GH, Su Y, Ming GL, Song H, Cave JW, Schofield CJ, Colbourne F, Coppola G, Ratan RR. Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models. Sci Transl Med. 2016 Mar 2;8(328):328ra29. PubMed PMID: 26936506; PubMed Central PMCID: PMC5341138.
Wen Z, Christian KM, Song H, Ming GL. Modeling psychiatric disorders with patient-derived iPSCs. Current opinion in neurobiology. 2016 Feb; 36:118-27. PMC4738077
Zeng Y, Yao B, Shin J, Lin L, Kim N, Song Q, Liu S, Su Y, Guo JU, Huang L, Wan J, Wu H, Qian J, Cheng X, Zhu H, Ming GL, Jin P, Song H. Lin28A Binds Active Promoters and Recruits Tet1 to Regulate Gene Expression. Molecular cell. 2016 Jan 7; 61(1):153-60. PMC4779955
Kang E, Kim JY, Liu CY, Xiao B, Chen PY, Christian KM, Worley PF, Song H, Ming GL. Rheb1 mediates DISC1-dependent regulation of new neuron development in the adult hippocampus. Neurogenesis (Austin). 2015 Nov 10;2(1):e1081715. eCollection 2015. PubMed PMID: 27606328; PubMed Central PMCID: PMC4973590.
Sun GJ, Zhou Y, Ito S, Bonaguidi MA, Stein-O'Brien G, Kawasaki NK, Modak N, Zhu Y, Ming GL, Song H. Latent tri-lineage potential of adult hippocampal neural stem cells revealed by Nf1 inactivation. Nature neuroscience. 2015 Nov 2; 18(12):1722-4. PMC4661096
Bond AM, Ming GL, Song H. Adult Mammalian Neural Stem Cells and Neurogenesis: Five Decades Later. Cell stem cell. 2015 Oct 1; 17(4):385-95. PMC4683085
Sun J, Bonaguidi MA, Jun H, Guo JU, Sun GJ, Will B, Yang Z, Jang MH, Song H, Ming GL, Christian KM. A septo-temporal molecular gradient of sfrp3 in the dentate gyrus differentially regulates quiescent adult hippocampal neural stem cell activation. Mol Brain. 2015 Sep 4;8:52. PubMed PMID: 26337530; PubMed Central PMCID: PMC4559945.
Shin J, Berg DA, Zhu Y, Shin JY, Song J, Bonaguidi MA, Enikolopov G, Nauen DW, Christian KM, Ming GL, Song H. Single-Cell RNA-Seq with Waterfall Reveals Molecular Cascades underlying Adult Neurogenesis. Cell Stem Cell. 2015 Sep 3;17(3):360-72. Epub 2015 Aug 20. PubMed PMID: 26299571.
Su Y, Ming GL, Song H. DNA damage and repair regulate neuronal gene expression. Cell research. 2015 Sep; 25(9):993-4. PMC4559811
Sun GJ, Zhou Y, Stadel RP, Moss J, Yong JH, Ito S, Kawasaki NK, Phan AT, Oh JH, Modak N, Reed RR, Toni N, Song H, Ming GL. Tangential migration of neuronal precursors of glutamatergic neurons in the adult mammalian brain. Proceedings of the National Academy of Sciences of the United States of America. 2015 Jul 28; 112(30):9484-9. PMC4522763
Lee H, Kang E, GoodSmith D, Yoon DY, Song H, Knierim JJ, Ming GL, Christian KM. DISC1-mediated dysregulation of adult hippocampal neurogenesis in rats. Frontiers in systems neuroscience. 2015 Jun 25; 9:93.
Yu H, Su Y, Shin J, Zhong C, Guo JU, Weng YL, Gao F, Geschwind DH, Coppola G, Ming GL, Song H. Tet3 regulates synaptic transmission and homeostatic plasticity via DNA oxidation and repair. Nature neuroscience. 2015 Jun; 18(6):836-43. PMC4446239
Ming GL. Neuroepigenetics: Introduction to the special issue on epigenetics in neurodevelopment and neurological diseases. Experimental neurology. 2015 Jun; 268:1-2.
Shin J, Ming GL, Song H. Seeking a roadmap toward neuroepigenetics. Neuron. 2015 Apr 8; 86(1):12-5.
Feng J, Shao N, Szulwach KE, Vialou V, Huynh J, Zhong C, Le T, Ferguson D, Cahill ME, Li Y, Koo JW, Ribeiro E, Labonte B, Laitman BM, Estey D, Stockman V, Kennedy P, Couroussé T, Mensah I, Turecki G, Faull KF, Ming GL, Song H, Fan G, Casaccia P, Shen L, Jin P, Nestler EJ. Role of Tet1 and 5-hydroxymethylcytosine in cocaine action. Nature neuroscience. 2015 Apr; 18(4):536-44. PMC4617315
Ma D, Yoon SI, Yang CH, Marcy G, Zhao N, Leong WY, Ganapathy V, Han J, Van Dongen AM, Hsu KS, Ming GL, Augustine GJ, Goh EL. Rescue of Methyl-CpG Binding Protein 2 Dysfunction-induced Defects in Newborn Neurons by Pentobarbital. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2015 Apr; 12(2):477-90. PMC4404443
Shin J, Ming GL, Song H. Molecular toggle switch of histone demethylase LSD1. Molecular cell. 2015 Mar 19; 57(6):949-50.
Huang W, Ming GL, Song H. Experience matters: enrichment remodels synaptic inputs to adult-born neurons. Neuron. 2015 Feb 18; 85(4):659-61.
Griesi-Oliveira K, Acab A, Gupta AR, Sunaga DY, Chailangkarn T, Nicol X, Nunez Y, Walker MF, Murdoch JD, Sanders SJ, Fernandez TV, Ji W, Lifton RP, Vadasz E, Dietrich A, Pradhan D, Song H, Ming GL, Gu X, Haddad G, Marchetto MC, Spitzer N, Passos-Bueno MR, State MW, Muotri AR. Modeling non-syndromic autism and the impact of TRPC6 disruption in human neurons. Molecular psychiatry. 2015; 20(11):1350-65. PMC4427554
Wen Z, Nguyen HN, Guo Z, Lalli MA, Wang X, Su Y, Kim NS, Yoon KJ, Shin J, Zhang C, Makri G, Nauen D, Yu H, Guzman E, Chiang CH, Yoritomo N, Kaibuchi K, Zou J, Christian KM, Cheng L, Ross CA, Margolis RL, Chen G, Kosik KS, Song H, Ming GL. Synaptic dysregulation in a human iPS cell model of mental disorders. Nature. 2014 Nov 20; 515(7527):414-8. PMC4501856
Shin J, Ming GL, Song H. Decoding neural transcriptomes and epigenomes via high-throughput sequencing. Nature neuroscience. 2014 Oct 28; 17(11):1463-75.
Duan Y, Wang SH, Song J, Mironova Y, Ming GL, Kolodkin AL, Giger RJ. Semaphorin 5A inhibits synaptogenesis in early postnatal- and adult-born hippocampal dentate granule cells. eLife. 2014 Oct 14; 3. PMC4236683
Shin J, Ming GL, Song H. DNA modifications in the mammalian brain. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 2014 Sep 26; 369(1652). PMC4142033
Yoon KJ, Nguyen HN, Ursini G, Zhang F, Kim NS, Wen Z, Makri G, Nauen D, Shin JH, Park Y, Chung R, Pekle E, Zhang C, Towe M, Hussaini SM, Lee Y, Rujescu D, St Clair D, Kleinman JE, Hyde TM, Krauss G, Christian KM, Rapoport JL, Weinberger DR, Song H, Ming GL. Modeling a genetic risk for schizophrenia in iPSCs and mice reveals neural stem cell deficits associated with adherens junctions and polarity. Cell stem cell. 2014 Jul 3; 15(1):79-91. PMC4237009
Christian KM, Song H, Ming GL. Functions and dysfunctions of adult hippocampal neurogenesis. Annual review of neuroscience. 2014 May 29; 37:243-62.
Song H, Ming GL. Reprogram to pluripotency: a new logic and a chemical cocktail. Natl Sci Rev. 2014 Mar;1(1):6-7. Epub 2013 Dec 6. PubMed PMID: 26998393; PubMed Central PMCID: PMC4798243.
Guo JU, Szulwach KE, Su Y, Li Y, Yao B, Xu Z, Shin JH, Xie B, Gao Y, Ming GL, Jin P, Song H. Genome-wide antagonism between 5-hydroxymethylcytosine and DNA methylation in the adult mouse brain. Frontiers in biology. 2014 Feb; 9(1):66-74. PMC4284063
Guo JU, Su Y, Shin JH, Shin J, Li H, Xie B, Zhong C, Hu S, Le T, Fan G, Zhu H, Chang Q, Gao Y, Ming GL, Song H. Distribution, recognition and regulation of non-CpG methylation in the adult mammalian brain. Nature neuroscience. 2014 Feb; 17(2):215-22. PMC3970219
2013
Shim S, Zheng JQ, Ming GL. A critical role for STIM1 in filopodial calcium entry and axon guidance. Molecular brain. 2013 Dec 1; 6:51. PMC3907062
Song J, Sun J, Moss J, Wen Z, Sun GJ, Hsu D, Zhong C, Davoudi H, Christian KM, Toni N, Ming GL, Song H. Parvalbumin interneurons mediate neuronal circuitry-neurogenesis coupling in the adult hippocampus. Nature neuroscience. 2013 Dec; 16(12):1728-30. PMC4096812
Weng YL, An R, Shin J, Song H, Ming GL. DNA modifications and neurological disorders. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2013 Oct; 10(4):556-67. PMC3805853
Kaas GA, Zhong C, Eason DE, Ross DL, Vachhani RV, Ming GL, King JR, Song H, Sweatt JD. TET1 controls CNS 5-methylcytosine hydroxylation, active DNA demethylation, gene transcription, and memory formation. Neuron. 2013 Sep 18; 79(6):1086-93. PMC3816951
Hu S, Wan J, Su Y, Song Q, Zeng Y, Nguyen HN, Shin J, Cox E, Rho HS, Woodard C, Xia S, Liu S, Lyu H, Ming GL, Wade H, Song H, Qian J, Zhu H. DNA methylation presents distinct binding sites for human transcription factors. eLife. 2013 Sep 3; 2:e00726. PMC3762332
Sun GJ, Sailor KA, Mahmood QA, Chavali N, Christian KM, Song H, Ming GL. Seamless reconstruction of intact adult-born neurons by serial end-block imaging reveals complex axonal guidance and development in the adult hippocampus. The Journal of neuroscience: the official journal of the Society for Neuroscience. 2013 Jul 10; 33(28):11400-11. PMC3724551
Callicott JH, Feighery EL, Mattay VS, White MG, Chen Q, Baranger DA, Berman KF, Lu B, Song H, Ming GL, Weinberger DR. DISC1 and SLC12A2 interaction affects human hippocampal function and connectivity. The Journal of clinical investigation. 2013 Jul; 123(7):2961-4. PMC3999052
Ng T, Ryu JR, Sohn JH, Tan T, Song H, Ming GL, Goh EL. Class 3 semaphorin mediates dendrite growth in adult newborn neurons through Cdk5/FAK pathway. PloS one. 2013 Jun 10; 8(6):e65572. PMC3677868
Shin J, Ming GL, Song H. By hook or by crook: multifaceted DNA-binding properties of MeCP2. Cell. 2013 Feb 28; 152(5):940-2. PMC4119793
Zhou M, Li W, Huang S, Song J, Kim JY, Tian X, Kang E, Sano Y, Liu C, Balaji J, Wu S, Zhou Y, Zhou Y, Parivash SN, Ehninger D, He L, Song H, Ming GL, Silva AJ. mTOR Inhibition ameliorates cognitive and affective deficits caused by Disc1 knockdown in adult-born dentate granule neurons. Neuron. 2013 Feb 20; 77(4):647-54. PMC3586374
Jang MH, Bonaguidi MA, Kitabatake Y, Sun J, Song J, Kang E, Jun H, Zhong C, Su Y, Guo JU, Wang MX, Sailor KA, Kim JY, Gao Y, Christian KM, Ming GL, Song H. Secreted frizzled-related protein 3 regulates activity-dependent adult hippocampal neurogenesis. Cell stem cell. 2013 Feb 7; 12(2):215-23. PMC3569732
2012
Song J, Christian KM, Ming GL, Song H. Life or death: developing cortical interneurons make their own decision. The EMBO journal. 2012 Nov 28; 31(23):4373-4. PMC3512393
Bonaguidi MA, Song J, Ming GL, Song H. A unifying hypothesis on mammalian neural stem cell properties in the adult hippocampus. Current opinion in neurobiology. 2012 Oct; 22(5):754-61. PMC3415562
Song J, Zhong C, Bonaguidi MA, Sun GJ, Hsu D, Gu Y, Meletis K, Huang ZJ, Ge S, Enikolopov G, Deisseroth K, Luscher B, Christian KM, Ming GL, Song H. Neuronal circuitry mechanism regulating adult quiescent neural stem-cell fate decision. Nature. 2012 Sep 6; 489(7414):150-4. PMC3438284
Song J, Christian KM, Ming GL, Song H. Modification of hippocampal circuitry by adult neurogenesis. Developmental neurobiology. 2012 Jul; 72(7):1032-43. PMC3710549
Juopperi TA, Kim WR, Chiang CH, Yu H, Margolis RL, Ross CA, Ming GL, Song H. Astrocytes generated from patient induced pluripotent stem cells recapitulate features of Huntington's disease patient cells. Molecular brain. 2012 May 21; 5:17. PMC3506453
Kim JY, Liu CY, Zhang F, Duan X, Wen Z, Song J, Feighery E, Lu B, Rujescu D, St Clair D, Christian K, Callicott JH, Weinberger DR, Song H, Ming GL. Interplay between DISC1 and GABA signaling regulates neurogenesis in mice and risk for schizophrenia. Cell. 2012 Mar 2; 148(5):1051-64. PMC3294278
Kim WR, Christian K, Ming GL, Song H. Time-dependent involvement of adult-born dentate granule cells in behavior. Behavioural brain research. 2012; 227(2):470-9.
2011
Kang E, Burdick KE, Kim JY, Duan X, Guo JU, Sailor KA, Jung DE, Ganesan S, Choi S, Pradhan D, Lu B, Avramopoulos D, Christian K, Malhotra AK, Song H, Ming GL. Interaction between FEZ1 and DISC1 in regulation of neuronal development and risk for schizophrenia. Neuron. 2011 Nov 17; 72(4):559-71. PMC3222865
Ming GL, Brüstle O, Muotri A, Studer L, Wernig M, Christian KM. Cellular reprogramming: recent advances in modeling neurological diseases. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2011 Nov 9; 31(45):16070-5. PMC3236609
Yang Z, Ming GL, Song H. Postnatal neurogenesis in the human forebrain: from two migratory streams to dribbles. Cell stem cell. 2011 Nov 4; 9(5):385-6. PMC3218098
McGurk JS, Shim S, Kim JY, Wen Z, Song H, Ming GL. Postsynaptic TRPC1 function contributes to BDNF-induced synaptic potentiation at the developing neuromuscular junction. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2011 Oct 12; 31(41):14754-62. PMC3213207
Guo JU, Ma DK, Mo H, Ball MP, Jang MH, Bonaguidi MA, Balazer JA, Eaves HL, Xie B, Ford E, Zhang K, Ming GL, Gao Y, Song H. Neuronal activity modifies the DNA methylation landscape in the adult brain. Nature neuroscience. 2011 Aug 28; 14(10):1345-51. PMC3183401
Guo JU, Su Y, Zhong C, Ming GL, Song H. Emerging roles of TET proteins and 5-hydroxymethylcytosines in active DNA demethylation and beyond. Cell cycle (Georgetown, Tex.). 2011 Aug 15; 10(16):2662-8. PMC3219536
Namba T, Ming GL, Song H, Waga C, Enomoto A, Kaibuchi K, Kohsaka S, Uchino S. NMDA receptor regulates migration of newly generated neurons in the adult hippocampus via Disrupted-In-Schizophrenia 1 (DISC1). Journal of neurochemistry. 2011 Jul; 118(1):34-44. PMC4142346
Bonaguidi MA, Wheeler MA, Shapiro JS, Stadel RP, Sun GJ, Ming GL, Song H. In vivo clonal analysis reveals self-renewing and multipotent adult neural stem cell characteristics. Cell. 2011 Jun 24; 145(7):1142-55. PMC3124562
Wang Y, Kaneko N, Asai N, Enomoto A, Isotani-Sakakibara M, Kato T, Asai M, Murakumo Y, Ota H, Hikita T, Namba T, Kuroda K, Kaibuchi K, Ming GL, Song H, Sawamoto K, Takahashi M. Girdin is an intrinsic regulator of neuroblast chain migration in the rostral migratory stream of the postnatal brain. The Journal of neuroscience: the official journal of the Society for Neuroscience. 2011 Jun 1; 31(22):8109-22.
Ming GL, Song H. Adult neurogenesis in the mammalian brain: significant answers and significant questions. Neuron. 2011 May 26; 70(4):687-702. PMC3106107
Juopperi TA, Song H, Ming GL. Modeling neurological diseases using patient-derived induced pluripotent stem cells. Future neurology. 2011 May; 6(3):363-373. PMC3125717
Guo JU, Su Y, Zhong C, Ming GL, Song H. Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain. Cell. 2011 Apr 29; 145(3):423-34. PMC3088758
Sun J, Sun J, Ming GL, Song H. Epigenetic regulation of neurogenesis in the adult mammalian brain. The European journal of neuroscience. 2011 Mar; 33(6):1087-93. PMC3076719
Zhang G, Lehmann HC, Manoharan S, Hashmi M, Shim S, Ming GL, Schnaar RL, Lopez PH, Bogdanova N, Sheikh KA. Anti-ganglioside antibody-mediated activation of RhoA induces inhibition of neurite outgrowth. The Journal of neuroscience: the official journal of the Society for Neuroscience. 2011 Feb 2; 31(5):1664-75. PMC3758521
Yang Z, Ming GL, Song H. Genetically targeting new neurons in the adult hippocampus. Cell research. 2011 Feb; 21(2):220-2. PMC3193443
Lee MH, Wang T, Jang MH, Steiner J, Haughey N, Ming GL, Song H, Nath A, Venkatesan A. Rescue of adult hippocampal neurogenesis in a mouse model of HIV neurologic disease. Neurobiology of disease. 2011; 41(3):678-87. PMC3049915
Chiang CH, Su Y, Wen Z, Yoritomo N, Ross CA, Margolis RL, Song H, Ming GL. Integration-free induced pluripotent stem cells derived from schizophrenia patients with a DISC1 mutation. Molecular psychiatry. 2011; 16(4):358-60. PMC4005725
2010
Ma DK, Marchetto MC, Guo JU, Ming GL, Gage FH, Song H. Epigenetic choreographers of neurogenesis in the adult mammalian brain. Nature neuroscience. 2010 Nov; 13(11):1338-44. PMC3324277
Shim S, Ming GL. Roles of channels and receptors in the growth cone during PNS axonal regeneration. Experimental neurology. 2010 May; 223(1):38-44. PMC2849920
Jablonska B, Aguirre A, Raymond M, Szabo G, Kitabatake Y, Sailor KA, Ming GL, Song H, Gallo V. Chordin-induced lineage plasticity of adult SVZ neuroblasts after demyelination. Nature neuroscience. 2010 May; 13(5):541-50. PMC4059417
Kim PM, Duan X, Huang AS, Liu CY, Ming GL, Song H, Snyder SH. Aspartate racemase, generating neuronal D-aspartate, regulates adult neurogenesis. Proceedings of the National Academy of Sciences of the United States of America. 2010 Feb 16; 107(7):3175-9. PMC2840285
Christian K, Song H, Ming GL. Adult neurogenesis as a cellular model to study schizophrenia. Cell cycle (Georgetown, Tex.). 2010 Feb 15; 9(4):636-7.
2009
Shim S, Yuan JP, Kim JY, Zeng W, Huang G, Milshteyn A, Kern D, Muallem S, Ming GL, Worley PF. Peptidyl-prolyl isomerase FKBP52 controls chemotropic guidance of neuronal growth cones via regulation of TRPC1 channel opening. Neuron. 2009 Nov 25; 64(4):471-83. PMC2786904
Ma DK, Ming GL, Song H. Oxysterols drive dopaminergic neurogenesis from stem cells. Cell stem cell. 2009 Oct 2; 5(4):343-4.
Kim JY, Duan X, Liu CY, Jang MH, Guo JU, Pow-anpongkul N, Kang E, Song H, Ming GL. DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212. Neuron. 2009 Sep 24; 63(6):761-73. PMC3075620
Ma DK, Kim WR, Ming GL, Song H. Activity-dependent extrinsic regulation of adult olfactory bulb and hippocampal neurogenesis. Annals of the New York Academy of Sciences. 2009 Jul; 1170:664-73. PMC2729764
Ma DK, Ponnusamy K, Song MR, Ming GL, Song H. Molecular genetic analysis of FGFR1 signalling reveals distinct roles of MAPK and PLCgamma1 activation for self-renewal of adult neural stem cells. Molecular brain. 2009 Jun 8; 2:16. PMC2700800
Ma DK, Bonaguidi MA, Ming GL, Song H. Adult neural stem cells in the mammalian central nervous system. Cell research. 2009 Jun; 19(6):672-82. PMC2738865
Ma DK, Guo JU, Ming GL, Song H. DNA excision repair proteins and Gadd45 as molecular players for active DNA demethylation. Cell cycle (Georgetown, Tex.). 2009 May 15; 8(10):1526-31. PMC2738863
Ming GL, Song H. DISC1 partners with GSK3beta in neurogenesis. Cell. 2009 Mar 20; 136(6):990-2.
Ma DK, Jang MH, Guo JU, Kitabatake Y, Chang ML, Pow-Anpongkul N, Flavell RA, Lu B, Ming GL, Song H. Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis. Science (New York, N.Y.). 2009 Feb 20; 323(5917):1074-7. PMC2726986
Nguyen T, Mehta NR, Conant K, Kim KJ, Jones M, Calabresi PA, Melli G, Hoke A, Schnaar RL, Ming GL, Song H, Keswani SC, Griffin JW. Axonal protective effects of the myelin-associated glycoprotein. The Journal of neuroscience: the official journal of the Society for Neuroscience. 2009 Jan 21; 29(3):630-7. PMC2774126
Cundiff P, Liu L, Wang Y, Zou J, Pan YW, Abel G, Duan X, Ming GL, Englund C, Hevner R, Xia Z. ERK5 MAP kinase regulates neurogenin1 during cortical neurogenesis. PloS one. 2009; 4(4):e5204. PMC2664926
2008
Eisch AJ, Cameron HA, Encinas JM, Meltzer LA, Ming GL, Overstreet-Wadiche LS. Adult neurogenesis, mental health, and mental illness: hope or hype? The Journal of neuroscience: the official journal of the Society for Neuroscience. 2008 Nov 12; 28(46):11785-91. PMC2793333
Goh EL, Young JK, Kuwako K, Tessier-Lavigne M, He Z, Griffin JW, Ming GL. beta1-integrin mediates myelin-associated glycoprotein signaling in neuronal growth cones. Molecular brain. 2008 Oct 15; 1:10. PMC2576245
Faulkner RL, Jang MH, Liu XB, Duan X, Sailor KA, Kim JY, Ge S, Jones EG, Ming GL, Song H, Cheng HJ. Development of hippocampal mossy fiber synaptic outputs by new neurons in the adult brain. Proceedings of the National Academy of Sciences of the United States of America. 2008 Sep 16; 105(37):14157-62. PMC2544594
Ge S, Sailor KA, Ming GL, Song H. Synaptic integration and plasticity of new neurons in the adult hippocampus. The Journal of physiology. 2008 Aug 15; 586(16):3759-65. PMC2538931
Ma DK, Chiang CH, Ponnusamy K, Ming GL, Song H. G9a and Jhdm2a regulate embryonic stem cell fusion-induced reprogramming of adult neural stem cells. Stem cells (Dayton, Ohio). 2008 Aug; 26(8):2131-41. PMC4059405
Li X, Ming GL. Using chips to simulate the brain as a tool to investigate brain development. Expert review of neurotherapeutics. 2008 Jul; 8(7):1001-4.
Joanne Wang C, Li X, Lin B, Shim S, Ming GL, Levchenko A. A microfluidics-based turning assay reveals complex growth cone responses to integrated gradients of substrate-bound ECM molecules and diffusible guidance cues. Lab on a chip. 2008 Feb; 8(2):227-37.
Duan X, Kang E, Liu CY, Ming GL, Song H. Development of neural stem cell in the adult brain. Current opinion in neurobiology. 2008 Feb; 18(1):108-15. PMC2464621
2007
Jordan JD, Ma DK, Ming GL, Song H. Cellular niches for endogenous neural stem cells in the adult brain. CNS & neurological disorders drug targets. 2007 Oct; 6(5):336-41.
Duan X, Chang JH, Ge S, Faulkner RL, Kim JY, Kitabatake Y, Liu XB, Yang CH, Jordan JD, Ma DK, Liu CY, Ganesan S, Cheng HJ, Ming GL, Lu B, Song H. Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brain. Cell. 2007 Sep 21; 130(6):1146-58. PMC2002573
Wen Z, Han L, Bamburg JR, Shim S, Ming GL, Zheng JQ. BMP gradients steer nerve growth cones by a balancing act of LIM kinase and Slingshot phosphatase on ADF/cofilin. The Journal of cell biology. 2007 Jul 2; 178(1):107-19. PMC2064427
Ge S, Yang CH, Hsu KS, Ming GL, Song H. A critical period for enhanced synaptic plasticity in newly generated neurons of the adult brain. Neuron. 2007 May 24; 54(4):559-66. PMC2040308
Ge S, Pradhan DA, Ming GL, Song H. GABA sets the tempo for activity-dependent adult neurogenesis. Trends in neurosciences. 2007 Jan; 30(1):1-8.
Kitabatake Y, Sailor KA, Ming GL, Song H. Adult neurogenesis and hippocampal memory function: new cells, more plasticity, new memories? Neurosurgery clinics of North America. 2007 Jan; 18(1):105-13, x.
Shim S, Ming GL. Signaling of secreted semaphorins in growth cone steering. Advances in experimental medicine and biology. 2007; 600:52-60.
2006
Kim YS, Martinez T, Deshpande DM, Drummond J, Provost-Javier K, Williams A, McGurk J, Maragakis N, Song H, Ming GL, Kerr DA. Correction of humoral derangements from mutant superoxide dismutase 1 spinal cord. Annals of neurology. 2006 Dec; 60(6):716-28.
Ming GL. Turning by asymmetric actin. Nature neuroscience. 2006 Oct; 9(10):1201-3.
Sailor KA, Ming GL, Song H. Neurogenesis as a potential therapeutic strategy for neurodegenerative diseases. Expert opinion on biological therapy. 2006 Sep; 6(9):879-90.
Kim J, Schafer J, Ming GL. New directions in neuroregeneration. Expert opinion on biological therapy. 2006 Aug; 6(8):735-8.
Ge S, Goh EL, Sailor KA, Kitabatake Y, Ming GL, Song H. GABA regulates synaptic integration of newly generated neurons in the adult brain. Nature. 2006 Feb 2; 439(7076):589-93. PMC1420640
Zhao C, Teng EM, Summers RG Jr, Ming GL, Gage FH. Distinct morphological stages of dentate granule neuron maturation in the adult mouse hippocampus. The Journal of neuroscience: the official journal of the Society for Neuroscience. 2006 Jan 4; 26(1):3-11.
Jordan JD, Ming GL, Song H. Adult neurogenesis as a potential therapy for neurodegenerative diseases. Discovery medicine. 2006; 6(34):144-7.
2005
Ma DK, Ming GL, Song H. Glial influences on neural stem cell development: cellular niches for adult neurogenesis. Current opinion in neurobiology. 2005 Oct; 15(5):514-20.
Shim S, Goh EL, Ge S, Sailor K, Yuan JP, Roderick HL, Bootman MD, Worley PF, Song H, Ming GL. XTRPC1-dependent chemotropic guidance of neuronal growth cones. Nature neuroscience. 2005 Jun; 8(6):730-5. PMC4005724
Ming GL, Song H. Adult neurogenesis in the mammalian central nervous system. Annual review of neuroscience. 2005; 28:223-50.
2004
Ren XR, Ming GL, Xie Y, Hong Y, Sun DM, Zhao ZQ, Feng Z, Wang Q, Shim S, Chen ZF, Song HJ, Mei L, Xiong WC. Focal adhesion kinase in netrin-1 signaling. Nature neuroscience. 2004 Nov; 7(11):1204-12.
Wen Z, Guirland C, Ming GL, Zheng JQ. A CaMKII/calcineurin switch controls the direction of Ca(2+)-dependent growth cone guidance. Neuron. 2004 Sep 16; 43(6):835-46.
Lie DC, Song H, Colamarino SA, Ming GL, Gage FH. Neurogenesis in the adult brain: new strategies for central nervous system diseases. Annual review of pharmacology and toxicology. 2004; 44:399-421.
2003
Goh EL, Ma D, Ming GL, Song H. Adult neural stem cells and repair of the adult central nervous system. Journal of hematotherapy & stem cell research. 2003 Dec; 12(6):671-9.
2002
Ming GL, Wong ST, Henley J, Yuan XB, Song HJ, Spitzer NC, Poo MM. Adaptation in the chemotactic guidance of nerve growth cones. Nature. 2002 May 23; 417(6887):411-8.
Kao HT, Song HJ, Porton B, Ming GL, Hoh J, Abraham M, Czernik AJ, Pieribone VA, Poo MM, Greengard P. A protein kinase A-dependent molecular switch in synapsins regulates neurite outgrowth. Nature neuroscience. 2002 May; 5(5):431-7.
1997
de la Torre JR, Höpker VH, Ming GL, Poo MM, Tessier-Lavigne M, Hemmati-Brivanlou A, Holt CE. Turning of retinal growth cones in a netrin-1 gradient mediated by the netrin receptor DCC. Neuron. 1997; 19(6):1211-24.
Ming GL, Song HJ, Berninger B, Holt CE, Tessier-Lavigne M, Poo MM. cAMP-dependent growth cone guidance by netrin-1. Neuron. 1997; 19(6):1225-35.
Ming Gl, Lohof AM, Zheng JQ. Acute morphogenic and chemotropic effects of neurotrophins on cultured embryonic Xenopus spinal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 1997; 17(20):7860-71.
Song HJ, Ming GL, Poo MM. cAMP-induced switching in turning direction of nerve growth cones. Nature. 1997; 388(6639):275-9.